Category: News
More Autophagy Reduces Toxin-Induced Kidney Failure in Mice
July 23, 2026
Autophagy, which increases in younger mice under toxic stress, does not increase in older mice and leaves them susceptible to acute kidney injury (AKI). Increasing autophagic flux by targeting a
The Progress and Future of Biological Aging Clocks
July 22, 2026
A recent review discusses the development of biological aging clocks, their capabilities and limitations, the discoveries they enabled, and possible future developments in this area [1]. How do we measure
Regular Training Erases Parts of Muscle Aging Signature
July 21, 2026
A new study suggests that regular planned exercise, not just being generally active, protects against certain aspects of muscle aging [1]. Are trained muscles younger? With age, skeletal muscles lose
Gabriel Cian on Building the 2060 Longevity Ecosystem
July 21, 2026
In this follow-up interview, we speak with Gabriel Cian about how the 2060 ecosystem has evolved since last year’s Forum, what he learned from the first edition, and how he
Exosomes From Stem Cells Fight Liver Disease in Mice
July 20, 2026
Researchers have described a method of using exosomes derived from mesenchymal stem cells (MSCs) to fight harmful metabolic changes in the liver. Another look at exosomes This is far from
Engineered Enzyme Reverses Age-Related Protein Damage
July 17, 2026
Scientists have engineered an enzyme that removes an advanced glycation end product (AGE) from proteins. This type of age-related modification, which affects protein function and can trigger inflammation, has previously
Activating a Key Receptor Fights Thymic Involution in Mice
July 16, 2026
Publishing in Aging Cell, researchers have devised a way to delay the aging of the thymus by targeting GPR40, a key receptor in its epithelial cells. The organ that involutes
Peripheral Inflammation May Drive Parkinson’s
July 14, 2026
A new study suggests that aging or Parkinson’s-triggering mutations create inflammation in peripheral tissues, and then circulating extracellular vesicles spread it to the brain, which might contribute to the disease
Combining Senolytics and Stem Cells Shows Promise in Mice
July 10, 2026
A new study associated with Immorta Bio suggests that combining a senolytic vaccine with mesenchymal stem cells might create a synergistic impact. However, the findings rest on acute, artificially induced
An Experimental Proposal for Blocking Ambient Radiation
July 9, 2026
A perspective published in Aging and Disease has recommended the use of underground laboratory space in order to remove the effects of surface radiation on biological clocks. A question of
Optimizing Guidelines Toward Optimal Health Outcomes
July 8, 2026
In a recently published perspective paper, the author argues that the UK’s official health guidelines on physical activity and protein intake should be revised to recommend levels necessary to achieve
Rescuing Calcium Ion Homeostasis Extends Mouse Lifespan
July 7, 2026
Scientists have linked disrupted Ca²⁺ homeostasis to aging in both progeroid and naturally aging mice. Rescuing it with a well-known antidepressant significantly increased the animals’ median and maximum lifespan [1].
How Muscle Loss and Bone Loss Are Related
July 6, 2026
Researchers have elucidated some of the links between the age-related loss of muscle (sarcopenia) and the age-related loss of bone (osteoporosis). Related in multiple ways Substantial previous research has described
Intermittent Fasting Increases Lifespan in Male Mice
July 3, 2026
Restricting food access to an 8-hour window increased median lifespan in male mice by 12%. However, that might be due to voluntary caloric restriction induced by the regimen [1]. You
Rejuvenation Roundup June 2026
July 1, 2026
Doing something about aging seems to require action at the most basic genomic level. Here’s what’s been done there and in other areas in June. Interviews The Thalion Initiative: A
More Autophagy Reduces Toxin-Induced Kidney Failure in Mice
July 23, 2026
Autophagy, which increases in younger mice under toxic stress, does not increase in older mice and leaves them susceptible to acute kidney injury (AKI). Increasing autophagic flux by targeting a key molecule, transcription factor EB (TFEB), alleviates some of this damage. An acute disease with lasting
The Progress and Future of Biological Aging Clocks
July 22, 2026
A recent review discusses the development of biological aging clocks, their capabilities and limitations, the discoveries they enabled, and possible future developments in this area [1]. How do we measure aging? Developments in science and technology have allowed researchers to move beyond speculation and philosophical debates
Regular Training Erases Parts of Muscle Aging Signature
July 21, 2026
A new study suggests that regular planned exercise, not just being generally active, protects against certain aspects of muscle aging [1]. Are trained muscles younger? With age, skeletal muscles lose strength, metabolic flexibility, and mitochondrial capacity. While regular exercise slows many aspects of functional aging [2],
Gabriel Cian on Building the 2060 Longevity Ecosystem
July 21, 2026
In this follow-up interview, we speak with Gabriel Cian about how the 2060 ecosystem has evolved since last year’s Forum, what he learned from the first edition, and how he is thinking about investment, scientific credibility, health optimization, policy, and the future of longevity in Europe.
Exosomes From Stem Cells Fight Liver Disease in Mice
July 20, 2026
Researchers have described a method of using exosomes derived from mesenchymal stem cells (MSCs) to fight harmful metabolic changes in the liver. Another look at exosomes This is far from the first attempt at using MSC-derived exosomes, particularly exosomes derived from MSCs originally taken from human
Engineered Enzyme Reverses Age-Related Protein Damage
July 17, 2026
Scientists have engineered an enzyme that removes an advanced glycation end product (AGE) from proteins. This type of age-related modification, which affects protein function and can trigger inflammation, has previously been considered extremely hard to reverse [1]. Can we rejuvenate proteins? Many proteins are continually broken
Activating a Key Receptor Fights Thymic Involution in Mice
July 16, 2026
Publishing in Aging Cell, researchers have devised a way to delay the aging of the thymus by targeting GPR40, a key receptor in its epithelial cells. The organ that involutes The thymus trains a certain subset of immune cells, which are named T cells due to
Peripheral Inflammation May Drive Parkinson’s
July 14, 2026
A new study suggests that aging or Parkinson’s-triggering mutations create inflammation in peripheral tissues, and then circulating extracellular vesicles spread it to the brain, which might contribute to the disease [1]. Brain on fire Nature made the brain remarkably well-protected, including from the elements by the
Combining Senolytics and Stem Cells Shows Promise in Mice
July 10, 2026
A new study associated with Immorta Bio suggests that combining a senolytic vaccine with mesenchymal stem cells might create a synergistic impact. However, the findings rest on acute, artificially induced injury models rather than natural aging [1]. Clearing out senescent cells to help stem cells work
An Experimental Proposal for Blocking Ambient Radiation
July 9, 2026
A perspective published in Aging and Disease has recommended the use of underground laboratory space in order to remove the effects of surface radiation on biological clocks. A question of entropy The cascading failure of bodily systems, leading to the loss of organ function, sits downstream
Optimizing Guidelines Toward Optimal Health Outcomes
July 8, 2026
In a recently published perspective paper, the author argues that the UK’s official health guidelines on physical activity and protein intake should be revised to recommend levels necessary to achieve optimal health, rather than the bare minimum currently recommended [1]. From bare minimum to optimizing for
Rescuing Calcium Ion Homeostasis Extends Mouse Lifespan
July 7, 2026
Scientists have linked disrupted Ca²⁺ homeostasis to aging in both progeroid and naturally aging mice. Rescuing it with a well-known antidepressant significantly increased the animals’ median and maximum lifespan [1]. Calcium ions in progeria and natural aging Cells use calcium ions (Ca²⁺) for signaling, and a
How Muscle Loss and Bone Loss Are Related
July 6, 2026
Researchers have elucidated some of the links between the age-related loss of muscle (sarcopenia) and the age-related loss of bone (osteoporosis). Related in multiple ways Substantial previous research has described the relationship between muscle and bone health. While misloading can be dangerous, ordinary mechanical loading, which
Intermittent Fasting Increases Lifespan in Male Mice
July 3, 2026
Restricting food access to an 8-hour window increased median lifespan in male mice by 12%. However, that might be due to voluntary caloric restriction induced by the regimen [1]. You are when you eat Time-restricted eating (TRE), also known as intermittent fasting, has become a popular
Rejuvenation Roundup June 2026
July 1, 2026
Doing something about aging seems to require action at the most basic genomic level. Here’s what’s been done there and in other areas in June. Interviews The Thalion Initiative: A New Non-Profit With Big Ambitions: The longevity field remains small and starved for resources, especially the