Lifespan Research Institute

Matthew O'Connor

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Older man thinking
A recent study suggests that cognitive enrichment throughout life is associated with reduced dementia risk, and it has the potential to delay the onset of dementia and mild cognitive impairment by five to seven years [1]. Cognitive stimulation Engagement in cognitively stimulating activities has been linked to lower dementia incidence, better cognitive function, and a...
NUS Healthy Longevity Conference
The NUS Academy for Healthy Longevity invites you to the Geromedicine Conference, set to take place from February 26-27, 2026, at the National University of Singapore. This premier event will gather global experts in geroscience, researchers, clinicians and industry leaders to explore the translation of geroscience into real-world interventions aimed at optimizing health and extending...
Healthy foods
Scientists have pitted five diets against each other to see which one is associated with more years of life gained [1]. The clash of the diets Unhealthy eating is recognized as a globally leading cause of death [2]. Surprisingly, few studies have actually evaluated the gains in life expectancy associated with adherence to a healthy...
Mouse in maze
Researchers have found that altering a growth hormone receptor in the brain adipose tissue of aged male mice slows their mental aging and allows them to perform far better on cognitive tests. Growth signaling is not necessarily good The axis of growth hormone and insulin-like growth factor 1 (IGF-1) is well-known in aging, and the...
Longevity Innovation Forum 2026
San Diego, CA – March 11–12, 2026 - Longevity Global will host the inaugural Longevity Innovation Forum, a two-day gathering bringing together leading scientists, clinicians, biotech founders, investors, and longevity enthusiasts advancing the science and translation of healthy aging. Held in San Diego’s thriving biotech hub, the Forum will spotlight Southern California’s growing longevity ecosystem...
Mouse in maze
Scientists have applied partial reprogramming to memory-encoding neurons (engrams) and achieved memory improvements in Alzheimer’s models and wild-type mice [1]. Rejuvenating neurons Partial cellular reprogramming, which uses certain factors to rejuvenate cells while maintaining their identity) has shown promise across various conditions and cell types, including neurons [2]. Rejuvenating these long-lived brain cells is imperative...