September 11, 2020
Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that can accurately measure biological age. Having such biomarkers is critical in the development of therapies that target the aging processes directly, and one of the...
August 11, 2020
Researchers have found that CLOCK, a protein that regulates the circadian cycle of our cells, also fights cellular senescence by promoting chromatin stability [1]. Since its very beginning, life on Earth had to adapt to our planet's natural 24-hour rotation cycle. Rising to the challenge, nature invented biological mechanisms called circadian clocks (from the Latin...
July 24, 2020
A team of researchers have developed a tissue-specific clock that can measure the biological age of skin. There is plenty of new evidence that different organs and tissues in our body age at different rates. In particular, the epigenetic state, the pattern of gene expression, of the cells that comprise these different organs and tissues...
July 22, 2020
Reason, author of the anti-aging blog Fight Aging and CEO of Repair Biotechnologies, still isn't convinced that methylation is very useful in assessing biological age or the efficacy of various therapeutics, despite the wide use of methylation-based clocks. He surprised me at this year's Longevity Therapeutics conference in San Francisco by speaking out about the...
June 19, 2020
Can we use the bacteria in our gut to measure how biologically old we are? Some researchers certainly think we can and have developed a microbiome clock that examines the bacteria living in our guts to predict our age. The microbiome The gut microbiome is a complex and ever-changing ecosystem populated by a myriad of...
June 02, 2020
Researchers have proposed a new epigenetic clock designed to measure subtle epigenetic changes in vitro [1]. They hope that their discovery will help to expedite the creation of new anti-aging drugs. Measuring biological age Aging research is all about the difference between chronological and biological age. The former is simply the passage of time, but...
