Tag: Ovaries

A recent review in the Journal of Ovarian Research summarizes current knowledge of the impact of various polyphenols on different aspects of ovarian aging. The researchers discuss that polyphenol supplementation could be used as an intervention to delay ovarian aging [1]. Every woman’s problem Ovarian aging and cessation of proper ovarian functioning precede aging in...

In Aging, researchers have published their discovery that three years of caloric restriction in rhesus macaques that are beginning to enter menopause slows their ovarian aging. Closer to people than mice The ovary is one of the first human organs to be seriously affected by aging, with the follicles becoming depleted long before most causes...

An investigation into transplanting human embryonic stem cells (hESC)-derived MSC-like cells (M cells) into the ovaries of cynomolgus monkeys suggests an extension of female reproductive span accompanied by a reduction in senescence-associated processes, such as inflammation, fibrosis, oxidative damage, and apoptosis [1]. Increasing healthspan by delaying menopause Aging of the female reproductive system precedes aging...

The researchers of a Nature Aging paper used multi-omics approaches to investigate cellular, molecular, and genetic drivers of human ovarian aging [1]. An early decline A decline in ovarian function occurs before a similar decline in other organs. Already in their mid-to-late thirties, women can experience symptoms such as fertility problems or increased frequency of...

In a new study, researchers tested the impact of the senolytic drug ABT-263 on the reproductive systems of old female mice. ABT-263 treatment did not rescue age-related changes in hormonal levels, further depleted ovarian reserves, and didn’t improve most of the tested signs of reproductive aging [1]. Not created equal Aging doesn’t seem to affect...

Recent research published in Immunity and Ageing suggests that chitosan can be used as a potential treatment to alleviate some of the aging processes in ovaries [1]. Quickly declining fertility Mother Nature has imposed some tough challenges on human females. They need to make the decision about motherhood sooner rather than later, as research has...