Category: News
Serotonin Signals Suppress Physical Activity in Aging Mice
November 13, 2026
A new study has found that increased production of serotonin by neurons in a particular brain region inhibits dopamine production and willingness to move, causing loss of activity. Killing serotonin-producing
A New Target for Fighting Tau Tangles in Neurons
November 12, 2026
Researchers have found that HDAC7 bridges together GSK3β and hyperphosphorylated tau protein (hTau) in neurons, which may spur Alzheimer’s disease. Getting rid of HDAC7 in hTau model mice ameliorated their
The Short Peptide Elamipretide Delays Ovarian Aging in Mice
November 11, 2026
A recent study showed that a treatment with the short peptide elamipretide reversed multiple signs of age-related decline in oocyte quality in mice and in human oocytes in vitro [1].
A Supplement Kills Senescent Cells and Extends Life in Mice
November 10, 2026
A new study shows healthspan and lifespan increases in male mice following late-life treatment with vanadyl sulfate, a food-derived molecule marketed as an over-the-counter supplement [1]. Searching for vulnerabilities In
Inflammaging and Poor Sleep Contribute to One Another
November 9, 2026
After a review of substantial literature, scientists publishing in Aging Cell have concluded that poor sleep quality and inflammaging worsen each other in a vicious cycle, reducing quality of life
Longevity Supplement Improved Blood Vessels in a Human Trial
November 6, 2026
In a clinical trial, the supplement NOVOS Core was associated with significant improvements in artery function and systolic blood pressure. It is unknown which particular ingredients are responsible for the
Momentum on Two Fronts for Rejuvenation
November 5, 2026
This month has been marked by progress in both the regulatory and investment sides of rejuvenation biotechnology. For years, the field has faced two major challenges: scientific advances outpacing the
Why Male Mice Lose Anti-Cancer Immunity Earlier
November 3, 2026
A new study found that shrinking reserves of naive T cells weaken tumor recognition in male mice by middle age more than in females. Restoring thymic activity improved protection [1].
Rejuvenation Roundup October 2026
November 2, 2026
As the weather cools down, the race for functional interventions heats up, and members of our field have been looking for ways to push through bottlenecks both regulatory and scientific.
An Anti-Senescence Vaccine Increases Mouse Lifespan
October 30, 2026
In a new study, late-life treatment with a three-element senolytic vaccine led to lower senescence markers and a 12% increase in median lifespan in female B6 mice. However, short-lived controls
An Astrocytic Factor Slows Whole-Body Aging in Mice
October 29, 2026
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice. A factor from a well-known family FGFs are
Rejuvenation Factor Extends Lifespan and Healthspan in Mice
October 28, 2026
A recent study identified SRSF1, an RNA-processing and splicing factor, as a molecule with geroprotective potential. Inducing SRSF1 expression rejuvenated human cells in vitro, extended lifespan, and significantly reduced frailty
ARDD 2026: Traditional Biology to AI-Driven Breakthroughs
October 27, 2026
One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and
The Regulatory Bottleneck in Aging Biology
October 26, 2026
Researchers are developing biomedical repair therapies to address multiple age-related diseases at once, yet they are forced to put them through regulatory pathways built for single-disease drugs. The result is
Laura Minquini on the Quest for Female Longevity
October 23, 2026
Laura Minquini is not a scientist, but that hasn’t stopped her from joining the front lines of the war on aging: specifically, female reproductive aging. Several years ago, after a
Serotonin Signals Suppress Physical Activity in Aging Mice
November 13, 2026
A new study has found that increased production of serotonin by neurons in a particular brain region inhibits dopamine production and willingness to move, causing loss of activity. Killing serotonin-producing neurons reversed the effect [1]. Can’t or won’t? Physical activity tends to decline with age. As
A New Target for Fighting Tau Tangles in Neurons
November 12, 2026
Researchers have found that HDAC7 bridges together GSK3β and hyperphosphorylated tau protein (hTau) in neurons, which may spur Alzheimer’s disease. Getting rid of HDAC7 in hTau model mice ameliorated their cognitive decline. How proteins go wrong While tau protein is necessary for proper neural function, it
The Short Peptide Elamipretide Delays Ovarian Aging in Mice
November 11, 2026
A recent study showed that a treatment with the short peptide elamipretide reversed multiple signs of age-related decline in oocyte quality in mice and in human oocytes in vitro [1]. An early decline In females, the reproductive system ages relatively early in life, with fertility declining
A Supplement Kills Senescent Cells and Extends Life in Mice
November 10, 2026
A new study shows healthspan and lifespan increases in male mice following late-life treatment with vanadyl sulfate, a food-derived molecule marketed as an over-the-counter supplement [1]. Searching for vulnerabilities In a new study published in Nature Aging, a group of researchers from the University of Chicago
Inflammaging and Poor Sleep Contribute to One Another
November 9, 2026
After a review of substantial literature, scientists publishing in Aging Cell have concluded that poor sleep quality and inflammaging worsen each other in a vicious cycle, reducing quality of life and fueling other age-related diseases. More than a peripheral link This review begins with a brief
Longevity Supplement Improved Blood Vessels in a Human Trial
November 6, 2026
In a clinical trial, the supplement NOVOS Core was associated with significant improvements in artery function and systolic blood pressure. It is unknown which particular ingredients are responsible for the effect [1]. To the Core of the matter Led by Christian Heiss, Professor of Cardiovascular Medicine,
Momentum on Two Fronts for Rejuvenation
November 5, 2026
This month has been marked by progress in both the regulatory and investment sides of rejuvenation biotechnology. For years, the field has faced two major challenges: scientific advances outpacing the regulatory systems meant to evaluate them, and a capital environment that has often struggled to distinguish
Why Male Mice Lose Anti-Cancer Immunity Earlier
November 3, 2026
A new study found that shrinking reserves of naive T cells weaken tumor recognition in male mice by middle age more than in females. Restoring thymic activity improved protection [1]. Do men lose anti-cancer defenses with age? CD8+ T cells are immune cells that can kill
Rejuvenation Roundup October 2026
November 2, 2026
As the weather cools down, the race for functional interventions heats up, and members of our field have been looking for ways to push through bottlenecks both regulatory and scientific. Here’s what we’ve reported last month. Interviews Laura Minquini on the Quest for Female Longevity: Laura
An Anti-Senescence Vaccine Increases Mouse Lifespan
October 30, 2026
In a new study, late-life treatment with a three-element senolytic vaccine led to lower senescence markers and a 12% increase in median lifespan in female B6 mice. However, short-lived controls complicate the picture [1]. Helping the immune system kill “zombie cells” Cellular senescence is a double-edged
An Astrocytic Factor Slows Whole-Body Aging in Mice
October 29, 2026
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice. A factor from a well-known family FGFs are signaling molecules that share structural and functional commonalities and play crucial roles in biology, including neural
Rejuvenation Factor Extends Lifespan and Healthspan in Mice
October 28, 2026
A recent study identified SRSF1, an RNA-processing and splicing factor, as a molecule with geroprotective potential. Inducing SRSF1 expression rejuvenated human cells in vitro, extended lifespan, and significantly reduced frailty in mice [1]. Alternative approaches Differentiated cells have the capacity to rejuvenate if an appropriate molecular
ARDD 2026: Traditional Biology to AI-Driven Breakthroughs
October 27, 2026
One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and might have contributed to this edition’s practical, entrepreneurial, and forward-oriented spirit. We have already reported on
The Regulatory Bottleneck in Aging Biology
October 26, 2026
Researchers are developing biomedical repair therapies to address multiple age-related diseases at once, yet they are forced to put them through regulatory pathways built for single-disease drugs. The result is delay, duplication, and unnecessary cost precisely when speed matters the most. The single-disease-indication trap Current regulation
Laura Minquini on the Quest for Female Longevity
October 23, 2026
Laura Minquini is not a scientist, but that hasn’t stopped her from joining the front lines of the war on aging: specifically, female reproductive aging. Several years ago, after a successful stint in consumer technology, Laura discovered the longevity field when decentralized science was all the