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May 15, 2026
Scientists have found a way to drastically ramp up mouse immune responses to cancer along with flu and COVID-19 [1]. How to wake up the immune system Modern cancer immunotherapies only work for a minority of patients. The reason, broadly, is that many tumors are immunologically “cold”: they do not trigger, and/or actively suppress, the...
May 12, 2026
A new study suggests that GLP-1 receptor agonists do not affect muscle mass any more than weight loss caused by caloric restriction, and this appears to be true for strength as well [1]. What do we lose when we lose weight? GLP-1-based drugs, such as semaglutide and tirzepatide, have transformed obesity treatment. People on these...
May 08, 2026
Dr. Junyue Cao is a professor at the Rockefeller University, and his lab develops ultra-high-throughput single-cell technologies and applies them to the biology of aging. In a recent paper published in Science, his team used a technique called EasySci-ATAC to profile chromatin accessibility in about seven million cells from 21 mouse tissues across three ages,...
May 05, 2026
In a new study, the popular supplement creatine seemed to add to some of the beneficial effects of power training [1]. Trying the combination in older people Exercise might be the most potent anti-aging intervention known to humans, but with age, building strength and muscle mass becomes harder. Also, not all types of exercise are...
May 04, 2026
A new study has pit an advanced large language model against human physicians in tasks involving complex reasoning, treatment recommendations, and messy real-world patient records [1]. Testing a “thinking” model The dream of a ‘computer doctor’ has existed since at least 1959 [2], but until the recent rise of large language models, no computer program...
April 28, 2026
A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of obesity. In mice, the effect lasts for weeks, while its existence and duration in humans are to be determined [1]. The inflammation that stays Obesity is a chronic, relapsing condition linked to...