February 03, 2023
Scientists have shown that a popular senolytic combination of dasatinib and quercetin improves glucose tolerance and fasting blood glucose levels in aged mice [1]. The question of metabolism Cellular senescence is one of the hallmarks of aging, and senolytics, drugs that clear away senescent cells, have been shown to ameliorate some aging phenotypes. However, not...
October 21, 2022
Scientists have shown that both high-intensity interval training (HIIT) and time-restricted eating improve metabolism in healthy overweight women, with their combination providing the biggest effect [1]. Which one is better? Good dietary habits and physical activity are currently our best options for living longer and healthier lives. In recent years, two interventions have been gaining...
August 02, 2022
Researchers publishing in Journal of Biomedical Science have concluded that hesperetin, a compound found in various herbs, improves longevity in mice by promoting the expression of the pro-longevity gene Cisd2. Mitochondria and Cisd2 This paper begins with an explanation of mitochondrial dysfunction, one of the hallmarks of aging, and the function of Cisd2. Previous research...
February 22, 2022
In a study published in Nature Aging, a group of scientists has shown that NAD+ levels are correlated not only with age but with physical activity, with elder athletes rivaling normal young adults [1]. NAD: small, crucial, age-related Nicotinamide adenine dinucleotide (NAD) is as important as it is tiny. As its name suggests, this molecule...
November 10, 2021
New mouse data published in the latest issue of Aging Cell highlights the aging benefits of a novel NF-κB-based drug. NF-κB in aging and disease NF-κB is a transcription factor found in nearly all animal cell types. It is activated in response to multiple physiological insults, such as stress, reactive oxygen species (ROS), and viral...
October 05, 2021
Researchers have proven that our bodies partially compensate for calories burned during exercise by cutting energy expenditure on vital functions. Their discovery might explain why it can be so hard to lose weight by working out [1]. The three components of energy expenditure As much as we love covering mind-blowing scientific breakthroughs in the longevity...
