Tag: Tau

Scientists have shown that aberrant metabolism of glycogen in neurons is linked to the accumulation of harmful tau protein. Caloric restriction, genetic interventions, and small molecules might help [1]. Glycogen and the brain Aberrant aggregation of microtubule-associated protein tau (MAPT), or simply tau protein, is a hallmark of several neurodegenerative diseases [2]. The most famous...

Boosting a key autophagy-related protein discourages a core component of Alzheimer's from taking hold, according to a study published in Aging Cell. Taking out the trash Autophagy is the maintenance process of the cell, in which autophagosomes engulf unwanted organelles and other material and fuse together with lysosomes to be digested. As these unwanted components...

A recent preprint paper from researchers at Sachi Bio has described how this company's technology can be used to alleviate brain inflammation in a mouse model. The problem of tau Along with the infamous amyloid beta, tau is well-known as a pathological factor in both Alzheimer's and regular aging [1]. The accumulation of tau with...

  One of the most common diseases in the world is herpes, as 50 to 80% of Americans have this illness. The herpes simplex virus, which causes cold sores, is normally transmitted through person-to-person contact. This illness leaves the patient with blisters clustered around the mouth. Gradually, the blisters pop and leave sores that take...

Researchers publishing in Alzheimer's and Dementia have published a correlation between the Alzheimer's-linked protein tau and another protein, bisecting N-acetylglucosamine (GlcNAc), which suggests its usefulness as a biomarker. The need for early prediction This paper begins with a note that to be effective, Alzheimer's treatment must begin before irrevocable neurodegeneration has already occurred [1]. Therefore,...

A group of researchers has confirmed the neuroprotective effect of blueberry extract and identified a possible mechanism of action that might facilitate drug development [1]. The delicious cure? Blueberries have long been on the list of "superfoods" that supposedly protect our health and maybe help us live a bit longer. Flavonoids, a class of plant-derived...