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September 11, 2026
Six different aging clocks detected younger blood protein profiles in patients taking the experimental lung-fibrosis drug rentosertib. This suggests possible anti-aging effects, but separating those from the narrower benefits of treating fibrosis remains a challenge [1]. The AI-developed drug Many drugs developed for particular diseases act on aging-related biological processes. That creates an opportunity: a...
September 08, 2026
In a new study, semaglutide given late in life increased median lifespan in female mice by more than 12% and improved various health markers. Semaglutide’s effect possibly went beyond caloric restriction [1]. Old mice, new drugs GLP-1 receptor agonists, which act on a hormone that regulates insulin secretion and appetite, have revolutionized obesity treatment, showing...
August 28, 2026
Michael Snyder, Director of the Center for Genomics and Personalized Medicine at Stanford University, is obsessed with health-tracking wearables. During our interview, he wore four wrist-worn devices – watches and bands – and two rings. He is convinced that these small but powerful gadgets will help drive the transition from today’s “sickcare” to true healthcare,...
August 21, 2026
A new study suggests that in amyotrophic lateral sclerosis – and possibly other neurodegenerative diseases – the brain’s immune cells devour stressed but still living neurons due to altered signaling [1]. The living dead Amyotrophic lateral sclerosis (ALS), an age-related neurodegenerative disease, is characterized by the progressive loss of motor neurons. Historically, much of ALS...
August 18, 2026
This AI startup, which lists Nobel laureate David Baker among its co-founders, has announced a “world model” of a cell that can simulate both its natural state and responses to successive perturbations, potentially transforming biological research. Living in a simulation Simulating a living organism on a computer (in silico) has been a dream of both...
August 14, 2026
A massive human genetics study identified rare folliculin-interacting protein 1 (FNIP1) mutations associated with favorable metabolism and much lower cardiometabolic disease risk. Experiments in human liver cells and mice suggest a therapeutic route [1]. Longevity hidden in the genome For decades, aging researchers have hoped that human genetics might reveal genuine “longevity genes” whose altered...