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Tag: Gut

Journal Club
Journal Club returns live on our Facebook channel on October 25th at 12:00 Eastern time. Dr. Oliver Medvedik will be taking a look at a recent study published in Nature Aging that has shown that short-term rapamycin treatment in early adulthood extends lifespan in flies and improves gut health in both flies and mice [1]....
Young and old mice
A study published in Nature Aging has shown that short-term rapamycin treatment in early adulthood extends lifespan in flies and improves gut health in both flies and mice [1]. A well-studied drug Rapamycin, an inhibitor of mTOR signaling, is capable of extending the lifespan of several organisms and is thus believed to be one of...
Mouse eating
Publishing in Microbiome, a team of researchers has ascertained multiple physical effects of aging gut flora in mice. Antibiotics and fecal transfers The researchers used three groups of mice: young (3 months), old (18 months), and aged (24 months). Young and old groups were divided into a control group, an antibiotics group, and three recipient...
Parkinson's
A study published in Cell Reports has found α-synuclein, the fundamental protein of Parkinson's disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson's disease, which causes damage to the portion of the brain responsible for movement, is widely known to be caused by the aggregation of α-synuclein. This...
Plant-Based Diet
The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60 years and older [1].  Age has been reported to be a risk factor for increased intestinal permeability over the age of 50 [2]. The authors...
Three Baby Mice
A study published in Cell Reports has shown that early-life exposure to antibiotics that destroy the gut flora can harm the lifelong development of mice, including lifespan. Three groups with different microbiota To begin the study, the researchers fed 20 baby mice, as well as their mothers, amoxicillin and neomycin, and they established a control...

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