Donate
Login
Donate

Matthew O'Connor

Related Organizations

Logo
Director

Campaign List

Articles from this author

Drug combination

A Combination NAD+ Treatment Has Benefits for Mice

Researchers have found that simultaneously supplying NAD+ through NMN and reducing its loss through apigenin restores muscle function and bone structure to aged mice. A well-documented issue NAD+ is one of the most well-documented compounds in biology, including within the context of aging. Precursor supplementation has been repeatedly documented to have measurable benefits; for example,...
Human eye

Life Bio’s Trial: Is the FDA Warming to Rejuvenation?

The FDA views aging as an inevitability, not a medical target. However, with Life Biosciences moving the first cellular reprogramming therapy into human trials this year, things might be changing there. If this technique works in resetting the biological age of the human eye, the entire multibillion-dollar longevity industry could move to the center of...
Time-restricted eating

The Timing of Meals Matters for Biological Aging

A recent study investigated a connection between the timing of meals and the rate of biological aging. These findings suggest that later timing of the first and last meals is associated with faster aging [1]. Finding the right patterns and rhythms Chrono-nutrition is an approach that connects eating patterns, circadian rhythms, and health outcomes [2]....
Excited neurons

APOE4 Increases Neurons’ Excitability Before Symptoms Appear

The pro-Alzheimer's allele APOE4 makes hippocampal neurons in mice smaller and hyperexcitable. This effect, which resembles epilepsy and accelerated aging, can be mitigated by manipulating a neuronal protein [1]. Before symptoms arise Alzheimer's disease begins long before symptoms appear, building silently for decades. The single strongest genetic risk factor for the common, late-onset form of...
Waking up after surgery

A Target for Ameliorating Post-Operative Delirium

Researchers have discovered a potential treatment for post-operative delirium, which accelerates cognitive decline in older people. A common problem with long-term effects Roughly a quarter of older people suffer from delirium after surgery [1], which rises to around half if the surgery is particularly invasive or high-risk [2]. This increases the length of hospital stays...
Insilico Medicine

Insilico and Eli Lilly Announce a Major Collaboration

Building on two previous deals between the companies, this new agreement is potentially worth up to $2.75 billion and involves Lilly licensing assets from Insilico’s pipeline. More than software Earlier this week, the AI-driven drug discovery company Insilico Medicine announced a large-scale collaboration with the pharmaceutical giant Eli Lilly. The deal is worth up to...
Load More