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Tag: Mitochondria

AKG may be a useful supplement for slowing down aging.
Alpha-ketoglutarate (AKG) has long been a popular sports supplement and is often used in the bodybuilding world, but interest in this molecule has now reached the aging research field due to its central role in metabolism. What is alpha-ketoglutarate? AKG is a naturally occurring endogenous intermediary metabolite and part of the Krebs cycle, which means...
Blood cells
Researchers have reversed the age-related decline in the function of hematopoietic stem cells (HSCs) in older mice using nicotinamide riboside. This success can make our blood more youthful and increase the effectiveness of stem cell transplantation [1]. There will be blood HSCs are the progenitors of all our blood cells. HSCs reside in the bone...
High throughput screening
Researchers from the Laboratory for Cell Function Dynamics in Japan have developed a new method for detecting mitophagy, the process of recycling damaged mitochondria. The Necessity of Mitophagy Our mitochondria are the powerhouses of our cells, turning the food we eat into ATP, the form of chemical energy that our cells use. However, over time,...
X10 biological battery breakdown
Our mitochondria, which originated from ancient bacteria, act like batteries, giving our cells the energy they need to live. In this informative episode of X10, Veera explains what happens to these organelles with aging and what we can do about it...
Mouse with prominent whiskers
A group of researchers has demonstrated that treatment with NMN, a precursor of NAD+, restores neurovascular coupling (NVC) in aged mice [1]. Since NVC deficiency seems to be a major factor in the age-related decline of cognitive and motor functions, this discovery presents exciting new possibilities for longevity research. Neurovascular coupling While the human brain...
Heart Vector
As aging is a major risk factor for developing cardiovascular diseases, their prevalence rises rapidly with advancing age. A new study sheds light on our cells' declining ability to provide quality control for mitochondria, which spurs other aspects of aging. The loss of mitophagy accelerates aging The mitochondria are well-known as being the powerhouses of...