March 24, 2025
Like many people, I’m both wary of and intrigued by people who make bombastic claims. Years in the longevity field have taught me caution but also that big claims are not necessarily outlandish, and few people make bigger claims than Joshua “Scotch” McClure, founder and CEO of Maxwell Biosciences. The company developed Claromers™, synthetic small...
March 21, 2022
A research paper that has just been peer reviewed and published in Nature has described how disrupting an immune pathway that is upregulated in aging decreases the lethality of COVID-19 in a mouse model. Mice with COVID-19 As the researchers explain, normal mice do not use the same angiotensin converting enzyme 2 (ACE2) as humans,...
July 22, 2021
Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of the disease and may help explain why COVID-19 has a more severe effect on older people. A tangled skein The enormous impact of COVID-19 around...
January 20, 2021
New research published in Aging has analyzed the telomeres of patients hospitalized due to COVID-19. Why We Age: Telomere AttritionTelomeres are DNA regions located at the ends of a chromosome. Their normal length is 8-10 thousand base pairs, yet they consist of repetitions of a single sequence: TTAGGG. Telomeres do not code for proteins, but...
