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NAD+ Mouse Launches on Today


Today, we are delighted to announce that we have launched a new crowdfunding campaign on the NAD+ Mouse Project by Dr. David Sinclair and his team at Harvard Medical School.

NAD+ is a vitally important molecule that is found in every cell in your body and is involved in DNA repair, tissue growth, nutrient sensing and metabolism, cell-to-cell signaling, and many other cellular processes. Quite simply, without NAD+, cells would not work and life would be impossible. If you would like to learn more about NAD+ and its role in aging, check out our articles here, here, and here.

Can NMN Increase Longevity?

Может ли NMN продлить жизнь?

The new project proposes to conduct a lifespan study on normally aged mice to see if the NAD+ precursor nicotinamide mononucleotide (NMN) can increase lifespan. During the study, the mice will be observed to see if the molecule can delay age-related decline and if it improves the health and lifespan of the animals. This will provide researchers with important data to help support human studies with NMN, and this world-first study could provide valuable information.

The team will also be testing the effects of NMN by using a special kind of mouse called ICE (Induced Changes In Epigenome). ICE mice experience accelerated aging, so initial results will arrive more quickly and can be validated against the longer-term lifespan study in the regular-aging mice. With these mice, the team will be observing changes to behavior, physical activity, and other markers.

Finally, thanks to the generosity of two anonymous donors, the first $10,000 donated to the campaign will be matched twice, effectively tripling the value of your donations! The campaign is live right now, and remember, donations of any size can and do make a difference.

About the author

Steve Hill

Steve serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 600 articles on the topic, interviewed over 100 of the leading researchers in the field, hosted livestream events focused on aging, as well as attending various medical industry conferences. His work has been featured in H+ magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, Swiss Monthly, Keep me Prime, and New Economy Magazine. Steve is one of three recipients of the 2020 H+ Innovator Award and shares this honour with Mirko Ranieri – Google AR and Dinorah Delfin – Immortalists Magazine. The H+ Innovator Award looks into our community and acknowledges ideas and projects that encourage social change, achieve scientific accomplishments, technological advances, philosophical and intellectual visions, author unique narratives, build fascinating artistic ventures, and develop products that bridge gaps and help us to achieve transhumanist goals. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project.
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