Matthew O'Connor

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Repeated lifting
Researchers have discovered that the osteoarthritis-inducing effects of excessive mechanical stress can be mitigated by increasing miR-330, a key regulator in cartilage and bone cells. Backbreaking labor is exactly that It has been long-held conventional wisdom that a lifetime of heavy physical labor leads to the early development of arthritis. This has been backed up...
Forever Healthy Foundation
The Forever Healthy Foundation today publicly launched evipedia.ai, an open online encyclopedia of in-depth evidence reviews covering more than 500 health and longevity interventions, including first-generation rejuvenation therapies, supplements, botanicals, lifestyle protocols, and more. Evipedia was built to solve a problem familiar to anyone navigating the longevity field: the literature is vast, fragmented, fast-moving, and...
Todd White Interview
The longevity field remains small and starved for resources, especially the subfield devoted to the fundamental biology of aging, despite near-universal agreement that solving aging requires understanding it first. With VCs looking for clinical successes and state funding drying up for many projects, some enthusiasts are turning to a nonprofit model. That path is anything...
Rejuvenation Roundup May 2026
Approaches that modify the processes of aging at their roots have gone well beyond basic research and into therapies intended for the clinic within the next few years. Here's how the field has advanced in May. Team and activities The Longevity Investor Network Looks Back at 2025: Through curated monthly pitch sessions, educational seminars, collaborative...
Pathway forward
The report, titled “Pathways to Longevity”, introduces several important longevity concepts to the general reader and is another sign that the field is coming of age and entering the mainstream. People do want to live longer From time to time, Harvard Health Publishing issues Special Health Reports – consumer-facing, doctor-reviewed guides translating medical research for...
DNA modeling
In a preprint published in arXiv, researchers from Altos Labs have described a machine learning algorithm that performs end-to-end prediction of how cells' gene expression will respond to interventions. The need for prediction Simulating biological processes on a computer is an incredibly difficult task. While advanced algorithms such as Google's AlphaFold have revolutionized protein folding,...