Category: News
João Pedro de Magalhães on the Ethics of Longevity
February 25, 2026
João Pedro de Magalhães, professor at the University of Birmingham, is known as a prominent geroscientist who has been in the field forever, enriching it with top-tier research. He is
Menopausal Hormone Therapy Does Not Increase Mortality
February 25, 2026
An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality [1]. A controversial therapy One of the first major changes that women undergo as
Thermogeneration by White Fat Could Be Used to Treat Obesity
February 24, 2026
Scientists have discovered that, like brown fat, white fat has a mechanism that burns fuel to produce heat. This effect could potentially be used to create weight loss drugs [1].
How a Sirtuin Protects Against Brain Diseases
February 23, 2026
In Aging Cell, researchers have explained how the sirtuin SIRT6 protects against proteostasis-related brain disorders by maintaining the function of nucleoli and limiting protein production. The nucleus and nucleoli A
AI Tool Sets New Standard in Diagnosing Rare Diseases
February 20, 2026
A new system, which consists of a large LLM and a network of agentic tools, outperformed several other models and human physicians [1]. Too rare to easily diagnose Rare diseases
A Circulating Inflammation Suppressor Decreases Mortality
February 19, 2026
Researchers publishing in Aging have used Mendelian randomization to conclude that the inflammatory factor IL6 causes increased mortality and that its circulating receptor, IL6R, decreases it. Looking for a proof
Lifetime Cognitive Enrichment Associated With Less Dementia
February 18, 2026
A recent study suggests that cognitive enrichment throughout life is associated with reduced dementia risk, and it has the potential to delay the onset of dementia and mild cognitive impairment
New Study Calculates Lifespan Gains From Five Popular Diets
February 17, 2026
Scientists have pitted five diets against each other to see which one is associated with more years of life gained [1]. The clash of the diets Unhealthy eating is recognized
Silencing Growth Hormone Has Strong Effects in Mouse Brains
February 16, 2026
Researchers have found that altering a growth hormone receptor in the brain adipose tissue of aged male mice slows their mental aging and allows them to perform far better on
Cellular Reprogramming Rescues Memory-Encoding Neurons
February 13, 2026
Scientists have applied partial reprogramming to memory-encoding neurons (engrams) and achieved memory improvements in Alzheimer’s models and wild-type mice [1]. Rejuvenating neurons Partial cellular reprogramming, which uses certain factors to
Creating CAR-T Cells Using Current Alzheimer’s Antibodies
February 12, 2026
A team of researchers has biologically engineered T cells with currently available Alzheimer’s drugs in order to directly attack the characteristic amyloid plaques of Alzheimer’s disease. Building on the current
Young Microbes Rejuvenate Intestinal Function in Mice
February 11, 2026
Transferring microbiota from young to aged mice helped to restore molecular signaling necessary for proper intestinal function and improved the regenerative capacity of intestinal stem cells [1]. Everyday companions Bacteria,
Sleep Deprivation Affects Cognition via Myelin Loss
February 10, 2026
A new study links sleep loss to the thinning of the myelin layer, which slows signal transmission in axons. Restoring cholesterol homeostasis reverses the damage [1]. Sleep loss hurts myelin
Restoring the Strength of Natural Killer Cells
February 9, 2026
In Aging Cell, researchers have described why older natural killer (NK) cells lose their ability to eliminate harmful cells and a potential treatment for this decline. Judgment and ability At
First Human Cellular Reprogramming Trial Cleared by the FDA
February 6, 2026
Life Biosciences has announced that its trial of cellular reprogramming aimed at two age-related vision diseases has received a go-ahead from the FDA. We spoke with the company’s CSO to
João Pedro de Magalhães on the Ethics of Longevity
February 25, 2026
João Pedro de Magalhães, professor at the University of Birmingham, is known as a prominent geroscientist who has been in the field forever, enriching it with top-tier research. He is also a skilled longevity advocate who has long taken interest in the ethics of longevity, first
Menopausal Hormone Therapy Does Not Increase Mortality
February 25, 2026
An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality [1]. A controversial therapy One of the first major changes that women undergo as they age is menopause, which usually occurs between 45 and 55 years of age. Menopause not
Thermogeneration by White Fat Could Be Used to Treat Obesity
February 24, 2026
Scientists have discovered that, like brown fat, white fat has a mechanism that burns fuel to produce heat. This effect could potentially be used to create weight loss drugs [1]. Central heating Cells use energy to power various cellular processes, with heat being a byproduct. However,
How a Sirtuin Protects Against Brain Diseases
February 23, 2026
In Aging Cell, researchers have explained how the sirtuin SIRT6 protects against proteostasis-related brain disorders by maintaining the function of nucleoli and limiting protein production. The nucleus and nucleoli A cell’s nucleus has one or more nucleoli, where the cell does its critical work of synthesizing
AI Tool Sets New Standard in Diagnosing Rare Diseases
February 20, 2026
A new system, which consists of a large LLM and a network of agentic tools, outperformed several other models and human physicians [1]. Too rare to easily diagnose Rare diseases can be notoriously hard to diagnose. Patients average over 5 years to receive a correct diagnosis,
A Circulating Inflammation Suppressor Decreases Mortality
February 19, 2026
Researchers publishing in Aging have used Mendelian randomization to conclude that the inflammatory factor IL6 causes increased mortality and that its circulating receptor, IL6R, decreases it. Looking for a proof of danger Chronic, age-related inflammation (inflammaging) is very well-known to be closely connected to negative age-related
Lifetime Cognitive Enrichment Associated With Less Dementia
February 18, 2026
A recent study suggests that cognitive enrichment throughout life is associated with reduced dementia risk, and it has the potential to delay the onset of dementia and mild cognitive impairment by five to seven years [1]. Cognitive stimulation Engagement in cognitively stimulating activities has been linked
New Study Calculates Lifespan Gains From Five Popular Diets
February 17, 2026
Scientists have pitted five diets against each other to see which one is associated with more years of life gained [1]. The clash of the diets Unhealthy eating is recognized as a globally leading cause of death [2]. Surprisingly, few studies have actually evaluated the gains
Silencing Growth Hormone Has Strong Effects in Mouse Brains
February 16, 2026
Researchers have found that altering a growth hormone receptor in the brain adipose tissue of aged male mice slows their mental aging and allows them to perform far better on cognitive tests. Growth signaling is not necessarily good The axis of growth hormone and insulin-like growth
Cellular Reprogramming Rescues Memory-Encoding Neurons
February 13, 2026
Scientists have applied partial reprogramming to memory-encoding neurons (engrams) and achieved memory improvements in Alzheimer’s models and wild-type mice [1]. Rejuvenating neurons Partial cellular reprogramming, which uses certain factors to rejuvenate cells while maintaining their identity) has shown promise across various conditions and cell types, including
Creating CAR-T Cells Using Current Alzheimer’s Antibodies
February 12, 2026
A team of researchers has biologically engineered T cells with currently available Alzheimer’s drugs in order to directly attack the characteristic amyloid plaques of Alzheimer’s disease. Building on the current paradigm Most Alzheimer’s treatments used in the clinic are -mabs, monoclonal antibodies that are designed to
Young Microbes Rejuvenate Intestinal Function in Mice
February 11, 2026
Transferring microbiota from young to aged mice helped to restore molecular signaling necessary for proper intestinal function and improved the regenerative capacity of intestinal stem cells [1]. Everyday companions Bacteria, viruses, and other microbes are well-known as agents that cause disease and should be avoided. However,
Sleep Deprivation Affects Cognition via Myelin Loss
February 10, 2026
A new study links sleep loss to the thinning of the myelin layer, which slows signal transmission in axons. Restoring cholesterol homeostasis reverses the damage [1]. Sleep loss hurts myelin Sleep quality is a strong extrinsic determinant of longevity [2]. Not only does sleep loss affect
Restoring the Strength of Natural Killer Cells
February 9, 2026
In Aging Cell, researchers have described why older natural killer (NK) cells lose their ability to eliminate harmful cells and a potential treatment for this decline. Judgment and ability At the cellular level, there is no due process. Natural killer (NK) cells judge other cells’ guilt
First Human Cellular Reprogramming Trial Cleared by the FDA
February 6, 2026
Life Biosciences has announced that its trial of cellular reprogramming aimed at two age-related vision diseases has received a go-ahead from the FDA. We spoke with the company’s CSO to get more details. Life Biosciences, the biotech company based on Harvard professor David Sinclair’s research into