Tag: Fibroblasts

Scientists have discovered that cancer cells recruit fibroblasts to support tumor growth by transferring mitochondria into them. Blocking this process might be a new way to fight the deadly disease [1]. It goes both ways Cancer doesn’t act alone. Its success often hinges on recruiting neighboring cells into cooperation with cancer cells. Sometimes, those neighboring...

In Aging Cell, a team of researchers has described how the health of skin fibroblasts relates to physical and functional ability. Frailty, capacity, and skin cells This paper begins with an explanation of how frailty and capacity are defined. The World Health Organization defines it as an overall state of reduced strength, endurance, and physiogical...

In Aging Cell, researchers have described the specific cell types that give exercise protective effects against motor nerve degeneration. A different level of back problems With aging, the prevalence of nerves connecting to muscle tissue dwindles, a phenomenon known as denervation [1]. This has been linked to a depopulation of the alpha motor neurons in...

In Aging, researchers have described a subpopulation of fibroblasts that nurture ovarian cancer tumors and shield them from harm. Cancer's natural defenders Ovarian cancer is particularly dangerous, both in death rates and in recurrence [1]. Normally, chemicals that contain platinum are effective, but this sort of cancer develops resistance to such treatments; after that, prognoses...

In Aging, researchers have described how the changing production of skin cells' proteins is a core part of their age-related decline. Understanding why skin cells lose their function In healthy skin, dermal fibroblasts produce the proteins needed to maintain the extracellular matrix (ECM), the network of collagen and elastin that holds soft tissues together [1]....

Scientists from Duke University have found a way to make adult fibroblasts differentiate into cardiomyocytes, which might help develop better heart attack treatments [1]. The imperfect repair Myocardial infarction, or heart attack, is a leading cause of death and disability. It happens when the blood flow to a part of the heart gets blocked, often...