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September 03, 2025
A recent study investigated the roles of brown adipose tissue and a lipid-controlling hormone, 12,13-diHOME, in cardiac health. The researchers examined the molecular mechanisms behind 12,13-diHOME's effects on the hearts of aged mice [1]. The aging heart Aging leads to many cardiovascular system-related changes, which are connected to disruptions in Ca2+ metabolism [2]. Similarly, brown...
August 27, 2025
According to a study published by Cyclarity Therapeutics, its drug UDP-003 shows benefits in reversing the root cause of atherosclerotic plaques [1]. Fighting the root cause Many available medications address only disease symptoms in an effort to mitigate them. However, the real challenge is to identify the root cause of a problem and find ways...
August 20, 2025
In a recent study, researchers identified the critical role that lithium plays in brain health and the development of mild cognitive impairment and Alzheimer’s disease. Supplementing with a lithium salt called lithium orotate can reverse many of its cognitive decline-related changes on the molecular and cellular levels [1]. The road less traveled Understanding the underlying...
August 13, 2025
Researchers have recently published a review on how cannabis use among older adults impacts age-related conditions and longevity [1]. Cannabinoids and longevity In recent years, researchers have observed an increase in cannabis use among older adults, mostly for chronic conditions, such as arthritis, pain, sleep improvement, anxiety, and depressive symptoms. However, there is also a...
August 06, 2025
A recent study reported that long-term nicotine consumption had a positive impact on motor function in male mice. The beneficial effects were mediated by sphingolipid and NAD+ metabolism [1]. Two faces of tobacco smoking Smoking tobacco is widely considered detrimental to health for multiple good reasons, as it has been associated with increased risks of...
July 30, 2025
A recent study investigated senescence in mouse and human skeletal muscle tissue. The authors demonstrated that the antiviral drug maraviroc reduces senescence and improves muscle health in aged mice [1]. Aging muscle tissue Senescent cells are one of the hallmarks of aging. One of their key characteristics is the presence of the senescence-associated secretory phenotype...