Matthew O'Connor

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FDA at ARDD
At a panel in Boston, senior officials announced plans to include aging in the agency’s regulatory science agenda and discussed how therapies could move toward approval. Longevity has a partner The 2026 edition of the Aging Research and Drug Discovery Meeting (ARDD) kicked off yesterday. This is one of the biggest and longest-running longevity conferences,...
Biomarkers of Aging Consortium
The Biomarkers of Aging Consortium will host its fourth annual Biomarkers of Aging Conference on October 5 and 6, 2026, at the Joseph B. Martin Conference Center at Harvard Medical School. The meeting brings together academic, clinical, industry, regulatory, and philanthropic leaders working to develop, validate, and apply biomarkers of aging. Therapies that target aging...
Rejuvenation Roundup September 2026
Which generation will be considered "the last to die" of age-related diseases is ultimately a question of technological development and deployment. Here's what's been done on that front in September. Interviews The Last Generation to Die: Interview With Tim Maupin: Filmmaker Tim Maupin has spent a number of years developing The Last Generation to Die,...
Heart Acclimatization
A new preprint study suggests that transplanted hearts’ epigenetic age and possibly function are influenced by their recipients’ age. The findings can be relevant to both expanding the donor pool and rejuvenation through organ replacement [1]. The heart of the matter Over the last few decades, organ transplantation has revolutionized treatment of multiple conditions. It...
Bad blood vessel proteins
Researchers have created a deep learning-based biomarker, SASP Score, that evaluates the combined effects of the senescence-associated secretory phenotype (SASP) circulating in the bloodstream. Measuring an overall burden Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they...
Strength
According to a new study, creatine supplementation might help maintain and increase lean mass even without diet or exercise. It also enhanced the effects of a combined diet and exercise intervention [1]. How to lose weight but not muscle As people age, they often accumulate fat while losing muscle. When these changes occur together, in...