Matthew O'Connor

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Gut bacteria
In Aging Cell, researchers have elucidated the relationship between intestinal aging and age-related changes to the gut microbiome. Two interdependent biologies The human gut works through the interaction of two entirely different sets of cells. The first is the body's actual cells, including the intestinal barrier between the gut and the rest of the body,...
Creatine powder
In a new study, the popular supplement creatine seemed to add to some of the beneficial effects of power training [1]. Trying the combination in older people Exercise might be the most potent anti-aging intervention known to humans, but with age, building strength and muscle mass becomes harder. Also, not all types of exercise are...
Robot doctor
A new study has pit an advanced large language model against human physicians in tasks involving complex reasoning, treatment recommendations, and messy real-world patient records [1]. Testing a “thinking” model The dream of a ‘computer doctor’ has existed since at least 1959 [2], but until the recent rise of large language models, no computer program...
LIN Report
The Longevity Investor Network (LIN) was created to help bridge the gap between promising longevity startups and the investors capable of helping them scale. Through curated monthly pitch sessions, educational seminars, collaborative diligence, and ecosystem-building events, LIN provides a structured platform for investors to discover, evaluate, and support companies working at the forefront of aging...
Rejuvenation Roundup April 2026
Aging is a multifaceted topic, and it's becoming more and more clear that the only way to deal with it is piece by piece. Here's what pieces our industry has put together in April. Advocacy and Analysis It's Springtime and the Rejuvenation Field Is Flourishing: For those of us in the Northern Hemisphere, spring is...
New part and old part
A perspective published in Aging Cell details the replacement-based approaches being investigated by several research organizations. Repair versus replacement This perspective begins by noting the inherent difficulty of rejuvenating the human body because of the vast variety of interventions that need to be performed at multiple levels, from the molecular to the whole-body. It defines...