Tag: Dementia

Scientists have found a way to directly stimulate the assembly of Complex I in mitochondria, rescuing memory deficits in mouse models of Alzheimer’s and frontotemporal dementia [1]. Mitochondrial signal transducers Why We Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that...

Researchers have ascertained that excessive amounts of complement C3, an essential immune protein that increases with aging, are responsible for causing dementia in a mouse model. A necessary complement The complement system is a key immune system component that is involved in removing misfolded proteins, infectious diseases, and various cellular fragments from the brain [1]....

While the overall prevalence of dementia might be rising due to population aging, a study has found that today’s older people seem to be less prone to dementia than in the past [1]. Are we having more dementia or less? While the robust rise in average life expectancy seen in the previous century has largely...

The authors of a recent review analyzed the results of 14 studies that included 139 million people to identify patterns that connect dementia risk to commonly used medications [1]. Finding a new purpose Despite its prevalence in the elderly population, there is a lack of effective clinical treatments for dementia, and there is ongoing research...

A new study suggests that an anti-inflammatory diet can significantly reduce the risk of dementia and delay its onset even in people with existing cardiometabolic diseases [1]. Is it too late to lower the risk? Cardiometabolic diseases, such as type 2 diabetes, heart attack, and stroke, strongly contribute to the risk of developing dementia later...

A recent paper in the European Journal of Epidemiology reported that recurrent miscarriage and stillbirths are associated with the occurrence of dementia, but there was insufficient evidence to establish such a connection between infertility and dementia [1]. Sex-specific differences in dementia risk Dementia affects women more frequently than men. The authors of this paper discuss...