Tag: Clock

Researchers have shown that castration makes male sheep live longer, and they’ve also used genomic data to get a basic understanding of the mechanism behind this longevity [1]. While castration is unlikely to be part of a life extension therapy, unraveling its effect on lifespan will help flesh out the link between sex hormones and...

Researchers have developed a new transcriptomic aging clock that incorporates information about biological pathways. With this approach, the clock predicts not only age but also how the state of various genetic pathways changes with age, providing insight into the transcriptional changes involved in aging. Time for a new kind of clock In recent years, the...

A study funded by the National Institutes of Health has found that excessive alcohol consumption increases the epigenetic age of non-Hispanic White women according to the GrimAge epigenetic clock. Why we Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and increase the risk of cancer and...

People with major depressive disorder may have a biological age as much as two years greater than their chronological age, according to a new study [1]. The discovery provides a first step towards understanding the biological mechanisms that link depression to decreased lifespan. A link between depression and aging Depression is a serious global problem....

In a randomized, controlled human clinical trial, researchers have found that an eight-week program of diet, exercise, and meditation reduces epigenetic age by approximately two years in males between the ages of 50 and 72. A prescription for health For this study, the researchers used entirely conventional and widely recognized methods of improving health among...

Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose of aging clocks One of the central questions of longevity research is how to measure biological age. If a pathology, genetic difference, lifestyle choice, or...