January 11, 2023
Scientists have shown that the NAD+ precursor nicotinamide riboside (NR) alleviates symptoms of leaky gut caused by ethanol consumption in mice by improving mitochondrial function [1]. What is Nicotinamide Riboside? Benefits and Side EffectsNicotinamide riboside (NR) is a B3 vitamin. Nicotinamide riboside gets converted into nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for life.Read MoreCategory:...
November 15, 2022
According to a new study, the age-related increase in intestinal permeability that drives inflammation can be alleviated by inhibiting the enzyme arginase, a regulator of nitric oxide production [1]. Gut feeling While age-related sterile inflammation (inflammaging) is considered one of the hallmarks of aging and a major cause of age-related diseases [2], scientists still don't...
October 04, 2022
Journal Club returns live on our Facebook channel on October 25th at 12:00 Eastern time. Dr. Oliver Medvedik will be taking a look at a recent study published in Nature Aging that has shown that short-term rapamycin treatment in early adulthood extends lifespan in flies and improves gut health in both flies and mice [1]....
September 07, 2022
A study published in Nature Aging has shown that short-term rapamycin treatment in early adulthood extends lifespan in flies and improves gut health in both flies and mice [1]. A well-studied drug Rapamycin, an inhibitor of mTOR signaling, is capable of extending the lifespan of several organisms and is thus believed to be one of...
May 09, 2022
Publishing in Microbiome, a team of researchers has ascertained multiple physical effects of aging gut flora in mice. Antibiotics and fecal transfers The researchers used three groups of mice: young (3 months), old (18 months), and aged (24 months). Young and old groups were divided into a control group, an antibiotics group, and three recipient...
January 13, 2022
A study published in Cell Reports has found α-synuclein, the fundamental protein of Parkinson's disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson's disease, which causes damage to the portion of the brain responsible for movement, is widely known to be caused by the aggregation of α-synuclein. This...