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Tag: Extracellular Matrix

According to a new study published in Nature Scientific Reports, while both aerobic and resistance exercise improve some aspects of skin aging, only the latter is able to increase skin thickness [1]. Exercise and skin – an overlooked connection Skin is the largest organ of the human body, providing a barrier that keeps us safe...
Capillaries
A new publication in Nature Aging has explained a great deal about aging of the neurovascular system, showing where and how the brain's blood supply changes with aging in a mouse model. A branching network of blood vessels In the neurovascular system, arteries lead to arterioles, which then branch off into precapillary sphincters. These lead...
Skin fibroblast
Researchers publishing in Aging have identified an individual protein, secreted frizzled-related protein 4 (SFRP4), that is produced by senescent cells and contributes to skin aging in mice. The spread of the SASP Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues...
Collin_Ewald
Dr. Collin Ewald is a molecular biologist and a professor at the Swiss Federal Institute of Technology in ZΓΌrich (ETH). At ETH, Collin leads the Laboratory of Extracellular Matrix (ECM) Regeneration. Here, his research focuses on age-related ECM remodeling and related longevity interventions. We caught up with him to discuss his lab's development of the...
Hand arthritis
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer, more than a nuisance There are plenty of deadly age-related diseases, and then there are others that shorten our healthspan rather than lifespan, making the...
Hair Loss and Regrowth
Scientists showed that hair loss happens partially as a result of stem cells escaping from hair follicles. They also shot a stunning time-lapse video of the process. The stem cell cycle Stem cells reside in β€œstem cell compartments” in various tissues. By differentiating into multiple types of cells upon demand, they contribute to tissue regeneration....