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Arkadi Mazin

Arkadi is a seasoned journalist and op-ed author with a passion for learning and exploration. His interests span from politics to science and philosophy. Having studied economics and international relations, he is particularly interested in the social aspects of longevity and life extension. He strongly believes that life extension is an achievable and noble goal that has yet to take its rightful place on the very top of our civilization’s agenda – a situation he is eager to change.

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Articles from this author

Human brain
A new study has shown that, unlike many other glucose-lowering drugs, metformin is regulated by the protein Ras1 in a specific subset of neurons, and when injected into the brain, even tiny doses of metformin can do the job [1]. The brain connection The safe and cheap anti-diabetes drug metformin has been in use for...
Viva Frontier Tower
In downtown San Francisco, an entire tower is becoming a hub for longevity, AI, crypto, and robotics. It just hosted its first longevity conference. How does a group conquer a big city? The longevity community unites tens of thousands of researchers, founders, and enthusiasts, but this is mostly done virtually. Things began to change after...
Older people walking
A massive new meta-analysis confirms that 10,000 daily steps are not required for most of the health benefits of walking. Around 7,000 seems to be the sweet spot [1]. A step in the right direction "10,000 steps a day" is some of the most frequently heard health advice. It is hard to say why this...
Finding the right drug
Scientists have creatively used large databases of existing FDA-approved drugs and electronic medical records to locate candidates that are potentially effective against Alzheimer’s [1]. New approaches needed Many previously discovered drugs may be effective beyond their original indications, but it is challenging to match them to new ones. Thankfully, ever-growing computing power, new data, and...
Scientists have created an AI model that stratifies Alzheimer’s patients into subgroups that progress slowly or rapidly. When applied to a real-world failed trial, it revealed a robust effect in the former subgroup [1]. Stratify and conquer Drugs don’t work for everyone equally. Unfortunately, clinical trials are not always able to account for that, which...
Blood vessel in bone
Scientists have developed a protocol for hematopoietic stem cell transplantation that reconstructs a healthy blood system and prevents blood cancers in old mice while also reducing toxicity [1]. The blood factory Hematopoietic stem cells (HSCs) work hard for our entire lives, producing vast numbers of various blood cells. As we age, this process, like many...

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