Tag: Caloric Restriction

A recent study from Penn State University may shed more light on the link between telomeres, aging, and why caloric restriction appears to influence them. Telomeres are linked to aging Telomeres are small protective caps on the ends of our chromosomes that guard our DNA. Telomere attrition, in which these caps slowly erode, is a...

In a recent Nature Communications paper, the researchers investigated changes in weight, metabolism, and microbiome that resulted from periodic restricted feeding in non-human primates [1]. Continuous vs. time-restricted caloric restriction Caloric restriction, which limits the amount of calories an organism consumes, is a widely known lifespan-extending intervention in laboratory animals [2]. How caloric restriction is...

According to a new study, prolonged severe caloric restriction in hens, known as “molting”, restores their egg-laying capacity, slows aging, and increases survival [1]. Lay fast, die young The domestic hen is not the go-to animal model in aging studies, but perhaps it could offer new insights. A hen’s lifespan is about 6-8 years, which...

New research in Aging Cell has identified senescence-associated biomarkers whose levels are altered by caloric restriction in humans [1]. Slowing down senescence with fewer calories Multiple animal studies have found that reducing caloric intake without causing malnutrition (caloric restriction) has great lifespan-extending potential and can delay the onset of several age-related diseases [2]. These studies...

A review published in the Journal of Internal Medicine summarized current knowledge on the impact of dietary factors on chronic diseases and longevity [1]. Restrict calories, live healthier and longer The choice of what someone eats obviously has a profound impact on that person's health, but the amount is also important. Caloric restriction, the practice...

In one of the first studies of its kind, the popular senolytic combination, administered systematically for six months, produced several health benefits in these animals. Some effects were augmented by caloric restriction [1]. Coup de grâce for cells The combination of the drug dasatinib and the flavonoid quercetin, also known as D+Q, is one of...