March 21, 2025
In a new study, researchers report producing self-assembling nanotubes and rings made from RNA molecules inside artificial cell-like lipid vesicles. In the future, this technology could facilitate the creation of synthetic cells for various research, diagnostic, and therapeutic applications [1]. Paperless origami DNA and RNA molecules are central to life, carrying essential genetic information for...
February 03, 2025
In the Journal of Nanobiotechnology, researchers have described a new method of delivering a long-lasting treatment into cartilage. A protein that promotes autophagy Previous work has linked expression of the FGF18 protein with healthy cartilage and joints [1]. Problems with the gene responsible for FGF18 lead to osteoarthritis [2], and it has been found to...
January 09, 2025
In a journal called Small, researchers have described a new targeting mechanism for delivering senolytic compounds where they need to go. Finding the right nanoparticle Why We Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they...
September 03, 2024
In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer. It is rarely diagnosed early and very aggressive. It also responds poorly to treatment, primarily because...
May 17, 2024
Scientists have demonstrated that viral particles from a harmless plant virus can be used as an adjuvant therapy to prevent recurrence of disease and metastasis formation in several cancer models [1]. The challenge of keeping cancer at bay Medicine’s progress in treating cancer has been patchy: impressive with some cancers, dead-slow with others. For instance,...
January 08, 2024
Researchers have described how specialized nanoparticles, which deliver rapamycin and the antioxidant astaxanthin, restore macrophage balance and reduce inflammation in a mouse model of osteoarthritis. A matter of polarization Inflammation is a critical part of arthritis. Previous studies have found that inflammation of the membranes in joints (synovitis) strongly contributes to osteoarthritis [1]; in fact,...