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Tag: Cognitive Decline

Elderly bicycling
A new study suggests that greater diversity of everyday activities is associated with a slower rate of age-related cognitive decline, independently of the amount of physical activity [1]. Variety or quantity? It is widely accepted that being cognitively and socially active can slow down age-associated cognitive decline. Scientists also generally agree that the range of...
Curcumin
Scientists have found that EGCG and curcumin, two well-known antioxidants, are effective both alone and especially in combination in a mouse model of cognitive decline induced by oxidative stress [1]. Not the usual stress Oxidative stress results mostly from molecules called reactive oxygen species (ROS), which are byproducts of normal chemical reactions in the body....
Rhesus macaques
Researchers have explained in Nature Aging how klotho, a factor associated with longevity, improves the cognitive abilities of rhesus macaques. Moving on from mice This paper begins with a discussion of klotho and how it relates to aging. In mice, klotho has been found to improve cognitive function [1], even though systemic administration does not...
Brain clock
Researchers publishing in Aging have found a correlation between cognitive decline and measurements of epigenetic aging. Familiar epigenetic clocks Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different kinds of clocks, and...
Elderly Japanese couple
Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory bacterium The researchers begin their paper by noting that mild cognitive impairment (MCI) is associated with memory loss and is frequent precursor of Alzheimer's disease...
Multivitamins
In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one study Multivitamins are among the most popular dietary supplements, but their effectiveness is often questioned. While some studies did fail to find any significant benefits...