Tag: Bone

Researchers publishing in Nature Aging have discovered how Alzheimer's-related protein aggregates are also related to senescent cells and osteoporosis. Beyond the brain Why We Age: Loss of ProteostasisThe loss of proteostasis is the failure of the protein-building machinery of the cell and the accumulation of misfolded proteins, which is one of the root causes of...

Researchers publishing in Nature Aging have discovered that extracellular vesicles (EVs) derived from antler blastema progenitor cells (ABPCs) restore bone mass to rhesus macaques. Finding the most effective EVs In the world of rejuvenation research, EVs are nothing new. We have covered them extensively, as studies have repeatedly found benefits for the heart and effectiveness...

In Aging, researchers have described how a derivative of caffeic acid inhibits osteoclasts, the cells that break down bone. A modification of a tested compound We have recently published new information on what triggers the imbalance between bone-destroying osteoclasts and bone-building osteoblasts. This is a well-known problem with aging, and researchers around the world have...

Researchers have described a relationship between the NAD+ regulator CD38, mitochondrial function, and the gradual destruction of bone in Aging Cell. Inflammation up, bone mass down Nicotinamide Adenine Dinucleotide (NAD): Benefits and ResearchNicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. It is a dinucleotide, which means that it consists of two...

A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound Corylin is a compound that was first discovered in Psoralea corylifolia, a plant commonly used in Chinese traditional medicine. This is far from the first...

In Aging, researchers have published negative results on the long-term use of methylene blue and mitoquinone (MitoQ), two popular antioxidants, to sustain bone health in mice. Oxidative stress and bone health Previous work has found that oxidative stress, which is commonly associated with age-related disease and damage, is related to bone diseases. Substantial amounts of...