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Tag: Loss of proteostasis

June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer's disease. Cellular senescence As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do not divide or support the tissues of which they...
April 23, 2020
Last week featured Cecilia Brunello discussing proteostasis; for this week's trivia episode of X10, she created a related quiz for Nicola and Giuliano to answer. Are they, in fact, pros at proteostasis? (adsbygoogle = window.adsbygoogle || []).push({});
April 09, 2020
In this talk episode, Nicola, Veera, and Cecilia Brunello of Helsinki University discuss loss of proteostasis, the primary hallmark of aging that leads to Alzheimer's and other deadly disorders. (adsbygoogle = window.adsbygoogle || []).push({});
February 13, 2020
On this informative episode of X10, Giuliano explains proteins and how they misfold, causing the hallmark of aging known as loss of proteostasis- which leads to Alzheimer's disease and other dangerous diseases.  (adsbygoogle = window.adsbygoogle || []).push({});
August 29, 2019
In a recent study, a team of researchers has discovered that a naturally occurring protein called Lipocalin-type prostaglandin D synthase (L-PGDS) prevents, and can destroy, the protein aggregates associated with Alzheimer's disease. Surprisingly common and with critical functions L-PGDS is a common protein, second only to albumin, in the human brain. It provides several critical...
July 26, 2019
Researchers from the Beijing Institute of Brain Disorders have discovered a new method of using exosomes to deliver aptamers that prevent the accumulation of α-synuclein aggregates, which are the cause of Parkinson's disease [1]. α-Synuclein Aggregates Like Alzheimer's, Parkinson's disease is characterized by protein aggregation caused by a loss of proteostasis, one of the hallmarks...