Tag: Autophagy

A study published in Human Nutrition & Metabolism found that prolonged intermittent fasting causes the expression of genes involved in autophagy, the inflammasome, and senescence to change [1]. Fasting your way to better health and longevity? Previous research has linked fasting to delaying the onset of age-related diseases and longevity along with positive outcomes in...

A study published in Aging Cell has reported that older people with better regulated autophagy in their skeletal muscles have less age-related frailty. Taking out the trash What is Autophagy?Autophagy, derived from ancient Greek, means "eating of self". Autophagy is the way cells break down misbehaving or nonfunctional organelles and proteins in the cell. This...

Experimenting in vitro and in mice, scientists have found that ovarian aging is linked to increased autophagy and apoptosis in granulosa cells and that it can be reversed by an estrogen receptor inhibitor [1]. When ovaries get tired Female reproductive aging is an intriguing phenomenon that remains understudied, although things have been changing recently. In...

A new study suggests that the flavonoid epicatechin, found in chocolate, tea, and berries, provides robust protection against reperfusion injury in myocardial infarction [1]. Reperfusion injury: friendly fire Myocardial infarction (heart attack) is the injury caused by complete or partial cessation of blood flow to a portion of the myocardium, the heart’s muscle tissue. This,...

In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. What is Autophagy?Autophagy, derived from ancient Greek, means "eating of self". Autophagy is the way cells break down misbehaving or nonfunctional organelles and proteins in the cell. This means that...

In a preprint paper, the researchers have shown that low-frequency ultrasound treatment decreases senescence and improves the physical performance of aged mice [1]. Mechanical approach Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they...