Category: News
People With Positive Outlooks Have Better Aging Outcomes
March 11, 2026
A recent study published in Geriatrics debunks the assumption that an older chronological age results in an inevitable and universal decline in health. The researchers reported that a significant number
Scientists Successfully Freeze and Rewarm Mouse Brain Slices
March 10, 2026
In a new study, researchers have vitrified mouse brain slices and then a complete brain with encouraging results: upon rewarming, much of the neuronal function was preserved [1]. The bumpy
A Review of How the Heart Ages
March 9, 2026
The European Heart Journal has published a review of what happens to the human heart as it ages, noting the cellular effects of mitochondrial dysfunction and cellular senescence along with
Fat Composition Affects T Cell-Mediated Immunity
March 6, 2026
Scientists have found that the ratio between poly- and monounsaturated fatty acids affects the viability of T cells as well as both humoral and anti-tumor immunity [1]. The iron death
How Inflammaging Makes Pneumonia Worse in Mice
March 5, 2026
Researchers publishing in Aging Cell have discovered how older organisms’ susceptibility to pneumonia is related to inflammatory factors. Short-lived infection fighters Polymorphonuclear leukocytes, more commonly known as neutrophils, are part
Resistance Exercise Training Slows Down Brain Aging
March 4, 2026
Using brain clock models that analyzed MRI images of the brains of elderly people who underwent one year of resistance training, researchers concluded that both heavy and moderate resistance training
Novel Mechanism for Parkinson’s Is Linked to ATP Deficiency
March 3, 2026
Scientists have discovered that ATP deficiency disrupts dopamine processing in synapses, leading to the accumulation of the harmful protein species that characterize Parkinson’s disease. ATP supplementation helps, but the road
Rejuvenation Roundup February 2026
March 2, 2026
Plenty of crucial work has been done in the rejuvenation world over the past four weeks, and last month, we’ve spoken to several researchers about the progress being made. Interviews
Cellular Reprogramming: The Expert Roundup
February 27, 2026
Cellular reprogramming is one of the technologies most associated with longevity. The field was created in 2006, when Shinya Yamanaka showed that a cocktail of four transcription factors, commonly known
A Metabolic Shift Fuels Stem Cell Dysfunction
February 26, 2026
Researchers publishing in the Nature journal Cell Discovery have described how the age-related attenuation of a key metabolic axis causes human adipose-derived stem cells (hASCs) to lose functional capabilities. Pinpointing
João Pedro de Magalhães on the Ethics of Longevity
February 25, 2026
João Pedro de Magalhães, professor at the University of Birmingham, is known as a prominent geroscientist who has been in the field forever, enriching it with top-tier research. He is
Menopausal Hormone Therapy Does Not Increase Mortality
February 25, 2026
An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality [1]. A controversial therapy One of the first major changes that women undergo as
Thermogeneration by White Fat Could Be Used to Treat Obesity
February 24, 2026
Scientists have discovered that, like brown fat, white fat has a mechanism that burns fuel to produce heat. This effect could potentially be used to create weight loss drugs [1].
How a Sirtuin Protects Against Brain Diseases
February 23, 2026
In Aging Cell, researchers have explained how the sirtuin SIRT6 protects against proteostasis-related brain disorders by maintaining the function of nucleoli and limiting protein production. The nucleus and nucleoli A
AI Tool Sets New Standard in Diagnosing Rare Diseases
February 20, 2026
A new system, which consists of a large LLM and a network of agentic tools, outperformed several other models and human physicians [1]. Too rare to easily diagnose Rare diseases
People With Positive Outlooks Have Better Aging Outcomes
March 11, 2026
A recent study published in Geriatrics debunks the assumption that an older chronological age results in an inevitable and universal decline in health. The researchers reported that a significant number of older adults who participated in the study experienced an improvement in cognitive and/or physical functioning
Scientists Successfully Freeze and Rewarm Mouse Brain Slices
March 10, 2026
In a new study, researchers have vitrified mouse brain slices and then a complete brain with encouraging results: upon rewarming, much of the neuronal function was preserved [1]. The bumpy road to cryopreservation Successful cryopreservation is a coveted prize in medicine, as cryopreserving organs and tissues
A Review of How the Heart Ages
March 9, 2026
The European Heart Journal has published a review of what happens to the human heart as it ages, noting the cellular effects of mitochondrial dysfunction and cellular senescence along with more visible changes such as hypertrophy and fibrosis. A constantly working organ The reviewers begin this
Fat Composition Affects T Cell-Mediated Immunity
March 6, 2026
Scientists have found that the ratio between poly- and monounsaturated fatty acids affects the viability of T cells as well as both humoral and anti-tumor immunity [1]. The iron death Some fats are broadly recognized as healthy while others are considered unhealthy, but the reality might
How Inflammaging Makes Pneumonia Worse in Mice
March 5, 2026
Researchers publishing in Aging Cell have discovered how older organisms’ susceptibility to pneumonia is related to inflammatory factors. Short-lived infection fighters Polymorphonuclear leukocytes, more commonly known as neutrophils, are part of the first line of defense against lung infections. Illnesses cause these immune cells to be
Resistance Exercise Training Slows Down Brain Aging
March 4, 2026
Using brain clock models that analyzed MRI images of the brains of elderly people who underwent one year of resistance training, researchers concluded that both heavy and moderate resistance training slow brain aging [1]. The broad benefits Exercise has been linked to many benefits, such as
Novel Mechanism for Parkinson’s Is Linked to ATP Deficiency
March 3, 2026
Scientists have discovered that ATP deficiency disrupts dopamine processing in synapses, leading to the accumulation of the harmful protein species that characterize Parkinson’s disease. ATP supplementation helps, but the road to the clinic might be long [1]. Parkinson’s and dopamine Parkinson’s disease is defined by two
Rejuvenation Roundup February 2026
March 2, 2026
Plenty of crucial work has been done in the rejuvenation world over the past four weeks, and last month, we’ve spoken to several researchers about the progress being made. Interviews João Pedro de Magalhães on the Ethics of Longevity: João Pedro de Magalhães, professor at the
Cellular Reprogramming: The Expert Roundup
February 27, 2026
Cellular reprogramming is one of the technologies most associated with longevity. The field was created in 2006, when Shinya Yamanaka showed that a cocktail of four transcription factors, commonly known as OSKM, can cause de-differentiation and massive rejuvenation of a cell, creating an iPSC (induced pluripotent
A Metabolic Shift Fuels Stem Cell Dysfunction
February 26, 2026
Researchers publishing in the Nature journal Cell Discovery have described how the age-related attenuation of a key metabolic axis causes human adipose-derived stem cells (hASCs) to lose functional capabilities. Pinpointing the loss of function This paper begins by highlighting a core problem of using self-derived (autologous)
João Pedro de Magalhães on the Ethics of Longevity
February 25, 2026
João Pedro de Magalhães, professor at the University of Birmingham, is known as a prominent geroscientist who has been in the field forever, enriching it with top-tier research. He is also a skilled longevity advocate who has long taken interest in the ethics of longevity, first
Menopausal Hormone Therapy Does Not Increase Mortality
February 25, 2026
An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality [1]. A controversial therapy One of the first major changes that women undergo as they age is menopause, which usually occurs between 45 and 55 years of age. Menopause not
Thermogeneration by White Fat Could Be Used to Treat Obesity
February 24, 2026
Scientists have discovered that, like brown fat, white fat has a mechanism that burns fuel to produce heat. This effect could potentially be used to create weight loss drugs [1]. Central heating Cells use energy to power various cellular processes, with heat being a byproduct. However,
How a Sirtuin Protects Against Brain Diseases
February 23, 2026
In Aging Cell, researchers have explained how the sirtuin SIRT6 protects against proteostasis-related brain disorders by maintaining the function of nucleoli and limiting protein production. The nucleus and nucleoli A cell’s nucleus has one or more nucleoli, where the cell does its critical work of synthesizing
AI Tool Sets New Standard in Diagnosing Rare Diseases
February 20, 2026
A new system, which consists of a large LLM and a network of agentic tools, outperformed several other models and human physicians [1]. Too rare to easily diagnose Rare diseases can be notoriously hard to diagnose. Patients average over 5 years to receive a correct diagnosis,