August 17, 2023
Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct measurements Unlike other association studies that are used to evaluate biomarkers of aging, this study did not use data from a pre-existing biobank or related...
July 09, 2023
Researchers have explained in Nature Aging how klotho, a factor associated with longevity, improves the cognitive abilities of rhesus macaques. Moving on from mice This paper begins with a discussion of klotho and how it relates to aging. In mice, klotho has been found to improve cognitive function [1], even though systemic administration does not...
April 12, 2023
Research published in Heliyon has outlined the effects of F-Klb, a signaling molecule receptor that is released under metabolic stress, on the hearts of diabetic patients. Check out Cardio Diagnostics to learn more about their test kits. A protector that loses its effectiveness Fibroblast growth factor 21 (FGF21) is a regulator of metabolism that is...
November 02, 2022
In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition of minerals in the cardiovascular system, is a complex pathological process that accompanies aging. It is associated with an increased risk of stroke, coronary artery...
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. KidneyThe kidney's main function is to filter waste products out of the blood and deliver the resulting urine to the bladder. The functional unit of the kidney is called the nephron, and each kidney...
October 20, 2021
A recent study in The Journals of Gerontology, Series A has associated low klotho levels with mortality in Americans over the age of 40. Klotho and aging What is Klotho?Klotho, named after the Greek mythological figure, is an enzyme that can be either circulating or bound to cell membranes. It is expressed most highly in...