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Tag: Cognitive Decline

Neurons
Cognitive decline and neurological aging may involve a peptide known as adropin, according to new research. The identification of this link offers a new perspective on the aging brain and points to novel potential therapies. A newly discovered metabolic neuropeptide The adropin protein is encoded by the Energy Homeostasis Associated (ENHO) gene, and as the...
Stressful stimuli
Researchers publishing in Aging have found that stresses, both biological and in daily life, harm one of our fundamental abilities to correctly process what's going on around us. What is sensory gating? Sensory gating is the brain's ability to filter out irrelevant stimuli after the first time it experiences them. It reflects our ability to...
Older people playing chess
New research in humans published in PLoS ONE shows society-wide improvements in cognition for older adults, but it also highlights a need to specifically target age-related cognitive decline. Humans have gotten much smarter over time Cognition is a broad term used to refer to many different types of intelligence. The loss of cognitive ability is...
Lab mouse
Molecular Psychiatry has recently published a report from the University of Cambridge detailing how the brain’s extracellular matrix (ECM) changes with age, negatively impacting memory, and how modifying the components of the brain ECM can revitalize memory in mice [1]. What is neuroplasticity? Neuroplasticity is the ability of neurons to form new connections. This ability...
Mice playing
A study published in Nature Communications has shown that an environment rich in stimuli changes the epigenetics of the mouse hippocampus, making the brains of aged mice more like those of young mice [1]. What is an enriched environment? For mice, enriched environments (ENRs) are "large cages equipped with frequently rearranged toys, providing physical, cognitive,...
Rat in maze
Researchers from Hebei Medical University in China have found that testosterone supplementation ameliorates age-related brain dysfunction in male rats. A focus on mitochondria Why we Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that harm cells and cause increasing levels of...