Tag: Neurodegenerative Diseases

Scientists have found a pathway that regulates protein aggregation, a cause of several age-related neurodegenerative diseases. United by abnormal protein aggregation Most neurodegenerative diseases are age-related, and many of them are similar in other ways. For instance, amyotrophic lateral sclerosis (ALS), Huntington’s disease, and Alzheimer’s disease have all been linked to abnormal protein aggregation [1],...

In a recent study, researchers identified the critical role that lithium plays in brain health and the development of mild cognitive impairment and Alzheimer’s disease. Supplementing with a lithium salt called lithium orotate can reverse many of its cognitive decline-related changes on the molecular and cellular levels [1]. The road less traveled Understanding the underlying...

Researchers have recently published a review on how cannabis use among older adults impacts age-related conditions and longevity [1]. Cannabinoids and longevity In recent years, researchers have observed an increase in cannabis use among older adults, mostly for chronic conditions, such as arthritis, pain, sleep improvement, anxiety, and depressive symptoms. However, there is also a...

In Aging, researchers have reported on how an increase in FGF21, a myokine that encourages muscle growth, impacts the progression of amyotrophic lateral sclerosis (ALS). Progressive and fatal ALS is an age-related disease that is characterized by the degeneration of motor neurons throughout the spinal cord and in the brain, leading to death by respiratory...

A recent preprint paper from researchers at Sachi Bio has described how this company's technology can be used to alleviate brain inflammation in a mouse model. The problem of tau Along with the infamous amyloid beta, tau is well-known as a pathological factor in both Alzheimer's and regular aging [1]. The accumulation of tau with...

A new publication in Nature Aging has used organoids and model mice to discover that senolytics may be effective treatments for neurodegeneration caused by long COVID. A link between COVID-19 and cellular senescence Post-acute infection syndromes (PAISes) are caused by a variety of viral and bacterial infections. The PAIS specific to the COVID-causing SARS-CoV-2, "long...