Month: August 2024

In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different kinds...

In Aging, researchers have described how the changing production of skin cells' proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy skin, dermal fibroblasts produce the proteins needed to maintain the extracellular matrix (ECM), the network of collagen and elastin that holds soft tissues together [1]....

A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related muscle loss Muscle loss is a common problem in the aging population. Studies estimate that “after age 50, adults lose approximately 1% of their muscle...

According to a new study, “weekend warriors”, people who have most of their physical activity over one or two days a week, enjoy the most robust risk reduction for several brain health-related conditions [1]. Couch potato, except on weekends Exercise is universally necessary to stay healthy for longer. It is one of the three staples...

LongX, an initiative dedicated to providing global early-career avenues into longevity, has concluded Cohort 1 of its first fully remote educational venture, the Xplore Program. The longevity community is welcome to attend the Xplore Program showcase event on Sep 7, 2024 to support the next generation of longevity talent. The virtual event will feature pitch...

Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down Nicotinamide Adenine Dinucleotide (NAD): Benefits and ResearchNicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. It is a dinucleotide, which means that it consists of two...