Lifespan Research Institute

Tag: Gut Microbiome

Scientists have found that a single microbial species can blunt the negative effects of a high-fat diet due to the unique mix of lipids it produces [1]. They intend to identify its specific lipids in future work. Good neighbors The billions of gut microbes that we share our bodies with can profoundly influence our health....
Scientists have given three types of beer to artificially aged male mice and recorded numerous beneficial effects, including improvements in microbiome diversity and lipid profiles [1]. Can alcohol be healthy? While it is firmly established that excessive alcohol consumption negatively impacts health, debates around moderate consumption are still ongoing. Some researchers suggest that the healthy...
Gut bacteria close up
In a recent study that included data from humans, mice, and cell culture experiments, researchers demonstrated that gut microbes and their metabolites can profoundly influence the senescence of endothelial cells. They also explored the molecular processes underlying these changes [1]. Senescence in the blood vessels Endothelial cells line the inner surfaces of blood vessels, and...
Intestines
In a recent study, lifelong, repeated microbiota transfer from young mice to old mice improves intestinal permeability, coordinative ability, and metabolic profiles while reducing pro-inflammatory responses [1]. Small in size, but mighty in impact Previous research has found that the composition and function of gut microbes (microbiota) changes as we age. These changes are linked...
Gut microbiome
A new study dives into a human-derived probiotic cocktail meant to protect against Alzheimer’s disease. The treatment improves gut health and reduces inflammation in mice [1]. The earlier, the better Early interventions to prevent or delay Alzheimer's disease might be a more feasible approach than reversing the disease when it is fully developed. However, such...
Gut bacteria inside
In Aging Cell, researchers have described how different combinations of gut bacteria impact muscle strength in mice. Expanding upon a known link The link between gut bacteria and health is well-documented, and multiple biomarkers have confirmed that a healthy gut leads to health elsewhere [1]. This is not just due to inflammation caused by pathogenic...