Tag: Clock

Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose of aging clocks One of the central questions of longevity research is how to measure biological age. If a pathology, genetic difference, lifestyle choice, or...

Recent data published in Neuropsychopharmacology has looked at changes in brain connectivity across lifespan and in patients with major depressive disorder. Biological and chronological age Your chronological age is simply the amount of time that has passed since you were born, but your biological age represents how your body has physically aged over that time....

These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using deep learning, has recently been created by the Hong Kong-based company Deep Longevity. There are two common ways to measure age: biological and chronological. The...

Dr. Steve Horvath is very well known in the field for his groundbreaking work on epigenetic clocks, which use one of the hallmarks of aging, epigenetic alterations, in order to calculate biological age. In his talk at Ending Age-Related Diseases 2020, he discussed how such clocks can be used to evaluate the effectiveness of rejuvenation...

A new study published in the Journals of Gerontology has shown that the epigenetic clock GrimAge is a strong predictor of the effects of aging, particularly all-cause mortality: the likelihood of dying from any cause. Did previous clocks use the wrong target? As the researchers explain, the first-generation epigenetic clocks of Drs. Horvath (who contributed...

Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that can accurately measure biological age. Having such biomarkers is critical in the development of therapies that target the aging processes directly, and one of the...