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November 13, 2026
A new study has found that increased production of serotonin by neurons in a particular brain region inhibits dopamine production and willingness to move, causing loss of activity. Killing serotonin-producing neurons reversed the effect [1]. Can’t or won’t? Physical activity tends to decline with age. As with many manifestations of aging, we tend to think...
November 10, 2026
A new study shows healthspan and lifespan increases in male mice following late-life treatment with vanadyl sulfate, a food-derived molecule marketed as an over-the-counter supplement [1]. Searching for vulnerabilities Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead,...
November 06, 2026
In a clinical trial, the supplement NOVOS Core was associated with significant improvements in artery function and systolic blood pressure. It is unknown which particular ingredients are responsible for the effect [1]. To the Core of the matter Led by Christian Heiss, Professor of Cardiovascular Medicine, researchers at the University of Surrey put NOVOS Core,...
November 03, 2026
A new study found that shrinking reserves of naive T cells weaken tumor recognition in male mice by middle age more than in females. Restoring thymic activity improved protection [1]. Do men lose anti-cancer defenses with age? CD8+ T cells are immune cells that can kill infected or cancerous cells. However, an individual T cell...
October 30, 2026
In a new study, late-life treatment with a three-element senolytic vaccine led to lower senescence markers and a 12% increase in median lifespan in female B6 mice. However, short-lived controls complicate the picture [1]. Helping the immune system kill “zombie cells” Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do...
October 27, 2026
One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and might have contributed to this edition’s practical, entrepreneurial, and forward-oriented spirit. We have already reported on the unprecedented panel where FDA named longevity a priority....