×

Tag: Mitochondria

Rabbit eating carrot
In Nature Communications, researchers have published their discovery of a compound found in carrots that promotes mitochondrial health and improves the physical abilities of older mice. Walking down the caloric restriction pathway Although it is difficult to establish in human beings, caloric restriction is one of the most well-known interventions known to be effective across...
Arthritis treatment
In the Journal of Nanobiotechnology, researchers have found that embedding microvesicles in a slow-release hydrogel may be an effective treatment for osteoarthritis. A line of inquiry begins to bear fruit Researchers have repeatedly found that the extracellular vesicles (EVs) released by stem cells, particularly mesenchymal stem cells (MSCs), are the main drivers behind the effectiveness...
Gift giving
In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient against energy deficiencies. A relatively recent discovery It was not until 2006 when a team of researchers realized that mitochondria were not restricted to their cellular environments, as...
Cells and DNA
Scientists have found that leakage of mitochondrial DNA in senescent cells is a major cause of their pro-inflammatory activity, and it can be targeted without clearing those cells out [1]. A new aspect of senescence Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or...
Calcium
Scientists have reported in Nature Aging that impaired mitochondrial uptake of calcium ions leads to changes in inflammatory responses that resemble what happens in aging [1]. Inflammation and aging Inflammation is an essential, evolutionarily conserved process and a fundamental part of the immune response, providing immediate defense against infections by pathogens such as bacteria, viruses,...
The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.
The Journal Club returns on 25th July at 12:00 Eastern time to the Lifespan.io Facebook channel. Editing mitochondrial DNA (mtDNA) has long been a challenge and systems such as CRISPR, which make editing regular DNA faster and easier, are very difficult to use when it comes to mtDNA. This month we are going to take...