Tag: Healthspan

In a recent study, researchers investigated how restricting dietary methionine and inhibiting the tyrosine degradation pathway affects healthspan in aged mice. While affecting tyrosine didn’t show any benefits, methionine restriction improved many, but not all, measures of healthspan, including frailty, pathological disease burden, and neuromuscular function [1]. Aging of metabolism Changes in metabolism accompany aging...

A recent study investigated the impact of eight different mid-life dietary patterns on the odds of healthy aging, including cognitive, mental, and physical health [1]. You are what you eat Diet is an easily modifiable intervention in aging, as what we eat has a tremendous impact on our health. There is a wealth of evidence...

The authors of a recent study describe Ginkgolide B, a compound with senotherapeutic potential that improved muscle health, metabolism, frailty, inflammation, and senescence metrics and increased lifespan in female mice [1]. From East Asia to the clinic Ginkgolide B is a compound that can be extracted from Ginkgo biloba, an East Asian tree known as...

According to a new study, prolonged severe caloric restriction in hens, known as “molting”, restores their egg-laying capacity, slows aging, and increases survival [1]. Lay fast, die young The domestic hen is not the go-to animal model in aging studies, but perhaps it could offer new insights. A hen’s lifespan is about 6-8 years, which...

Eric Le Bourg has published a thought-provoking paper in Biogerontology that offers a critique of geroscience [1]. Geroscience, we need to talk... When people discuss the prospects of targeting the aging processes to prevent, halt, or even reverse age-related diseases, their beliefs often fall into two opposing categories. The first is overly optimistic blue-sky thinking,...

Every day, researchers get together in their labs and try to find ways of bringing aging under medical control. Despite the ongoing global effort, it is estimated that a relatively complete system of controlling biological aging is at least 20 years away. That means there is likely going to be considerable time before life extension...