April 28, 2023
Scientists have discovered that the protein Netrin-1 alleviates the age-related decline in hematopoietic stem cell function in mice, enhancing HSC transplantation and protecting these mice from the harmful effects of chemotherapy [1]. (Not) a niche problem Why we Age: Stem Cell ExhaustionStem cell exhaustion is the age-related deficiency of stem cells. This particular hallmark is...
September 29, 2021
A review published in The Malaysian Journal of Medical Sciences has outlined what effects caloric restriction (CR) has on the development and differentiation of stem cells. Stem cells and their exhaustion The reviewers began by discussing stem cell exhaustion, a hallmark of aging and a common concern of aging research that we have covered extensively....
May 18, 2021
Researchers have reversed the age-related decline in the function of hematopoietic stem cells (HSCs) in older mice using nicotinamide riboside. This success can make our blood more youthful and increase the effectiveness of stem cell transplantation [1]. There will be blood HSCs are the progenitors of all our blood cells. HSCs reside in the bone...