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Tag: Mutations

Genetic mutation
A research paper published in Nature Medicine has shown the results of a broad investigation into gene variants associated with healthspan [1]. Genome-wide association studies A genome-wide association study is an effort to use enormous databases and computational analysis to examine the genetic causes of disease [2]. Previous studies have evaluated the effects of genes...
Genes computer
Publishing in GeroScience, a team of researchers that included Nir Barzilai and Matt Kaeberlein examined genes that may affect both mitochondria and lifespan [1]. From the mitochondria to the nucleus Over time, evolution has moved mitochondrial DNA from the individual mitochondria to the nucleus, where they are better protected. SENS Research Foundation, in conjunction with...
Breast cancer
Cells from the breasts of women with mutations that increase their risk of breast cancer show signs of accelerated aging, according to new research [1]. Accelerated aging may make these cells worse at suppressing cancer development, offering both an explanation for the effect of these mutations and an unexplored path for possible treatments. Risky mutations...
Small plate of food
Researchers have taken a look at how caloric restriction seems to improve intestinal stem cell function in a new open-access study. Inflammaging is a precursor of age-related diseases The lining of the intestines helps to prevent the entry of microbes and unwanted molecules into the bloodstream beyond; however, as we age, the integrity of this...

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