Category: News
Young Microbes Rejuvenate Intestinal Function in Mice
February 11, 2026
Transferring microbiota from young to aged mice helped to restore molecular signaling necessary for proper intestinal function and improved the regenerative capacity of intestinal stem cells [1]. Everyday companions Bacteria,
Sleep Deprivation Affects Cognition via Myelin Loss
February 10, 2026
A new study links sleep loss to the thinning of the myelin layer, which slows signal transmission in axons. Restoring cholesterol homeostasis reverses the damage [1]. Sleep loss hurts myelin
Restoring the Strength of Natural Killer Cells
February 9, 2026
In Aging Cell, researchers have described why older natural killer (NK) cells lose their ability to eliminate harmful cells and a potential treatment for this decline. Judgment and ability At
First Human Cellular Reprogramming Trial Cleared by the FDA
February 6, 2026
Life Biosciences has announced that its trial of cellular reprogramming aimed at two age-related vision diseases has received a go-ahead from the FDA. We spoke with the company’s CSO to
Increasing Senolytic Effectiveness by Stressing Mitochondria
February 5, 2026
Researchers publishing in Nature Aging have described how mitochondrial stress is a key part of why senolytics are effective. Finding targeted effectiveness The researchers began this study by summarizing senescent
Association Between Vitamins and Slower Biological Aging
February 4, 2026
A recent study analyzed data from over 15,000 participants and their intake of 11 vitamins, and the results suggested that higher vitamin intake, particularly of Vitamins C and B2, is
Weight Training Load Doesn’t Affect Muscle Mass or Strength
February 3, 2026
A new study suggests that, if sets are taken close to failure, the amount of weight on the bar does not determine muscle growth. However, individual differences in muscle-building ability
Rejuvenation Roundup January 2026
February 2, 2026
2026 has kicked off with several key research insights, and we’ve taken a look at the state of the industry and how rejuvenation biotechnology is moving forward. Here’s what’s been
CRISPR-Based Screen Reveals Possible Anti-Tau Mechanism
January 30, 2026
Using an ingenious CRISPR-based screening technique, scientists have found a protein that tags tau for degradation and is more strongly expressed in tau-resilient neurons [1]. Some neurons are more equal
Engineered Extracellular Vesicles Reduce Arrhythmia in Rats
January 29, 2026
In Nature Communications, researchers have described how small extracellular vesicles (sEVs) fused with plasma membrane proteins successfully treated heart arrhythmia in a rat model. Why do people need pacemakers? In
Shingles Vaccination Is Associated With Slower Aging
January 28, 2026
An analysis of over 3800 older adults found that shingles vaccination is associated with lower inflammation scores, slower epigenetic and transcriptomic aging, and a lower composite biological aging score [1].
Rapamycin Protects Immune Cells by Reducing DNA Damage
January 27, 2026
A new study from the Universities of Oxford and Nottingham has uncovered a potential new mechanism by which rapamycin counters immunosenescence. Rather than increasing autophagy or reducing protein synthesis, the
Using Placental Cells to Test Anti-Aging Compounds
January 26, 2026
Researchers publishing in Aging Cell have discovered that cells derived from the human placenta may be useful in estimating the effects of potential anti-aging treatments. A seemingly odd choice Of
Exercise Variety Is Associated With Lower Mortality Risk
January 23, 2026
A new study links exercise variety, defined as regularly engaging in several types of physical activity, to significantly lower all-cause mortality. Exercise amount matters as well, but the effect plateaus
How Senescent Astrocytes Don’t Support Neurons
January 22, 2026
Resesarchers have found that thrombospondin-1 (TSP-1), a compound that is critical in growing brain synapses, is secreted by normal astrocytes but not senescent ones. Senescence is harmful to the brain
Young Microbes Rejuvenate Intestinal Function in Mice
February 11, 2026
Transferring microbiota from young to aged mice helped to restore molecular signaling necessary for proper intestinal function and improved the regenerative capacity of intestinal stem cells [1]. Everyday companions Bacteria, viruses, and other microbes are well-known as agents that cause disease and should be avoided. However,
Sleep Deprivation Affects Cognition via Myelin Loss
February 10, 2026
A new study links sleep loss to the thinning of the myelin layer, which slows signal transmission in axons. Restoring cholesterol homeostasis reverses the damage [1]. Sleep loss hurts myelin Sleep quality is a strong extrinsic determinant of longevity [2]. Not only does sleep loss affect
Restoring the Strength of Natural Killer Cells
February 9, 2026
In Aging Cell, researchers have described why older natural killer (NK) cells lose their ability to eliminate harmful cells and a potential treatment for this decline. Judgment and ability At the cellular level, there is no due process. Natural killer (NK) cells judge other cells’ guilt
First Human Cellular Reprogramming Trial Cleared by the FDA
February 6, 2026
Life Biosciences has announced that its trial of cellular reprogramming aimed at two age-related vision diseases has received a go-ahead from the FDA. We spoke with the company’s CSO to get more details. Life Biosciences, the biotech company based on Harvard professor David Sinclair’s research into
Increasing Senolytic Effectiveness by Stressing Mitochondria
February 5, 2026
Researchers publishing in Nature Aging have described how mitochondrial stress is a key part of why senolytics are effective. Finding targeted effectiveness The researchers began this study by summarizing senescent cells and the senolytics created to eliminate them. They noted that few attempts have been made
Association Between Vitamins and Slower Biological Aging
February 4, 2026
A recent study analyzed data from over 15,000 participants and their intake of 11 vitamins, and the results suggested that higher vitamin intake, particularly of Vitamins C and B2, is associated with slower biological aging [1]. Beneficial molecules One of the easiest and most accessible ways
Weight Training Load Doesn’t Affect Muscle Mass or Strength
February 3, 2026
A new study suggests that, if sets are taken close to failure, the amount of weight on the bar does not determine muscle growth. However, individual differences in muscle-building ability appear to be real [1]. How should we train? Muscle mass and strength are among the
Rejuvenation Roundup January 2026
February 2, 2026
2026 has kicked off with several key research insights, and we’ve taken a look at the state of the industry and how rejuvenation biotechnology is moving forward. Here’s what’s been done in January. Advocacy and Analysis Longevity Biotech in 2025: The Expert Roundup: How did the
CRISPR-Based Screen Reveals Possible Anti-Tau Mechanism
January 30, 2026
Using an ingenious CRISPR-based screening technique, scientists have found a protein that tags tau for degradation and is more strongly expressed in tau-resilient neurons [1]. Some neurons are more equal than others The accumulation of tau protein fibrils in neurons is a hallmark of Alzheimer’s and
Engineered Extracellular Vesicles Reduce Arrhythmia in Rats
January 29, 2026
In Nature Communications, researchers have described how small extracellular vesicles (sEVs) fused with plasma membrane proteins successfully treated heart arrhythmia in a rat model. Why do people need pacemakers? In a healthy heart, the sinoatrial node (SAN) serves as a natural regulator, commanding the heart to
Shingles Vaccination Is Associated With Slower Aging
January 28, 2026
An analysis of over 3800 older adults found that shingles vaccination is associated with lower inflammation scores, slower epigenetic and transcriptomic aging, and a lower composite biological aging score [1]. Beneficial side effects Vaccines are developed to prevent specific diseases, such as polio, measles, hepatitis, and
Rapamycin Protects Immune Cells by Reducing DNA Damage
January 27, 2026
A new study from the Universities of Oxford and Nottingham has uncovered a potential new mechanism by which rapamycin counters immunosenescence. Rather than increasing autophagy or reducing protein synthesis, the effect appears to involve directly reducing DNA damage burden in immune cells [1]. How can this
Using Placental Cells to Test Anti-Aging Compounds
January 26, 2026
Researchers publishing in Aging Cell have discovered that cells derived from the human placenta may be useful in estimating the effects of potential anti-aging treatments. A seemingly odd choice Of all the organs in the body, the placenta may be the least concerning with regards to
Exercise Variety Is Associated With Lower Mortality Risk
January 23, 2026
A new study links exercise variety, defined as regularly engaging in several types of physical activity, to significantly lower all-cause mortality. Exercise amount matters as well, but the effect plateaus quickly [1]. How exactly is it good for you? “Exercise is good for you” is a
How Senescent Astrocytes Don’t Support Neurons
January 22, 2026
Resesarchers have found that thrombospondin-1 (TSP-1), a compound that is critical in growing brain synapses, is secreted by normal astrocytes but not senescent ones. Senescence is harmful to the brain It is well-known that cellular senescence causes brain damage and impairment. The SAMP8 mouse, which is