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Tag: AGEs

January 09, 2020
There are lots of exciting companies working in the aging field, and it's a great time to tell you about three of the more interesting ones. Most of these companies are a while away from human trials yet, but their innovations could possibly be truly game changing. Underdog Pharma Underdog Pharmaceuticals is a spin-off company...
January 08, 2020
Some pleasant news has recently arrived: Revel Pharmaceuticals has successfully completed a seed round in order to begin developing therapeutics that target glucosepane crosslinks, which are a proposed reason why we age, develop diseases such as diabetes, and suffer from stiffened arteries and hypertension. In the business of startups, a seed round refers to a...
June 03, 2019
For the May Journal Club, Dr. Medvedik and guests took a look at the recent publication by the Spiegel Lab at Yale University where two forms of advanced glycation end products (AGEs) were successfully cleaved. We also covered this important breakthrough in our article – Reversal of Two Advanced Glycation End Products Achieved. Abstract Advanced glycation end products...
May 17, 2019
Hosted by Dr. Oliver Medvedik, the May edition of Journal Club will focus on the recent publication by the Spiegel Lab at Yale University where two forms of advanced glycation end products were successfully cleaved. We already discussed this important breakthrough in our article - Reversal of Two Advanced Glycation End Products Achieved. Now we...
May 02, 2019
Today, we want to highlight a new study that shows, for the first time, that established AGEs can be reversed via therapeutic intervention. What are AGEs? Advanced glycation end products (AGEs) are harmful compounds that are created when proteins or fats combine with sugars in the bloodstream in a process known as glycation. AGEs can...
April 23, 2018
The Undoing Aging conference, a collaboration between the SENS Research Foundation and Michael Greve’s Forever Healthy Foundation, took place on March 15-17 in Berlin, and it saw many researchers, advocates, investors, and other important members of the longevity community gather together to learn about the latest progress in rejuvenation biotechnology. LEAF arranged a travel grant...