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Tag: Gut

Intestinal molecules
Scientists have shown that the NAD+ precursor nicotinamide riboside (NR) alleviates symptoms of leaky gut caused by ethanol consumption in mice by improving mitochondrial function [1]. What is Nicotinamide Riboside? Benefits and Side EffectsNicotinamide riboside (NR) is a B3 vitamin. Nicotinamide riboside gets converted into nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for life.Read MoreCategory:...
Mice eating
According to a new study, the age-related increase in intestinal permeability that drives inflammation can be alleviated by inhibiting the enzyme arginase, a regulator of nitric oxide production [1]. Gut feeling While age-related sterile inflammation (inflammaging) is considered one of the hallmarks of aging and a major cause of age-related diseases [2], scientists still don't...
Journal Club
Journal Club returns live on our Facebook channel on October 25th at 12:00 Eastern time. Dr. Oliver Medvedik will be taking a look at a recent study published in Nature Aging that has shown that short-term rapamycin treatment in early adulthood extends lifespan in flies and improves gut health in both flies and mice [1]....
Young and old mice
A study published in Nature Aging has shown that short-term rapamycin treatment in early adulthood extends lifespan in flies and improves gut health in both flies and mice [1]. A well-studied drug Rapamycin, an inhibitor of mTOR signaling, is capable of extending the lifespan of several organisms and is thus believed to be one of...
Mouse eating
Publishing in Microbiome, a team of researchers has ascertained multiple physical effects of aging gut flora in mice. Antibiotics and fecal transfers The researchers used three groups of mice: young (3 months), old (18 months), and aged (24 months). Young and old groups were divided into a control group, an antibiotics group, and three recipient...
Parkinson's
A study published in Cell Reports has found Ξ±-synuclein, the fundamental protein of Parkinson's disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson's disease, which causes damage to the portion of the brain responsible for movement, is widely known to be caused by the aggregation of Ξ±-synuclein. This...