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Oliver Medvedik, Ph.D.

About Oliver Medvedik, Ph.D.

Oliver Medvedik, Co-founder of Genspace citizen science laboratory in Brooklyn NY, earned his Ph.D. at Harvard Medical School in the Biomedical and Biological Sciences program. As part of his doctoral work he has used single-celled budding yeast as a model system to map the genetic pathways that underlie the processes of aging in more complex organisms, such as humans. Prior to arriving in Boston for his doctoral studies, he has lived most of his life in New York City. He obtained his bachelor’s degree in biology from Hunter College, City University of New York. Since graduating from Harvard, he has worked as a biotechnology consultant, taught molecular biology to numerous undergraduates at Harvard University and mentored two of Harvard’s teams for the international genetically engineered machines competition (IGEM) held annually at M.I.T. Oliver is also the Director of The Maurice Kanbar Center for Biomedical Engineering at the Cooper Union, New York City. The Maurice Kanbar Center for Biomedical Engineering is open to all Cooper Union faculty and students working on bioengineering projects requiring equipment and space for tissue culture, genetic engineering, biomechanics, and related research. Faculty that is currently using the facility are pursuing groundbreaking biomedical research in such fields as biomedical devices, tissue engineering, obstructive sleep apnea biomechanics also collaborating with several major New York City-based hospitals. The Kanbar Center continues to provide space for undergraduate teams participating in the international genetically engineered competition (iGEM) during the summer, as well as space for courses that offer a biological laboratory component.
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The topic for the September edition of the Journal Club was the recent human trial of the senolytic agents dasatinib and quercetin. For the researchers at the Mayo Clinic, this was a follow-on study from their previous human trial targeting IPF. This time the researchers ran a study to see how senolytics influenced diabetic kidney...
The Journal Club on August 27 was hosted by Dr. Oliver Medvedik and special guest Dr. Alexander Tyshkovskiy, who works at the Gladyshev at Brigham and Women’s Hospital, Harvard Medical School, Boston. The topic was the recent paper "Identification and Application of Gene Expression Signatures Associated with Lifespan Extension" published in Cell Metabolism. This study...
For the June edition of Journal Club, Dr. Oliver Medvedik and guests took a look at the recent human trial of urolithin A, a metabolite produced by microflora and an active ingredient in pomegranates that is linked to increased levels of mitophagy in aged animals. Urolithin A is a byproduct created when bacteria in the...
The February Journal Club focused on the recent paper "Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances". Hosted by Dr. Oliver Medvedik, we were joined by study author Dr. Peter Joshi from the University of Edinburgh, UK, who guides us through this fascinating genomics study of human...
Tau protein aggregation is associated with cellular senescence in the brain was the topic for the November Journal Club. This is an important paper as it shows how senescent cells contribute to Alzheimer’s disease and how removing them appears to improve the condition. Dr. Oliver Medvedik, Steve Hill, and Victor Bjoerk discussed this interesting study...
For the August Journal Club, we took a look at a new paper that shows inhibiting TGFβ can boost liver regeneration [1]. We also discussed another related paper from 2015 by Conboy et al. which showed regeneration in aged mice was possible if TGFβ was inhibited [2]. Taken together, the two papers both confirm that systemic...