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January 16, 2026
According to a new study, as many as 90% of Alzheimer’s cases can be attributed to “suboptimal” variants of the APOE gene. These results highlight the gene’s importance for Alzheimer’s prevention [1]. Three alleles of APOE A growing amount of research links Alzheimer’s disease to the gene APOE, which codes for apolipoprotein E [2]. This...
January 15, 2026
The last installment in our end-of-year series of expert roundups might be the least flashy, but it is arguably no less important than the previous ones dedicated to longevity biotech and geroscience. Public advocacy is a powerful lever. To quote Abraham Lincoln: “Public sentiment is everything. With it, nothing can fail; against it, nothing can...
January 13, 2026
2025 was a good year for geroscience, marked by rapid strides and critical milestones. Yet, the path wasn't always smooth: progress in some areas lagged, research hit dead ends, and familiar bottlenecks persisted. Against this backdrop, we asked five prominent geroscientists to share their perspectives on the highs and lows of 2025, along with their...
January 09, 2026
By inhibiting the aging-related enzyme 15-PGDH, scientists have shifted cartilage cells towards a healthier phenotype, leading to a significant improvement in a mouse model of osteoarthritis [1]. The hard-to-repair part Articular cartilage (the smooth, load-bearing cartilage on the ends of bones) doesn’t repair well with age or after injury [2], which is why osteoarthritis is...
January 06, 2026
How did the year 2025 turn out for longevity biotech? Was it surprising or more of the same? Exciting or disappointing? Was the progress fast-moving or excruciatingly slow? What should we expect in 2026? We asked five leading experts to weigh in. Where did longevity biotech exceed your expectations in 2025, and where did it...
January 05, 2026
Scientists have found that a single microbial species can blunt the negative effects of a high-fat diet due to the unique mix of lipids it produces [1]. They intend to identify its specific lipids in future work. Good neighbors The billions of gut microbes that we share our bodies with can profoundly influence our health....