Category: News
Junyue Cao on How the Body Ages, Cell by Cell
May 8, 2026
Dr. Junyue Cao is a professor at the Rockefeller University, and his lab develops ultra-high-throughput single-cell technologies and applies them to the biology of aging. In a recent paper published
How Intestinal Aging Encourages Harmful Bacteria
May 7, 2026
In Aging Cell, researchers have elucidated the relationship between intestinal aging and age-related changes to the gut microbiome. Two interdependent biologies The human gut works through the interaction of two
Creatine Shows Synergy With Exercise in Older Adults
May 5, 2026
In a new study, the popular supplement creatine seemed to add to some of the beneficial effects of power training [1]. Trying the combination in older people Exercise might be
“Thinking” AI Outperforms Human Doctors on Real-Life Data
May 4, 2026
A new study has pit an advanced large language model against human physicians in tasks involving complex reasoning, treatment recommendations, and messy real-world patient records [1]. Testing a “thinking” model
The Longevity Investor Network Looks Back at 2025
May 1, 2026
The Longevity Investor Network (LIN) was created to help bridge the gap between promising longevity startups and the investors capable of helping them scale. Through curated monthly pitch sessions, educational
Rejuvenation Roundup April 2026
May 1, 2026
Aging is a multifaceted topic, and it’s becoming more and more clear that the only way to deal with it is piece by piece. Here’s what pieces our industry has
Some Researchers Choose Replacement Over Repair in Aging
April 30, 2026
A perspective published in Aging Cell details the replacement-based approaches being investigated by several research organizations. Repair versus replacement This perspective begins by noting the inherent difficulty of rejuvenating the
Daytime Napping and Mortality Association in Older Adults
April 29, 2026
A recent study found an association between longer and more frequent daytime napping and higher mortality risk. The authors suggest using napping frequency and duration as behavioral markers of increased
A Popular Senolytic Treatment Causes Brain Damage in Mice
April 28, 2026
A new study calls for caution in using the well-known senolytic treatment of dasatinib and quercetin (D+Q), showing that it causes damage in certain regions of the brain, similar to
Obesity’s Effects on the Immune System May Linger for Years
April 28, 2026
A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of obesity. In mice, the effect lasts for
A Robust Senescence Response Helps Wounds Heal
April 27, 2026
A team of scientists has examined how younger and older mice heal from wounds and found that more robust senescent cell activation in younger animals helps them heal faster. A
Reprogrammed Cardiomyocytes Soften the Blow in Heart Attack
April 24, 2026
A new study has found that partial reprogramming mitigates the damage of myocardial infarction in mice by helping heart muscle cells to complete division [1]. When heart cells get stuck
It’s Springtime and the Rejuvenation Field Is Flourishing
April 23, 2026
For those of us in the Northern Hemisphere, spring is here. This is a time of renewal and hope for better times ahead, echoing what our field is trying to
The Immune System Ages Differently in Men and Women
April 22, 2026
An investigation into the aging immune system identified age-related changes, including sex-dependent differences, in immune cell subpopulations and gene expression. In general, females showed greater age-related changes than males, including
Rapamycin Might Blunt Exercise Response in Humans
April 21, 2026
According to a new study, rapamycin probably interferes with exercise, blunting its effects in older human subjects. This result, however, might be specific to the particular protocol. Can they work
Junyue Cao on How the Body Ages, Cell by Cell
May 8, 2026
Dr. Junyue Cao is a professor at the Rockefeller University, and his lab develops ultra-high-throughput single-cell technologies and applies them to the biology of aging. In a recent paper published in Science, his team used a technique called EasySci-ATAC to profile chromatin accessibility in about seven
How Intestinal Aging Encourages Harmful Bacteria
May 7, 2026
In Aging Cell, researchers have elucidated the relationship between intestinal aging and age-related changes to the gut microbiome. Two interdependent biologies The human gut works through the interaction of two entirely different sets of cells. The first is the body’s actual cells, including the intestinal barrier
Creatine Shows Synergy With Exercise in Older Adults
May 5, 2026
In a new study, the popular supplement creatine seemed to add to some of the beneficial effects of power training [1]. Trying the combination in older people Exercise might be the most potent anti-aging intervention known to humans, but with age, building strength and muscle mass
“Thinking” AI Outperforms Human Doctors on Real-Life Data
May 4, 2026
A new study has pit an advanced large language model against human physicians in tasks involving complex reasoning, treatment recommendations, and messy real-world patient records [1]. Testing a “thinking” model The dream of a ‘computer doctor’ has existed since at least 1959 [2], but until the
The Longevity Investor Network Looks Back at 2025
May 1, 2026
The Longevity Investor Network (LIN) was created to help bridge the gap between promising longevity startups and the investors capable of helping them scale. Through curated monthly pitch sessions, educational seminars, collaborative diligence, and ecosystem-building events, LIN provides a structured platform for investors to discover, evaluate,
Rejuvenation Roundup April 2026
May 1, 2026
Aging is a multifaceted topic, and it’s becoming more and more clear that the only way to deal with it is piece by piece. Here’s what pieces our industry has put together in April. Advocacy and Analysis It’s Springtime and the Rejuvenation Field Is Flourishing: For
Some Researchers Choose Replacement Over Repair in Aging
April 30, 2026
A perspective published in Aging Cell details the replacement-based approaches being investigated by several research organizations. Repair versus replacement This perspective begins by noting the inherent difficulty of rejuvenating the human body because of the vast variety of interventions that need to be performed at multiple
Daytime Napping and Mortality Association in Older Adults
April 29, 2026
A recent study found an association between longer and more frequent daytime napping and higher mortality risk. The authors suggest using napping frequency and duration as behavioral markers of increased mortality risk [1]. Common activity with a dark side Daytime napping is a relatively common activity
A Popular Senolytic Treatment Causes Brain Damage in Mice
April 28, 2026
A new study calls for caution in using the well-known senolytic treatment of dasatinib and quercetin (D+Q), showing that it causes damage in certain regions of the brain, similar to what is observed in multiple sclerosis [1]. Stem cell senescence prevents brain repair Multiple sclerosis (MS)
Obesity’s Effects on the Immune System May Linger for Years
April 28, 2026
A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of obesity. In mice, the effect lasts for weeks, while its existence and duration in humans are to be determined [1]. The inflammation that
A Robust Senescence Response Helps Wounds Heal
April 27, 2026
A team of scientists has examined how younger and older mice heal from wounds and found that more robust senescent cell activation in younger animals helps them heal faster. A double-edged sword Multiple experiments have found that senescent cells and proper wound healing are intrinsically linked.
Reprogrammed Cardiomyocytes Soften the Blow in Heart Attack
April 24, 2026
A new study has found that partial reprogramming mitigates the damage of myocardial infarction in mice by helping heart muscle cells to complete division [1]. When heart cells get stuck When a heart attack (myocardial infarction, MI) kills a patch of heart muscle, the adult mammalian
It’s Springtime and the Rejuvenation Field Is Flourishing
April 23, 2026
For those of us in the Northern Hemisphere, spring is here. This is a time of renewal and hope for better times ahead, echoing what our field is trying to achieve: the rejuvenation of aging cells and tissues to keep older people free from age-related diseases.
The Immune System Ages Differently in Men and Women
April 22, 2026
An investigation into the aging immune system identified age-related changes, including sex-dependent differences, in immune cell subpopulations and gene expression. In general, females showed greater age-related changes than males, including greater changes in autoimmune gene expression [1]. Cell-by-cell analysis Aging results in changes to the function
Rapamycin Might Blunt Exercise Response in Humans
April 21, 2026
According to a new study, rapamycin probably interferes with exercise, blunting its effects in older human subjects. This result, however, might be specific to the particular protocol. Can they work together? Physical activity is one of the most potent pro-longevity interventions currently available [2]. Rapamycin is