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Tag: Cognitive Decline

Synaptic Transmission
Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer's disease, still defy current treatment options, impeding attempts to increase human lifespan. According to the theory of competing risks, we cannot hope to meaningfully increase lifespan until all...
Elderly brain
A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from living people To begin their study, the researchers examined a middle-aged to old (MATO) cohort ranging in age from 52 to 89. This cohort consists...
Brain Blood Vessels
After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable drugs in the world. Yet, sildenafil's hailed effect on erectile dysfunction was discovered serendipitously. Originally, sildenafil was studied as a candidate drug for heart-related chest...
Cognitive puzzle
Scientists have confirmed yet another positive effect of metformin: its prolonged use by people with diabetes lowers the risk of cognitive impairment and cerebral small vessel disease [1]. A meta-drug? Metformin is one of the top candidate geroprotective (life-prolonging) drugs for several reasons. First, it has been shown to extend lifespan and healthspan in animal...
Jean Hebert at EARD2021
At Ending Age-Related Diseases 2021, Elena Milova interviewed Dr. Jean Hébert on how the human brain can be restored to youthful function. Script Elena: Greetings to the participants of Ending Age-Related Diseases 2021. This conference brings together thought leaders and researchers working on rejuvenation biotechnology with the goal of extending healthy human life. The supposed...
Meditation
A team of researchers, including Dr. Olga M Limecki of TU Dresden University, has published a review on the effect of mindfulness meditation and loving-kindness compassion meditation (LKCM) and proposed a model to study it [1]. Mindfulness and compassion mediation defined One of our Science to Save the World episodes discusses what meditation does to...