August 15, 2023
Scientists have found that bubbles secreted by embryonic stem cells counter cellular senescence, in large part due to just two tiny snippets of RNA [1]. Helpful bubbles Extracellular vesicles (EVs) are membrane-bound tiny bubbles that are loaded with various molecular cargo, such as proteins, DNA, or RNA, that cells secrete as a method of intercellular...
July 10, 2023
A paper published in Aging goes into detail about the proteins and RNA pieces that increase and decrease with aging, suggesting a multiple-clock approach to biomarkers. Blood proteins change with age The researchers start out by discussing existing clocks based on such measurements as imaging [1] and epigenetic methylation [2], which is the most well-known...
April 15, 2021
A massive RNA sequencing effort has identified changes in microRNA associated with Parkinson's. Some of the changes correlated with disease progression, holding out hope that they could be useful as prognostic or diagnostic biomarkers to help guide research and evaluate potential therapies. Pinning down Parkinson's Although Parkinson's disease is the second most common neurodegenerative disease...
September 15, 2020
A group of researchers has found that extracellular vesicles carrying a specific type of microRNA can attenuate age-related inflammation and increase immune response following flu vaccination in mice [1]. Extracellular vesicles (EVs) are an important part of intercellular communication. These tiny nanoscale bubbles are secreted by cells into the intercellular space and can carry various...