Tag: Obesity

A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver disease [1]. These diseases, representing fundamental problems with how the human body uses energy, are heavily linked to systemic...

In a new study published in Endocrinology and Metabolism, researchers have shown that fat rather than sugar is the macronutrient that drives obesity and other detrimental metabolic changes if it constitutes a large proportion of dietary calories [1]. Obesity, diet, and the microbiome Obesity is associated with a dysregulation of several molecular pathways, which lead...

In a new paper, Ryan K. Masters, professor at CU Boulder, suggests that when adjusted for body shape and lifelong shifts, the relationship between BMI and mortality is more linear and robust than previously thought, with normal BMI being the healthiest [1]. BMI's many problems Most existing research shows a U-shaped relationship between body-mass index...

Scientists have shown that long-term treatment with a popular NAD+ precursor can raise NAD+ levels in blood and muscle and increase mitochondria content and function [1]. Twin-based design NAD+ is an important coenzyme that performs multiple functions, including mitochondrial energy production. NAD+ levels decrease with aging, which has been shown to underlie other age-related diseases....

Research published in Immunity & Ageing has shown that obesity has significant, aging-associated effects on behavior and immunity in the brains of mice. Known effects on humans and mice The researchers introduce this study by discussing human studies. It is well known that obesity is a risk factor for severe metabolic disorders, such as diabetes...

Pitching two variants of the Mediterranean diet against each other in a randomized controlled trial, scientists have found that the plant-oriented one, which contained more polyphenols, was more effective for weight loss [1]. Beyond the Med diet A healthy diet is one of the most powerful anti-aging interventions available today, but the question of which...