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Reason .

Reason .

About Reason .

Long-time advocate for rejuvenation biotechnology and director of the aging research website Fight Aging. Reason is also the founder of Repair Biotechnologies,  a new venture that will focus on the development of gene therapies relevant to human rejuvenation. Their initial focus is on the development of gene therapies to regenerate the thymus, which has the potential to restore production of T cells in older individuals, or may help patients suffering from immunodeficiency.

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Articles from this author

Fight Aging!
April 15, 2021
Yuva Biosciences is attempting to treat skin aging by improving mitochondrial function, and they are taking a cosmeceutical approach. It is far faster and less costly to bring treatments to market via the cosmetics regulatory pathway than via the Investigational New Drug pathway. One has to accept considerable restrictions over what sort of approaches can...
Fight Aging!
April 15, 2021
The decline of the immune system is of great importance in aging. Vulnerability to infection, a decreased surveillance of senescent cells and cancerous cells, and growing chronic inflammation all take their toll. A sizable fraction of this problem stems from the diminished supply of new T cells of the adaptive immune system. T cells begin...
Nicotinamide Riboside Supplementation Beginning in Mid-Life Slows Osteoporosis in Mice
April 14, 2021
In today's open access paper, researchers report that long-term supplementation with nicotinamide riboside in mice, starting from mid-life and continuing into old age, slows the pace of osteoporosis. The extracellular matrix of bone tissue is constantly remodeled over time, broken down by osteoclasts and built up by osteoblasts. Osteoporosis is caused by a growing imbalance...
Nicotinamide Riboside Supplementation Beginning in Mid-Life Slows Osteoporosis in Mice
April 14, 2021
In today's open access paper, researchers report that long-term supplementation with nicotinamide riboside in mice, starting from mid-life and continuing into old age, slows the pace of osteoporosis. The extracellular matrix of bone tissue is constantly remodeled over time, broken down by osteoclasts and built up by osteoblasts. Osteoporosis is caused by a growing imbalance...
Fight Aging!
April 14, 2021
In the past few years Jim Mellon, high net worth investor and philanthropist, has put in a great deal of time and effort to help push forward the development of a biotech industry focused on intervention in human aging. He has donated to non-profits in the aging research space, set up aging-focused conference series, founded...
In Horses, the Gut Microbiome Interacts with Mitochondria to Improve Function
April 14, 2021
The study here is carried out in horses, but it is reasonable to expect to find very similar mechanisms in other mammals. The beneficial populations of the gut microbiome provide metabolites that steer cell function and exist in symbiosis with the host animal. Mitochondria, the power plants of the cell, are the evolved descendants of...