Help us: Donate
Follow us on:
×

Menu

Back

Tag: Caloric Restriction

January 21, 2021
n this video, the Sheekey Science Show discusses the different types of fasting (periodic and intermittent) and how they relate to aging, including their beneficial effects on metabolism and stem cells, along with the concept of refeeding. Supplements that serve as caloric restriction mimetics, which replicate some of the effects of fasting, are also explored.
December 03, 2020
A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted therapeutic interventions. Less is more Dietary restriction is one of the most reliable ways to increase longevity, increasing lifespan in species from fruit flies to...
September 10, 2020
A short-term caloric restriction diet enhanced a DNA repair process known as non-homologous end joining. These results may partially explain how caloric restriction and similar diets increase lifespan and healthspan in a wide range of organisms. Eat less, live longer Caloric restriction – that is, reduced caloric intake without malnutrition – is one of the...
September 07, 2020
Alpha-ketoglutarate (AKG) has long been a popular sports supplement and is often used in the bodybuilding world, but interest in this molecule has now reached the aging research field due to its central role in metabolism. History of alpha-ketoglutarate Alpha-ketoglutarate (AKG) was discovered in 1937 by Hans Adolf Krebs and William Arthur Johnson at the...
August 05, 2020
Researchers have taken a look at how caloric restriction seems to improve intestinal stem cell function in a new open-access study. Inflammaging is a precursor of age-related diseases The lining of the intestines helps to prevent the entry of microbes and unwanted molecules into the bloodstream beyond; however, as we age, the integrity of this...
December 13, 2019
Building upon previous studies, a new study has unearthed critical facts about the basic biology behind the TORC1 pathway, identifying how caloric restriction leads to a chain of effects that activate the protein Maf1, repress RNA transcription, and slow genomic instability, which is one of the primary hallmarks of aging. A long chain of causes...