As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do not divide or support the tissues of which they are part; instead, they emit a range of potentially harmful chemical signals that encourage nearby cells to enter the same senescent state. Their presence causes many problems: they degrade tissue function, increase levels of chronic inflammation, and can even eventually raise the risk of cancer and other age-related diseases. A new class of drugs known as senolytics focuses on the destruction of these stubborn “death-resistant” cells from the body in order to reduce inflammation and improve tissue function. New research proposes to remove some of these senescent cells in order to promote healthy longevity.