Category: News
Transplanted Immune Cells Donate Mitochondria to Neighbors
September 22, 2026
According to a new study using a mouse model of a rare disease, transplanted immune cells donate their mitochondria to neighboring donor cells, improving energy production and rescuing function [1].
Intermittent Fasting Shows Promise in a Huntington’s Trial
September 21, 2026
In a pilot study, patients engaging in intermittent fasting demonstrated improvements in Huntington’s disease, a neurodegenerative condition currently considered untreatable. However, the study’s size and limitations call for more research
Thymus Grafts Grow in Mouse Spleens, Restoring Immunity
September 18, 2026
In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1]. Growing one organ inside another
Clearing Damaged Mitochondria to Fight Skin Photoaging
September 17, 2026
Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by
An Entirely New Target for Fighting Senescence
September 15, 2026
Researchers have established how a protein that is nearly absent in the literature, PTCHD4, is linked to cellular senescence. Very little previous work In most papers, after a customary discussion
Mitochondrial Performance May Strongly Influence Learning
September 14, 2026
A team of researchers has discovered that mitochondrial health and location may be critical to why cognitive plasticity decreases with age. Old mammals and new tricks The adage ‘you can’t
Lung Fibrosis Drug Lowers Biological Age Estimates
September 11, 2026
Six different aging clocks detected younger blood protein profiles in patients taking the experimental lung-fibrosis drug rentosertib. This suggests possible anti-aging effects, but separating those from the narrower benefits of
Calcium Mishandling Contributes to Muscle Loss
September 10, 2026
Researchers have discovered and explained how calcium mishandling in muscle cells leads to long-term muscle weakness in older people. Calcium is not just for bones Skeletal muscle cells use calcium
Comparing the Responsiveness of Epigenetic Aging Biomarkers
September 9, 2026
In a recent study, researchers have evaluated how responsive several DNA methylation (DNAm) biomarkers are to a range of longevity interventions [1]. Waiting too long Testing lifespan-extending interventions in humans
Late-Life GLP-1 Treatment Increases Lifespan in Female Mice
September 8, 2026
In a new study, semaglutide given late in life increased median lifespan in female mice by more than 12% and improved various health markers. Semaglutide’s effect possibly went beyond caloric
Mice With Growth Hormone Halted in Middle Age Live Longer
September 7, 2026
Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Growth but diabetes Growth hormone affects the metabolism of
The Last Generation to Die: Interview With Tim Maupin
September 3, 2026
Filmmaker Tim Maupin has spent a number of years developing The Last Generation to Die, a near-future film about what happens when the first true rejuvenation technologies arrive and who
Rejuvenation Roundup August 2026
September 1, 2026
Properly untangling aging means untangling its various counterbalances, sometimes on the individual level. Here’s what’s been investigated this month. Interviews Wei-Wu He: People Should Become the CEOs of Their Own
A Mechanistic Explanation for SIRT1’s Effects
August 31, 2026
Researchers have found that the sirtuin SIRT1 stabilizes the human genome by suppressing retrotransposition, which occurs when parts of the genome transcribe themselves onto other parts. When DNA modifies itself
Michael Snyder: We Need to Track Health, Not Disease
August 28, 2026
Michael Snyder, Director of the Center for Genomics and Personalized Medicine at Stanford University, is obsessed with health-tracking wearables. During our interview, he wore four wrist-worn devices – watches and
Transplanted Immune Cells Donate Mitochondria to Neighbors
September 22, 2026
According to a new study using a mouse model of a rare disease, transplanted immune cells donate their mitochondria to neighboring donor cells, improving energy production and rescuing function [1]. Here, have some mitochondria Friedreich’s ataxia is a rare genetic disease in which deficiency in the
Intermittent Fasting Shows Promise in a Huntington’s Trial
September 21, 2026
In a pilot study, patients engaging in intermittent fasting demonstrated improvements in Huntington’s disease, a neurodegenerative condition currently considered untreatable. However, the study’s size and limitations call for more research [1]. Fast to survive Huntington’s disease is an inherited, progressive neurodegenerative disorder caused by an expansion
Thymus Grafts Grow in Mouse Spleens, Restoring Immunity
September 18, 2026
In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1]. Growing one organ inside another The thymus is a small but crucial organ, where T cells mature to become the backbone
Clearing Damaged Mitochondria to Fight Skin Photoaging
September 17, 2026
Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by restoring their cells’ ability to get rid of their own damaged mitochondria (mitophagy). Wrinkles are only
An Entirely New Target for Fighting Senescence
September 15, 2026
Researchers have established how a protein that is nearly absent in the literature, PTCHD4, is linked to cellular senescence. Very little previous work In most papers, after a customary discussion of the mechanics of cellular senescence and current methods of handling it and its repercussions, the
Mitochondrial Performance May Strongly Influence Learning
September 14, 2026
A team of researchers has discovered that mitochondrial health and location may be critical to why cognitive plasticity decreases with age. Old mammals and new tricks The adage ‘you can’t teach an old dog new tricks’ is true across a wide variety of organisms; neural plasticity
Lung Fibrosis Drug Lowers Biological Age Estimates
September 11, 2026
Six different aging clocks detected younger blood protein profiles in patients taking the experimental lung-fibrosis drug rentosertib. This suggests possible anti-aging effects, but separating those from the narrower benefits of treating fibrosis remains a challenge [1]. The AI-developed drug Many drugs developed for particular diseases act
Calcium Mishandling Contributes to Muscle Loss
September 10, 2026
Researchers have discovered and explained how calcium mishandling in muscle cells leads to long-term muscle weakness in older people. Calcium is not just for bones Skeletal muscle cells use calcium ions to control how and when they contract. This activity is modulated by CaMKII, a protein
Comparing the Responsiveness of Epigenetic Aging Biomarkers
September 9, 2026
In a recent study, researchers have evaluated how responsive several DNA methylation (DNAm) biomarkers are to a range of longevity interventions [1]. Waiting too long Testing lifespan-extending interventions in humans has a major problem: it can take many years, or even decades, to see results. Nobody
Late-Life GLP-1 Treatment Increases Lifespan in Female Mice
September 8, 2026
In a new study, semaglutide given late in life increased median lifespan in female mice by more than 12% and improved various health markers. Semaglutide’s effect possibly went beyond caloric restriction [1]. Old mice, new drugs GLP-1 receptor agonists, which act on a hormone that regulates
Mice With Growth Hormone Halted in Middle Age Live Longer
September 7, 2026
Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Growth but diabetes Growth hormone affects the metabolism of fats (lipids), increasing the levels of circulating fatty acids while increasing insulin-like growth factor 1 (IGF-1)
The Last Generation to Die: Interview With Tim Maupin
September 3, 2026
Filmmaker Tim Maupin has spent a number of years developing The Last Generation to Die, a near-future film about what happens when the first true rejuvenation technologies arrive and who gets left behind. The project has now reached the top 65 of the Future Vision XPrize,
Rejuvenation Roundup August 2026
September 1, 2026
Properly untangling aging means untangling its various counterbalances, sometimes on the individual level. Here’s what’s been investigated this month. Interviews Wei-Wu He: People Should Become the CEOs of Their Own Health: Wei-Wu He is an unusual combination of scientist and businessman, and his current company focuses
A Mechanistic Explanation for SIRT1’s Effects
August 31, 2026
Researchers have found that the sirtuin SIRT1 stabilizes the human genome by suppressing retrotransposition, which occurs when parts of the genome transcribe themselves onto other parts. When DNA modifies itself Long interspersed elements-1 (LINE-1) have existed in organisms’ genomes, including our own, for well over a
Michael Snyder: We Need to Track Health, Not Disease
August 28, 2026
Michael Snyder, Director of the Center for Genomics and Personalized Medicine at Stanford University, is obsessed with health-tracking wearables. During our interview, he wore four wrist-worn devices – watches and bands – and two rings. He is convinced that these small but powerful gadgets will help