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Tag: Klotho

Heart diagnostics
Research published in Heliyon has outlined the effects of F-Klb, a signaling molecule receptor that is released under metabolic stress, on the hearts of diabetic patients. Check out Cardio Diagnostics to learn more about their test kits. A protector that loses its effectiveness Fibroblast growth factor 21 (FGF21) is a regulator of metabolism that is...
Clogged pipes
In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. β€˜Rusty’ arteries Vascular calcification, the deposition of minerals in the cardiovascular system, is a complex pathological process that accompanies aging. It is associated with an increased risk of stroke, coronary artery...
Olives
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. KidneyThe kidney's main function is to filter waste products out of the blood and deliver the resulting urine to the bladder. The functional unit of the kidney is called the nephron, and each kidney...
Three Fates
A recent study in The Journals of Gerontology, Series A has associated low klotho levels with mortality in Americans over the age of 40. Klotho and aging What is Klotho?Klotho, named after the Greek mythological figure, is an enzyme that can be either circulating or bound to cell membranes. It is expressed most highly in...
Arthritic joint pain
Researchers have successfully reversed the course of osteoarthritis in rats by combining two molecules, one of which, a-Klotho, has long been a popular subject of anti-aging research. A classic age-related disease Osteoarthritis (OA) is a classic example of a wear-and-tear disease. Its manifestations are in the slow degeneration of articular cartilage, the appearance of bone...
Fat mouse
A team of researchers, including renowned geneticist Professor George Church, has published a new paper demonstrating the mitigation of multiple age-related diseases using a multi-target gene therapy. Treating multiple age-related diseases at once George Church is a very prominent figure in genetics and aging research, and he created quite a stir last year when he...