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Tag: Quercetin

Broken bone
A study published in the Journal of Clinical Investigation has reported that senescent cells are largely responsible for slow bone healing in aged animals and that senolytics, which remove these harmful cells, can speed bone regeneration. A brief outline of bone healing BoneBone tissue serves as the primary structural component of our bodies. It protects...
Weightlifting Mouse
A paper published in GeroScience has reported that older mice taking the well-known senolytic combination of dasatinib and quercetin (D+Q) are able to build muscle more like young mice. Senescent cells harm muscle development Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support...
Diabetes Heart
The latest research published in Diabetes has implicated senescent cardiac stem cells as the link between diabetes and cardiovascular disease [1]. Why does diabetes increase the risk of cardiovascular disease? Type 2 diabetes mellitus is closely related to aging. Aging is a major risk factor for diabetes, and individuals with diabetes exhibit several characteristics of...
Rat bones
A new study in ACS Applied Materials and Interfaces used a combined geroscience and tissue engineering approach to regenerate bone in aged rats [1]. Replacement or rejuvenation? Too often, tissue engineering and longevity therapeutics are viewed as competing strategies – two different paths to potentially combat aging. In tissue engineering, cells and biomaterials are used...
Vaccination
The journal Nature has published a letter communication regarding a senolytic vaccination study [1]. These letters are typically research studies that the editor chooses to urgently publish due to the importance they hold for the other researchers in the field. They may or may not be peer reviewed before this publication. Background Why we Age:...
Old and Young Mice
A new publication in Aging Cell has found divergent results between the post-injury muscle regeneration of young and old mice treated with senolytics [1]. Senescent cells: Friend or foe for muscle regeneration? Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...