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Tag: Obesity

Weight Loss
A large Phase 3 study published in the New England Journal of Medicine shows that an existing drug combined with a healthy diet and mild exercise leads to an average weight loss of 20% [1]. Diet and exercise are not always enough Being a known comorbid factor in many diseases of aging, obesity is tightly...
In a new review paper, scientists show that exercise can alleviate age-related cognitive decline, but not all types of exercise are created equal [1]. Watch your head Lifestyle choices, such as exercise and diet, are the most powerful anti-aging interventions currently available to us, and they might be the only effective ones. Exercise, in particular,...
Thoughtful old man
A team of Spanish researchers has examined how glucose imbalance leads to neurological disorders through the failure of adipocytokines. What are adipocytokines? These compounds' name seems a bit concerning: "adipo-" refers to fat, and a cytokine is a cellular signal most commonly known for being part of the deadly cytokine storm associated with severe immunological...
Many foods contain selenium such as nuts, eggs, mushrooms, and some meats.
A recent study has shown that mice given selenium supplements were protected against the effects of a high-fat diet, similar to mice with a restricted methonine intake. Methonine restriction and caloric restriction It is well known among the longevity community that restricting calories leads to health benefits, and the practice of caloric restriction (CR) is...
Fat mouse
Researchers have discovered a chemical pathway that alleviates many harmful consequences of obesity while having little effect on obesity itself [1]. Obesity is bad for your lifespan. This is one of the fundamental truths of longevity science. Obesity drastically increases our susceptibility to cardiovascular diseases, type 2 diabetes, cancer, and other morbidities. It promotes inflammaging,...
A picture of brown fat cells
A group of researchers has used CRISPR to create energy-dissipating brown adipocytes (fat cells) from white preadipocytes. The new cells were then shown to alleviate obesity in mice [1]. Obesity: the nemesis of longevity Obesity is one of humanity’s deadliest enemies. It is a known comorbidity in a plethora of diseases, including age-related, such as...