Matthew O'Connor

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Forever Healthy Foundation
Staying informed about health and longevity interventions can be tedious and time-consuming. Often it involves manually decoding a supplement label with numerous compounds, reading a blog post about some therapy, or an X-post that name-drops a peptide — and having to look up every item manually. The Evipedia browser extension takes this challenge head-on. It...
Thymus in body
A recent study identified the thymus hormone thymulin as a molecule with the potential to reduce inflammation in an age-dependent manner. Treating cancer-bearing mice with this molecule made other cancer treatments more effective [1]. The aging immune system Aging has a profound impact on the immune system. It leads to a progressive decline in immune...
A new study proposes a theoretical framework that explains why the more complex an animal is, the harder it is to move the needle on its rate of aging [1]. A problem of great complexity A familiar puzzle in geroscience is that while many of the same longevity-related pathways are highly evolutionarily conserved, manipulating them...
Crowded blood cells
Researchers have discovered why the protein AGGF1 has significant effects on blood pressure and published their findings in Aging Cell. Blood pressure is a condition of its own The authors begin their paper by discussing high blood pressure (hypertension), one of the most commonly known medical issues and a significant contributor to both disability and...
Wei-Wu He
Human Longevity Inc., a company founded in 2013 by a trio of visionaries – Craig Venter, Peter Diamandis, and Robert Hariri – initially inspired high hopes. Several years and several hundred million dollars later, however, the company entered what many people saw as a period of turmoil. Dr. Wei-Wu He, an early investor in HLI,...
Pasta
A team of researchers has developed Pasta, a transcriptomic clock that accurately predicts the age-related effects of various compounds and gene expressions. Epigenetics versus transcriptomics What Are Epigenetic ClocksAn epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different...