Creating a Future Where Everyone Can Live Longer, Healthier Lives

Building A Global Ecosystem To Advance Research That Will Overcome Age-Related Disease And Extend Healthy Human Lifespan

End Of Year Giving 2025

Help Us Power Another Year of Impact

Join us for another year of driving the science and systems that support longer, healthier lives for all.
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Our Mission

We Are Building a Future Free of Age-Related Disease

Lifespan  Research Institute is focused on strategically driving forward science to extend healthy human lifespan through advocacy, ecosystem building, and direct support of cutting edge research into the root causes of aging.

Age-related diseases such as Alzheimer’s, heart disease, and cancer,  cause untold harm, both in terms of personal suffering and socio-economic effects. Like treating the trunk of a tree as opposed to its various branches, it is a much more effective strategy to treat age-related maladies by addressing the process that is at the heart of them all, the aging process itself.

Our Four Pillars

Our Research

We conduct targeted scientific research with the explicit goal of accelerating the development of therapies that address the root causes of aging.

Education Opportunities​

Our educational programs offer several options for students interested in engaging with our mission of preventing age-related diseases.

Longevity Investor Network

Through our investor network, we catalyze private investment in biotechnology companies developing interventions that target the root mechanisms of aging.

Public Advocacy​

We make the ground fertile for the entire field through advocacy initiatives that foster societal change, increasing available public and private funding for aging research.

Addressing the Root Causes of Aging is a Much Better Way to Fight Disease

Healthy Life Expectancy and Total Life Expectancy Gained

Cure Cancer

Cure Heart Disease

Improve Biological Aging

Research Highlights & Outreach

Study Description

Advancing scientific understanding and community engagement in aging and longevity.

Research

New Paper from LRI’s Sharma Lab on Senescent Cell Targeting

Study Description

This study identifies an aberrant localization of the protein LAMP1 on the surface of senescent cells. Cells that presented LAMP1 on the surface showed clear signs of having a senescent/aged phenotype. The team was able to target LAMP1 on the surface of senescent cells to eliminate them.

Volunteers

LRI Needs Volunteers for Aging and Longevity Study.

Study Description

Lifespan Research Institute is seeking volunteers for blood donations. Your participation will help advance our understanding of the immune system and mitochondrial biology in aging.

outreach

Keith Comito Moderates Panel on the Geopolitics of Aging Research at the A4LI DC Summit

Study Description

At the A4LI DC Summit Event, Keith Comito moderated the panel “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

outreach

Keith Comito Moderates Panel on the Geopolitics of Aging Research at the A4LI DC Summit

Study Description

At the A4LI DC Summit Event, Keith Comito moderated the panel “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

Latest LRI News

Lifespan Alliance

Lifespan Alliance Launch & New Leadership at LRI

Mountain View, California — Lifespan Research Institute, a nonprofit leader in longevity science and advocacy, announces the launch of the Lifespan Alliance, a sponsorship initiative uniting mission-driven companies and visionary

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