Tag: Naked Mole Rats

Scientists have found that the cGAS protein in naked mole rats, a famously long-lived species, boosts DNA repair, while the human version tends to hamper it. The difference boils down to just four amino acids [1]. DNA repair and cGAS Despite their unassuming appearance, naked mole rats (NMRs) are stars in the longevity field. These...

The researchers of a previous controversial paper on the naked mole-rat's impressive longevity have returned, publishing data in GeroScience that bolsters their original findings. A darling of longevity The naked mole-rat, an unusually long-lived rodent species that lives in large colonies, has long been a mystery of gerontology, and investigations into its biology have yielded...

Publishing in Nature, a team of researchers including Vadim Gladyshev, Steve Horvath, and Vera Gorbunova has investigated the role of hyaluronan, which naked mole rats have in abundance, as a protective mechanism in a mouse model. An established mechanism Naked mole rats are notably resistant to cancer, and these researchers have previously determined that this...

The Journal Club for August returns live to the Lifespan.io Facebook channel on September 5th at 12:00 Eastern hosted by Dr. Oliver Medvedik. This time we are taking a look at a paper where researchers have transfered a lifespan and healthspan boosting mechanism from the naked mole rat, a very long lived rodent, to mice....

To understand human longevity, we need to put it into perspective. Are we relatively long-lived or short-lived creatures? After all, among all the plants and animals in nature, we find a vast variety of lifespans, from several hours to several millennia, and possibly even more. While humans are the most long-lived primates, our lifespan pales...

Naked mole rats are long-lived rodents famous for their resistance to cancer and sustained healthy lifespan. In a new study published in the Journal of Investigative Dermatology, researchers have shown that the skin of older members of this species is characterized by high expression of longevity-associated and tumor-suppressing genes [1]. Getting under the skin  Skin...