Category: News
An Astrocytic Factor Slows Whole-Body Aging in Mice
October 29, 2026
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice. A factor from a well-known family FGFs are
Rejuvenation Factor Extends Lifespan and Healthspan in Mice
October 28, 2026
A recent study identified SRSF1, an RNA-processing and splicing factor, as a molecule with geroprotective potential. Inducing SRSF1 expression rejuvenated human cells in vitro, extended lifespan, and significantly reduced frailty
ARDD 2026: Traditional Biology to AI-Driven Breakthroughs
October 27, 2026
One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and
The Regulatory Bottleneck in Aging Biology
October 26, 2026
Researchers are developing biomedical repair therapies to address multiple age-related diseases at once, yet they are forced to put them through regulatory pathways built for single-disease drugs. The result is
Laura Minquini on the Quest for Female Longevity
October 23, 2026
Laura Minquini is not a scientist, but that hasn’t stopped her from joining the front lines of the war on aging: specifically, female reproductive aging. Several years ago, after a
How Some Neuronal Cilia May Affect the Whole Body
October 22, 2026
A team of researchers has written a paper with a surprising finding: that many of the benefits of caloric restriction and increased NAD+ may be due to their effects on
AI Extracts Broader Health Insights From Routine CT Scans
October 20, 2026
A new study suggests that CT scans can provide information about a wide range of conditions, including some not typically diagnosed through imaging. Direct comparison with human radiologists is the
An RNA Regulator Mitigates Senescence in Blood Vessels
October 19, 2026
Researchers publishing in Aging Cell have found that the regulatory protein MTR4 fights DNA damage in the blood vessel lining but decreases with aging. Vulnerable by nature This paper begins
Blocking STING Helps Preserve Bone in Aging Mice
October 16, 2026
A new study links STING-mediated signals from marrow fat cells to inflammation and declining NAD⁺ levels in bone-forming cells. Interrupting this pathway helped preserve aging bone [1]. Making old bones
Making SIRT1 and NAD+ Therapies Work in People
October 15, 2026
Reviewers publishing in Biology have elucidated SIRT1 functional reserve as an aspect of aging, describing how its depletion is an upstream cause of age-related disorders at the cellular level and
Menopausal Serum Protein Changes May Predict Brain Health
October 14, 2026
A recent analysis of serum protein changes identified 16 proteins related to inflammatory, synaptic, metabolic, and Alzheimer’s disease processes whose levels change during the menopausal transition [1]. These changes were
Low-Fat Vegan Diet Shows Benefits in Type 2 Diabetes
October 13, 2026
A human trial found that even without caloric restriction, a low-fat, plant-based diet improved blood sugar control, reduced liver fat, and lowered the quantity of advanced glycation end products (AGEs)
An Anti-Senescence Gene May Fight Spinal Disc Deterioration
October 12, 2026
In Aging Cell, a team of researchers has described how a little-known gene, ZNF865, has a significant influence on back pain through the regulation of cellular senescence. Lower back pain
Gut Bacteria Molecule Slows Atherosclerosis in Mice
October 9, 2026
A new study highlights a fatty acid produced by a particular genus of bacteria as a “natural statin,” suggesting a new way of treating atherosclerosis [1]. Bacteria and cholesterol Atherosclerosis
Untangling Differences in Senescent Cellular Signaling
October 8, 2026
In Aging, researchers have described the differences between the secretions of cells driven senescent through a cancer gene and cells that stopped proliferating due to p16 expression. A difference of
An Astrocytic Factor Slows Whole-Body Aging in Mice
October 29, 2026
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice. A factor from a well-known family FGFs are signaling molecules that share structural and functional commonalities and play crucial roles in biology, including neural
Rejuvenation Factor Extends Lifespan and Healthspan in Mice
October 28, 2026
A recent study identified SRSF1, an RNA-processing and splicing factor, as a molecule with geroprotective potential. Inducing SRSF1 expression rejuvenated human cells in vitro, extended lifespan, and significantly reduced frailty in mice [1]. Alternative approaches Differentiated cells have the capacity to rejuvenate if an appropriate molecular
ARDD 2026: Traditional Biology to AI-Driven Breakthroughs
October 27, 2026
One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and might have contributed to this edition’s practical, entrepreneurial, and forward-oriented spirit. We have already reported on
The Regulatory Bottleneck in Aging Biology
October 26, 2026
Researchers are developing biomedical repair therapies to address multiple age-related diseases at once, yet they are forced to put them through regulatory pathways built for single-disease drugs. The result is delay, duplication, and unnecessary cost precisely when speed matters the most. The single-disease-indication trap Current regulation
Laura Minquini on the Quest for Female Longevity
October 23, 2026
Laura Minquini is not a scientist, but that hasn’t stopped her from joining the front lines of the war on aging: specifically, female reproductive aging. Several years ago, after a successful stint in consumer technology, Laura discovered the longevity field when decentralized science was all the
How Some Neuronal Cilia May Affect the Whole Body
October 22, 2026
A team of researchers has written a paper with a surprising finding: that many of the benefits of caloric restriction and increased NAD+ may be due to their effects on the cilia of hypothalamic neurons. Neuronal cilia have a relationship to overall health To interact with
AI Extracts Broader Health Insights From Routine CT Scans
October 20, 2026
A new study suggests that CT scans can provide information about a wide range of conditions, including some not typically diagnosed through imaging. Direct comparison with human radiologists is the next step [1]. Getting more from a scan A CT scan’s goal is usually to answer
An RNA Regulator Mitigates Senescence in Blood Vessels
October 19, 2026
Researchers publishing in Aging Cell have found that the regulatory protein MTR4 fights DNA damage in the blood vessel lining but decreases with aging. Vulnerable by nature This paper begins by noting the properties, and aging, of vascular endothelial cells (VECs), which line the blood vessels
Blocking STING Helps Preserve Bone in Aging Mice
October 16, 2026
A new study links STING-mediated signals from marrow fat cells to inflammation and declining NAD⁺ levels in bone-forming cells. Interrupting this pathway helped preserve aging bone [1]. Making old bones Our bones live a complex life, as they are constantly remodeled: cells called osteoclasts break down
Making SIRT1 and NAD+ Therapies Work in People
October 15, 2026
Reviewers publishing in Biology have elucidated SIRT1 functional reserve as an aspect of aging, describing how its depletion is an upstream cause of age-related disorders at the cellular level and explaining why many prospective therapies that increase SIRT1 and NAD+ have not had promising results. Managing
Menopausal Serum Protein Changes May Predict Brain Health
October 14, 2026
A recent analysis of serum protein changes identified 16 proteins related to inflammatory, synaptic, metabolic, and Alzheimer’s disease processes whose levels change during the menopausal transition [1]. These changes were linked to cognitive health later in life. The time for interventions Menopause is mostly known as
Low-Fat Vegan Diet Shows Benefits in Type 2 Diabetes
October 13, 2026
A human trial found that even without caloric restriction, a low-fat, plant-based diet improved blood sugar control, reduced liver fat, and lowered the quantity of advanced glycation end products (AGEs) in the skin [1]. An all-you-can-eat vegan buffet Type 2 diabetes is an age-related metabolic disorder
An Anti-Senescence Gene May Fight Spinal Disc Deterioration
October 12, 2026
In Aging Cell, a team of researchers has described how a little-known gene, ZNF865, has a significant influence on back pain through the regulation of cellular senescence. Lower back pain and senescence are related The link between cellular senescence and back pain has been thoroughly documented,
Gut Bacteria Molecule Slows Atherosclerosis in Mice
October 9, 2026
A new study highlights a fatty acid produced by a particular genus of bacteria as a “natural statin,” suggesting a new way of treating atherosclerosis [1]. Bacteria and cholesterol Atherosclerosis develops when cholesterol-rich particles accumulate in arterial walls, driving inflammation and plaque buildup. The liver helps
Untangling Differences in Senescent Cellular Signaling
October 8, 2026
In Aging, researchers have described the differences between the secretions of cells driven senescent through a cancer gene and cells that stopped proliferating due to p16 expression. A difference of kind The SASP is a mix of many components that have various effects on the cells