March 31, 2022
Publishing in Aging, researchers from the Chengdu Jinjiang Hospital in China have discovered that caloric restriction is less effective on mice previously fed a high-calorie diet. Well-known effects In their introduction, the researchers discuss what caloric restriction is known to do, citing papers that show its effects on autophagy [1], inflammation [2], nutrient sensing [3],...
March 30, 2022
It seems bizarre that in 2022, some biotech companies interested in doing something about aging are still saying that they are not. Cellular rejuvenation seems to be the latest buzzword and an attempt to rebrand and escape the stigma of anti-aging. Genentech is another cellular rejuvenation company Recently, researchers at the Salk Institute, in collaboration...
March 30, 2022
Insilico Medicine, which uses AI for drug discovery, has identified potential dual-purpose therapeutic targets that are implicated in aging and age-associated diseases using artificial intelligence and a Hallmarks of Aging framework. The full press release is included here. March 29, 2022, New York (11AM ET) --- Insilico Medicine, a clinical stage end-to-end artificial intelligence (AI)-driven...
March 29, 2022
Scientists have shown that oleanoic acid, a nutrient most associated with olive oil, greatly improves numerous markers of cardiac health in aging mice [1]. is a nutrient abundant in some foods, particularly olive oil. Olive oil has been shown to have health benefits compared to most other types of oil, but this data comes mostly...
March 28, 2022
Research funded by the National Institutes of Health and published in Cell has thoroughly described a little-known amyloid aggregate that accumulates in the brains of people suffering from multiple proteostasis-related neurological disorders. Three classes of pathology, one protein fragment The authors of this study list three different classes of neurodegenerative protein disorders: TDP-43 proteinopathies, such...
March 25, 2022
In a population study, scientists have found that consuming foods associated with a low Diet Inflammatory Index substantially lowers the risk of dementia [1]. Aging is accompanied by an increase in chronic, low-grade inflammation, known as inflammaging, which has been linked to multiple age-related diseases. Inflammaging promotes cancer, diabetes, cardiovascular diseases, and various types of...