Category: News
Declining Autophagy Impairs Senescent Cell Clearance
October 6, 2026
A new study links an age-related decline in cellular maintenance to impaired immune clearance. Activating the pathway reduced signs of senescence in aged mice [1]. Senescence and autophagy Cellular senescence,
The Biomarkers That Predict Mortality Risk
October 5, 2026
Researchers have discovered key biomarkers that are strongly linked to all-cause mortality and identified four measurements with independent predictive power. Biological versus chronological This paper opens with a discussion of
FDA Leaders Name Longevity a Priority at ARDD
October 2, 2026
At a panel in Boston, senior officials announced plans to include aging in the agency’s regulatory science agenda and discussed how therapies could move toward approval. Longevity has a partner
Rejuvenation Roundup September 2026
October 1, 2026
Which generation will be considered “the last to die” of age-related diseases is ultimately a question of technological development and deployment. Here’s what’s been done on that front in September.
Transplanted Hearts Shift Toward Recipients’ Molecular Age
September 29, 2026
A new preprint study suggests that transplanted hearts’ epigenetic age and possibly function are influenced by their recipients’ age. The findings can be relevant to both expanding the donor pool
A New Metric for Overall Senescent Cell Burden
September 28, 2026
Researchers have created a deep learning-based biomarker, SASP Score, that evaluates the combined effects of the senescence-associated secretory phenotype (SASP) circulating in the bloodstream. Measuring an overall burden Gathering the
Creatine Protects Lean Mass Even Without Exercise
September 25, 2026
According to a new study, creatine supplementation might help maintain and increase lean mass even without diet or exercise. It also enhanced the effects of a combined diet and exercise
Giving Cells Fresh Mitochondria Helps Clear Damaged Ones
September 24, 2026
Researchers have discovered that BNIP3, which regulates mitochondrial maintenance, is increased with aging, harming the heart’s ability to process energy. Mitochondrial transplantation was found to be effective against this increase
Physical Activity Delays Ovarian Aging in Mice
September 23, 2026
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in
Transplanted Immune Cells Donate Mitochondria to Neighbors
September 22, 2026
According to a new study using a mouse model of a rare disease, transplanted immune cells donate their mitochondria to neighboring donor cells, improving energy production and rescuing function [1].
Intermittent Fasting Shows Promise in a Huntington’s Trial
September 21, 2026
In a pilot study, patients engaging in intermittent fasting demonstrated improvements in Huntington’s disease, a neurodegenerative condition currently considered untreatable. However, the study’s size and limitations call for more research
Thymus Grafts Grow in Mouse Spleens, Restoring Immunity
September 18, 2026
In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1]. Growing one organ inside another
Clearing Damaged Mitochondria to Fight Skin Photoaging
September 17, 2026
Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by
An Entirely New Target for Fighting Senescence
September 15, 2026
Researchers have established how a protein that is nearly absent in the literature, PTCHD4, is linked to cellular senescence. Very little previous work In most papers, after a customary discussion
Mitochondrial Performance May Strongly Influence Learning
September 14, 2026
A team of researchers has discovered that mitochondrial health and location may be critical to why cognitive plasticity decreases with age. Old mammals and new tricks The adage ‘you can’t
Declining Autophagy Impairs Senescent Cell Clearance
October 6, 2026
A new study links an age-related decline in cellular maintenance to impaired immune clearance. Activating the pathway reduced signs of senescence in aged mice [1]. Senescence and autophagy Cellular senescence, which occurs when cells stop dividing and start emitting largely pro-inflammatory stress signals, the senescence-associated secretory
The Biomarkers That Predict Mortality Risk
October 5, 2026
Researchers have discovered key biomarkers that are strongly linked to all-cause mortality and identified four measurements with independent predictive power. Biological versus chronological This paper opens with a discussion of a familiar fact for people interested in living longer: one’s biological age is not the same
FDA Leaders Name Longevity a Priority at ARDD
October 2, 2026
At a panel in Boston, senior officials announced plans to include aging in the agency’s regulatory science agenda and discussed how therapies could move toward approval. Longevity has a partner The 2026 edition of the Aging Research and Drug Discovery Meeting (ARDD) kicked off yesterday. This
Rejuvenation Roundup September 2026
October 1, 2026
Which generation will be considered “the last to die” of age-related diseases is ultimately a question of technological development and deployment. Here’s what’s been done on that front in September. Interviews The Last Generation to Die: Interview With Tim Maupin: Filmmaker Tim Maupin has spent a
Transplanted Hearts Shift Toward Recipients’ Molecular Age
September 29, 2026
A new preprint study suggests that transplanted hearts’ epigenetic age and possibly function are influenced by their recipients’ age. The findings can be relevant to both expanding the donor pool and rejuvenation through organ replacement [1]. The heart of the matter Over the last few decades,
A New Metric for Overall Senescent Cell Burden
September 28, 2026
Researchers have created a deep learning-based biomarker, SASP Score, that evaluates the combined effects of the senescence-associated secretory phenotype (SASP) circulating in the bloodstream. Measuring an overall burden Gathering the data needed to evaluate a person’s circulating SASP is as simple as taking a blood draw.
Creatine Protects Lean Mass Even Without Exercise
September 25, 2026
According to a new study, creatine supplementation might help maintain and increase lean mass even without diet or exercise. It also enhanced the effects of a combined diet and exercise intervention [1]. How to lose weight but not muscle As people age, they often accumulate fat
Giving Cells Fresh Mitochondria Helps Clear Damaged Ones
September 24, 2026
Researchers have discovered that BNIP3, which regulates mitochondrial maintenance, is increased with aging, harming the heart’s ability to process energy. Mitochondrial transplantation was found to be effective against this increase in a mouse model. The heart needs energy Mitophagy, the process of eliminating damaged mitochondria, is
Physical Activity Delays Ovarian Aging in Mice
September 23, 2026
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in mice. [1] Beyond reproduction The female reproductive system strongly influences the female aging trajectory, and its
Transplanted Immune Cells Donate Mitochondria to Neighbors
September 22, 2026
According to a new study using a mouse model of a rare disease, transplanted immune cells donate their mitochondria to neighboring donor cells, improving energy production and rescuing function [1]. Here, have some mitochondria Friedreich’s ataxia is a rare genetic disease in which deficiency in the
Intermittent Fasting Shows Promise in a Huntington’s Trial
September 21, 2026
In a pilot study, patients engaging in intermittent fasting demonstrated improvements in Huntington’s disease, a neurodegenerative condition currently considered untreatable. However, the study’s size and limitations call for more research [1]. Fast to survive Huntington’s disease is an inherited, progressive neurodegenerative disorder caused by an expansion
Thymus Grafts Grow in Mouse Spleens, Restoring Immunity
September 18, 2026
In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1]. Growing one organ inside another The thymus is a small but crucial organ, where T cells mature to become the backbone
Clearing Damaged Mitochondria to Fight Skin Photoaging
September 17, 2026
Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by restoring their cells’ ability to get rid of their own damaged mitochondria (mitophagy). Wrinkles are only
An Entirely New Target for Fighting Senescence
September 15, 2026
Researchers have established how a protein that is nearly absent in the literature, PTCHD4, is linked to cellular senescence. Very little previous work In most papers, after a customary discussion of the mechanics of cellular senescence and current methods of handling it and its repercussions, the
Mitochondrial Performance May Strongly Influence Learning
September 14, 2026
A team of researchers has discovered that mitochondrial health and location may be critical to why cognitive plasticity decreases with age. Old mammals and new tricks The adage ‘you can’t teach an old dog new tricks’ is true across a wide variety of organisms; neural plasticity