December 15, 2025
In Aging, researchers have described how they removed visceral fat from older male mice by targeting the metabolic regulatory protein CD47. A key regulator of metabolism Visible fat carried around the body is subcutaneous fat. While this kind of fat is obviously not healthy to have in large amounts, it is not as immediately dangerous...
May 14, 2024
A new study suggests that aerobic medium-to-vigorous physical activity benefits obese and diabetic people the most when conducted in the evening hours [1]. Do you really need morning runs? Physical activity is an essential part of the longevity-conscious lifestyle and one of the best life-extending interventions currently available. However, questions remain as to what types...
April 25, 2024
Researchers have published the results of a study in Aging Cell, finding some evidence that type 2 diabetes causes accelerated aging. Later-generation clocks only What Are Epigenetic ClocksAn epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different kinds...
March 04, 2024
A new publication in iScience has described a novel way in which heart tissue can be encouraged to accept a gene therapy by using ultrasound to create cavitation bubbles. A little-known target and a new delivery vector This paper begins with a discussion of S-adenosylhomocysteine (SAH), a compound that, in excess, is associated with an...
October 31, 2023
A new study suggests that while it is possible to be both obese and healthy, this phenotype considerably increases the risk of getting diabetes, mainly because it is hard to maintain [1]. Chubby and happy? Obesity is a known comorbidity in numerous chronic conditions, including age-related ones. It has been shown to positively correlate with...
July 25, 2023
A new systematic review lends support to the idea that statins, which are life-saving cholesterol-lowering drugs, are associated with an increased risk of insulin resistance and type 2 diabetes [1]. Statins’ dark side Statins, drugs that improve the lipid profile by reducing harmful LDL cholesterol, are considered one of the biggest successes in medicine in...