Tag: Exosomes

A new paper elaborates on how and why microglia fail to clean up the α-synuclein protein of Parkinson's disease, gradually making the disease worse. The aggregation of Parkinson's Why we Age: Loss of ProteostasisThe loss of proteostasis is the failure of the protein building machinery of the cell and the accumulation of misfolded proteins, which...

A new study used a plasma fraction from young pigs to robustly reduce the biological age of old rats. This could potentially open doors to rejuvenation in humans [1]. The blood connection People have been trying to use young blood to rejuvenate old organisms for millennia, but only in recent years has this concept been...

Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and maintaining human cartilage. An established approach This is far from the first attempt at treating osteoarthritis using stem cells. We have previously reported on a...

Researchers publishing in Aging have outlined how biochemical signals derived from created stem cells encourage blood vessels to form new branches in naturally aged mice. iPSCs, exosomes, and angiogenesis Exposure to the Yamanaka factors can cause ordinary cells to teturn to early stemness, from which they can divide into any other cell in the body....

Stem cell therapies have been developing and evolving rapidly over the last decade, and extracellular vesicles (EVs) are another innovative approach that researchers are exploring. EVs are being explored for their potential as the basis of new cell therapies, taking the signals generated from various types of stem cells and delivering just those signals, rather...