Category: News
Inducing NREM-Like Neuronal Patterns Mimics Sleep Benefits
June 11, 2026
Scientists have “faked” sleep in mice by artificially creating the on/off neuronal firing pattern similar to that seen in non-REM sleep. This produced sleep-like effects, including improved learning memory [1].
The Immune System Maintains the Microbiome
June 10, 2026
In a recent paper, researchers have proposed that the immune system and immune surveillance play a central role in maintaining microbial composition throughout life by suppressing microbial proliferation and that
How Gut Bacteria Affect Lung Fibrosis
June 9, 2026
In Aging Cell, researchers have described how a strain of Lactobacillus gut bacteria sends chemical signals that enter the bloodstream and decrease fibrosis in the lungs. The gut-lung axis The
Fighting Parkinson’s by Restoring Protein Degradation
June 8, 2026
Researchers have explained how a protein found in both yeast and humans facilitates the destruction of the core protein responsible for Parkinson’s disease. An aggregate that impairs clearance The loss
Neurons’ Protein Disposal Trick Offers Alzheimer’s Insights
June 5, 2026
According to a new study, a special protein disposal system, currently found only in neurons, is linked to central hallmarks of Alzheimer’s disease [1]. The membranal proteasome Alzheimer’s disease is
Preventing Load-Induced Arthritis at the Cellular Level
June 4, 2026
Researchers have discovered that the osteoarthritis-inducing effects of excessive mechanical stress can be mitigated by increasing miR-330, a key regulator in cartilage and bone cells. Backbreaking labor is exactly that
The Thalion Initiative: A New Non-Profit With Big Ambitions
June 2, 2026
The longevity field remains small and starved for resources, especially the subfield devoted to the fundamental biology of aging, despite near-universal agreement that solving aging requires understanding it first. With
Rejuvenation Roundup May 2026
June 1, 2026
Approaches that modify the processes of aging at their roots have gone well beyond basic research and into therapies intended for the clinic within the next few years. Here’s how
Harvard Publishes a Longevity Report for the General Public
May 29, 2026
The report, titled “Pathways to Longevity”, introduces several important longevity concepts to the general reader and is another sign that the field is coming of age and entering the mainstream.
A Better Algorithm for Predicting How Cells Behave
May 28, 2026
In a preprint published in arXiv, researchers from Altos Labs have described a machine learning algorithm that performs end-to-end prediction of how cells’ gene expression will respond to interventions. The
Early Cancer Cells Change Their Surroundings to Form Tumors
May 28, 2026
Scientists have demonstrated how cancer cells influence neighboring cells to create a favorable niche for the tumor to grow. This can inform future early-stage cancer therapies [1]. Cancer is a
Cardiovascular Health During the Menopausal Transition
May 27, 2026
A recent study compared premenopausal, perimenopausal, and postmenopausal women’s cardiovascular health. Perimenopausal women had about twice the odds of having a poor overall score when compared with premenopausal women, after
Tau Protein Is Crucial for Encoding Long-Term Memory
May 26, 2026
Scientists have uncovered an unexpected function of the tau protein, which is mostly known for its role in Alzheimer’s and related disorders: helping encode long-term memory. This can inform novel
How Omega-3 Fatty Acids May Alleviate Kidney Disease
May 25, 2026
Researchers have discovered the role of cellular senescence in the interaction between omega-3 polyunsaturated fatty acids (PUFAs) and chronic kidney disease (CKD). Previous mixed results Several clinical trials have found
Mitochondrial Aging Linked to Losing Crucial Membrane Lipid
May 22, 2026
Scientists have found that the levels of phosphatidylcholine, the most abundant lipid in mitochondrial membranes, decline with age, driving mitochondrial aging in worms and possibly humans. Supplementing the lipid helped
Inducing NREM-Like Neuronal Patterns Mimics Sleep Benefits
June 11, 2026
Scientists have “faked” sleep in mice by artificially creating the on/off neuronal firing pattern similar to that seen in non-REM sleep. This produced sleep-like effects, including improved learning memory [1]. Can sleep be emulated? Getting proper amounts and quality of sleep is one of the best
The Immune System Maintains the Microbiome
June 10, 2026
In a recent paper, researchers have proposed that the immune system and immune surveillance play a central role in maintaining microbial composition throughout life by suppressing microbial proliferation and that aging weakens these processes [1]. Lifelong companions Aging leads to the deterioration of the organs and
How Gut Bacteria Affect Lung Fibrosis
June 9, 2026
In Aging Cell, researchers have described how a strain of Lactobacillus gut bacteria sends chemical signals that enter the bloodstream and decrease fibrosis in the lungs. The gut-lung axis The gut-brain axis, the term for how the intestines and nervous system interact, is well-known to many
Fighting Parkinson’s by Restoring Protein Degradation
June 8, 2026
Researchers have explained how a protein found in both yeast and humans facilitates the destruction of the core protein responsible for Parkinson’s disease. An aggregate that impairs clearance The loss of proteostasis involves the growing inability of cells’ lysosomes to clear toxic, misfolded proteins, which gradually
Neurons’ Protein Disposal Trick Offers Alzheimer’s Insights
June 5, 2026
According to a new study, a special protein disposal system, currently found only in neurons, is linked to central hallmarks of Alzheimer’s disease [1]. The membranal proteasome Alzheimer’s disease is defined in part by two protein aggregates in the brain: amyloid-β plaques outside cells, and tangles
Preventing Load-Induced Arthritis at the Cellular Level
June 4, 2026
Researchers have discovered that the osteoarthritis-inducing effects of excessive mechanical stress can be mitigated by increasing miR-330, a key regulator in cartilage and bone cells. Backbreaking labor is exactly that It has been long-held conventional wisdom that a lifetime of heavy physical labor leads to the
The Thalion Initiative: A New Non-Profit With Big Ambitions
June 2, 2026
The longevity field remains small and starved for resources, especially the subfield devoted to the fundamental biology of aging, despite near-universal agreement that solving aging requires understanding it first. With VCs looking for clinical successes and state funding drying up for many projects, some enthusiasts are
Rejuvenation Roundup May 2026
June 1, 2026
Approaches that modify the processes of aging at their roots have gone well beyond basic research and into therapies intended for the clinic within the next few years. Here’s how the field has advanced in May. Team and activities The Longevity Investor Network Looks Back at
Harvard Publishes a Longevity Report for the General Public
May 29, 2026
The report, titled “Pathways to Longevity”, introduces several important longevity concepts to the general reader and is another sign that the field is coming of age and entering the mainstream. People do want to live longer From time to time, Harvard Health Publishing issues Special Health
A Better Algorithm for Predicting How Cells Behave
May 28, 2026
In a preprint published in arXiv, researchers from Altos Labs have described a machine learning algorithm that performs end-to-end prediction of how cells’ gene expression will respond to interventions. The need for prediction Simulating biological processes on a computer is an incredibly difficult task. While advanced
Early Cancer Cells Change Their Surroundings to Form Tumors
May 28, 2026
Scientists have demonstrated how cancer cells influence neighboring cells to create a favorable niche for the tumor to grow. This can inform future early-stage cancer therapies [1]. Cancer is a disease of aging. With the exception of childhood cancers, most of which stem from inherited genetic
Cardiovascular Health During the Menopausal Transition
May 27, 2026
A recent study compared premenopausal, perimenopausal, and postmenopausal women’s cardiovascular health. Perimenopausal women had about twice the odds of having a poor overall score when compared with premenopausal women, after adjusting for age [1]. Menopausal health decline The menopausal transition, and the associated changes in hormonal
Tau Protein Is Crucial for Encoding Long-Term Memory
May 26, 2026
Scientists have uncovered an unexpected function of the tau protein, which is mostly known for its role in Alzheimer’s and related disorders: helping encode long-term memory. This can inform novel approaches that target tau [1]. In sickness and in health Tau is a protein found mainly
How Omega-3 Fatty Acids May Alleviate Kidney Disease
May 25, 2026
Researchers have discovered the role of cellular senescence in the interaction between omega-3 polyunsaturated fatty acids (PUFAs) and chronic kidney disease (CKD). Previous mixed results Several clinical trials have found that taking omega-3 PUFAs has benefits for older people. One study found that it reduces the
Mitochondrial Aging Linked to Losing Crucial Membrane Lipid
May 22, 2026
Scientists have found that the levels of phosphatidylcholine, the most abundant lipid in mitochondrial membranes, decline with age, driving mitochondrial aging in worms and possibly humans. Supplementing the lipid helped in an in vitro experiment [1]. What drives mitochondrial aging? Mitochondria are the cell’s energy-generating organelles,