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Tag: Extracellular Matrix

Hair Loss and Regrowth
Scientists showed that hair loss happens partially as a result of stem cells escaping from hair follicles. They also shot a stunning time-lapse video of the process. The stem cell cycle Stem cells reside in “stem cell compartments” in various tissues. By differentiating into multiple types of cells upon demand, they contribute to tissue regeneration....
Old and young collagen
A recent study published in Aging Cell has turned up potential new therapeutics to target the aging extracellular matrix (ECM). Longevity drug discovery  The discovery of new targets injects fresh lifeblood into the race to develop anti-aging compounds. The strategies used to identify these targets have seen significant innovation recently, with various types of databases...
Lab mouse
Molecular Psychiatry has recently published a report from the University of Cambridge detailing how the brain’s extracellular matrix (ECM) changes with age, negatively impacting memory, and how modifying the components of the brain ECM can revitalize memory in mice [1]. What is neuroplasticity? Neuroplasticity is the ability of neurons to form new connections. This ability...
Lung branches
A new review published in the American Journal of Respiratory Cell and Molecular Biology discusses the causes of, and potential treatments for, idiopathic pulmonary fibrosis (IPF). Fibrosis, but not focused on fibroblasts In the lungs, the trachea (airway) breaks out into a tree-like system of nodes. Each branch ends in alveoli, which are responsible for...
Spinal degradation
Recent research out of Frontiers in Pharmacology has shown that a natural herbal compound reduces senescence and intervertebral disc degeneration in mice. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they emit potentially harmful...
Heart scaffold
A new article published by the International Journal of Molecular Sciences sheds light on the differences between the extracellular matrix (ECM) of healthy people and people in end-stage heart failure. HeartThe heart is a four-chambered organ located between our lungs. Blood is pumped by the heart through two loops, one to the lungs, oxygenating the...