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Tag: Mitochondria

A picture of the Alpha-ketoglutarate molecule
September 07, 2020
Alpha-ketoglutarate (AKG) has long been a popular sports supplement and is often used in the bodybuilding world, but interest in this molecule has now reached the aging research field due to its central role in metabolism. History of alpha-ketoglutarate Alpha-ketoglutarate (AKG) was discovered in 1937 by Hans Adolf Krebs and William Arthur Johnson at the...
High throughput screening
May 28, 2020
Researchers from the Laboratory for Cell Function Dynamics in Japan have developed a new method for detecting mitophagy, the process of recycling damaged mitochondria. The Necessity of Mitophagy Our mitochondria are the powerhouses of our cells, turning the food we eat into ATP, the form of chemical energy that our cells use. However, over time,...
X10 biological battery breakdown
May 07, 2020
Our mitochondria, which originated from ancient bacteria, act like batteries, giving our cells the energy they need to live. In this informative episode of X10, Veera explains what happens to these organelles with aging and what we can do about it...
Mouse with prominent whiskers
April 28, 2020
A group of researchers has demonstrated that treatment with NMN, a precursor of NAD+, restores neurovascular coupling (NVC) in aged mice [1]. Since NVC deficiency seems to be a major factor in the age-related decline of cognitive and motor functions, this discovery presents exciting new possibilities for longevity research. Neurovascular coupling While the human brain...
Heart Vector
March 18, 2020
As aging is a major risk factor for developing cardiovascular diseases, their prevalence rises rapidly with advancing age. A new study sheds light on our cells' declining ability to provide quality control for mitochondria, which spurs other aspects of aging. The loss of mitophagy accelerates aging The mitochondria are well-known as being the powerhouses of...
Lab mouse
March 11, 2020
A new mouse study has found that injecting healthy mitochondria from young mice into older mice improves learning and memory, skeletal muscle function, and immune system activity [1]. The Aging Mitochondria Mitochondria are incredibly important components of our cells, as they produce energy in the form of ATP, the "molecular unit of currency" of intracellular...