Tag: Clock

Researchers publishing in Aging have found a correlation between cognitive decline and measurements of epigenetic aging. Familiar epigenetic clocks Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different kinds of clocks, and...

Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about the recent developments in this immensely important field, including pan-mammalian clocks, two-species clocks, and single-cell clocks, along with the challenges the field faces. You are...

In an important step for the longevity field, scientists have found that epigenetic age acceleration, as measured by four popular methylation clocks, is correlated with aging and mortality in humans [1]. Lack of human data Studying aging obviously requires having reliable biomarkers of aging. Epigenetic clocks that utilize the correlation between aging and genome methylation...

A new study published in Nature has reported on how caloric restriction, circadian rhythms, and molecular clocks interact to affect the ocular health and lifespan of fruit flies. Circadian rhythms, clock genes, and photoreceptors The researchers begin their paper by discussing the concept of circadian rhythms, which are the 24-hour cycles that organisms have evolved...

Using a Berlin cohort, a study published in GeroScience has uncovered a link between Vitamin D supplementation and a reduction of epigenetic age. On the back of previous work This study's cohort consisted of 60- to 85-year-old participants in the Berlin Aging Study II (BASE-II). The researchers had previously used data from this cohort to...

Scientists have shown that only some of the hallmarks of aging affect methylation clocks that are used to measure biological age [1]. The big black box Epigenetic clocks that measure biological age based on aging-related changes in genome methylation have been a great success. They enable researchers to analyze the effects of various interventions on...