Matthew O'Connor

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Trouble sleeping
After a review of substantial literature, scientists publishing in Aging Cell have concluded that poor sleep quality and inflammaging worsen each other in a vicious cycle, reducing quality of life and fueling other age-related diseases. More than a peripheral link Chronic InflammationChronic inflammation refers to a persistent, low-grade buzz of immune activity that settles into...
NOVOS logo
In a clinical trial, the supplement NOVOS Core was associated with significant improvements in artery function and systolic blood pressure. It is unknown which particular ingredients are responsible for the effect [1]. To the Core of the matter Led by Christian Heiss, Professor of Cardiovascular Medicine, researchers at the University of Surrey put NOVOS Core,...
Editorial 16-9
This month has been marked by progress in both the regulatory and investment sides of rejuvenation biotechnology. For years, the field has faced two major challenges: scientific advances outpacing the regulatory systems meant to evaluate them, and a capital environment that has often struggled to distinguish serious translational work from noise and hype. Fortunately, recent...
Thymus and tumor
A new study found that shrinking reserves of naive T cells weaken tumor recognition in male mice by middle age more than in females. Restoring thymic activity improved protection [1]. Do men lose anti-cancer defenses with age? CD8+ T cells are immune cells that can kill infected or cancerous cells. However, an individual T cell...
Rejuvenation Roundup October 2026
As the weather cools down, the race for functional interventions heats up, and members of our field have been looking for ways to push through bottlenecks both regulatory and scientific. Here's what we've reported last month. Interviews Laura Minquini on the Quest for Female Longevity: Laura Minquini is not a scientist, but that hasn’t stopped...
College for T Cells
In a new study, late-life treatment with a three-element senolytic vaccine led to lower senescence markers and a 12% increase in median lifespan in female B6 mice. However, short-lived controls complicate the picture [1]. Helping the immune system kill “zombie cells” Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do...