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June 27, 2025
Scientists have found that visceral fat and subcutaneous fat produce different responses to obesity in male mice and human patients and identified an important regulator of these processes [1]. The tale of the two fats It has been known that visceral fat, which accumulates around organs in the abdomen, and subcutaneous fat, which accumulates under...
June 25, 2025
Scientists have discovered that a rare mutation protects against Alzheimer’s disease by dampening a central inflammatory pathway. They recapitulated these results using a small molecule [1]. The woman who beat the odds For the last 40 years, scientists have been studying a massive extended family of about 6,000 people in and around Medellín, Colombia. Many...
June 20, 2025
Just several years ago, longevity conferences were few and far between. Today, there’s no shortage of them. Happening regularly around the globe, they foster scientific debate and showcase geroscience advances to the world while energetically discussing longevity biotech and regulations. However, one important subfield, working with public opinion and politicians, has been all but excluded...
June 17, 2025
By analyzing a large UK dataset, scientists have identified various financial behaviors that might point to dementia years before it leads to loss of financial capacity [1]. The money trail Alzheimer’s disease and related dementias remain a particularly hard nut for scientists to crack. One commonly mentioned problem is that dementia is usually diagnosed relatively...
June 13, 2025
A new study has lent more support to previous epidemiological data that ties the popular sugar substitute erythritol to elevated cardiovascular risk [1]. Deceptively sweet Sugar substitutes have been around for decades, and while some people have reported decreases in weight and blood glucose, a growing body of research suggests there might be some downsides...
June 10, 2025
Scientists have found that only about 1% of presented tumor antigens come from oncogenic mutations. The remaining 99%, previously overlooked, may offer better treatment targets [1]. Going after mutations Cancer arises from a series of mutations that drive abnormal cellular behaviors, such as runaway proliferation. Cancerous cells also normally present abnormal peptides on their surfaces...
