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Month: March 2023

LSN Young Blood
This episode of Lifespan News, presented by Emmett Short, discusses a study showing that the brains of old mice benefit by receiving the blood of young mice. Script Heterochronic parabiosis is a well-known aging intervention in mouse studies, and it works. You stitch two mice together so they share blood and, like Highlander, the old...
A new study using wearable accelerometers suggests that you don’t have to clock extreme numbers of steps every day to stay healthy [1]. Do you always need to hit the target? A tight association between physical activity and health is widely known [2]. In fact, staying fit might be the best anti-aging intervention currently available....
Elderly eye
An accepted manuscript in eLife Sciences has described eyeAge, a new clock that uses deep learning to analyze the eye in detail in order to predict chronological age and age acceleration. Retinal signs of aging This project was developed with the knowledge that fundus imagery, which shows the blood vessels at the back of the eye,...
Abstract DNA
In a new study published in Nature Structural and Molecular Biology, researchers have demonstrated that by manipulating the DREAM protein complex, a major regulator of DNA damage response, it might be possible to alter the number of DNA mutations accumulated with age [1]. Mutations and DREAMs DNA mutations spontaneously occur in both germ-line (reproductive) cells...
Baton passing
Scientists have shown that extracellular vesicles derived from senescent stem cells can improve the proliferation, viability, and migration capacity of healthy stem cells [1]. Cell-to-cell packages Extracellular vesicles (EVs, not to be confused with electric vehicles) are tiny membrane-bound bubbles that are emitted by cells and carry various molecular cargo such as proteins and miRNA....
Elderly smiling
A team of researchers has recently published a study on the effects of senescence on periodontal tissues in Aging. Connecting bones and teeth We have previously outlined a study showing a relationship between gum disease and biomarkers of inflammation. Noting that aging itself is a risk factor for periodontitis [1], this study approaches this topic...