November 12, 2024
At the University of Wisconsin-Madison, Dr. Rozalyn Anderson is studying one of the oldest-known and yet most powerful anti-aging interventions: caloric restriction (CR). Back in 1935, CR helped launch the entire longevity field when a pioneering study by Clive McCay and his colleagues at Cornell University demonstrated that CR without malnutrition significantly extends the lifespan...
November 06, 2024
In a new study, the researchers administered human umbilical cord-derived mesenchymal stem cells (HUCMSCs) to aged mice and observed reduced degeneration in multiple organs, changes to microbial composition, metabolic alterations, improvements in behavior and ability, and reduced fearfulness [1]. Therapeutic potential Earlier this year, we reported on a clinical trial in which administering HUCMSCs reduced...
May 22, 2024
A paper published in Age and Ageing analyzed the intake of different food groups and whether they accelerate or decelerate biological age in post-menopausal women [1]. Nutrition and biological age Biological age is a better indicator of health and aging than chronological age [2]. Multiple measurements can be used to assess biological age; some of...
February 19, 2024
In Aging, a team of researchers has outlined a possible relationship between low grip strength and compounds in the gut microbiome. The gut-muscle axis As these researchers note, previous work has described many of the various ways in which metabolism is related to age-related muscle dysfunction, including inflammation, oxidative stress, accumulation of advanced glycation end-products...
September 28, 2023
In a recent article in Nature, researchers have restored cardiac regeneration to adult mice by disabling fatty acid oxidation, discovering a potential pathway for human treatments. A question of metabolism As heart muscle cells (myocytes) mature, they make a metabolic switch from glycolysis to the oxidation of fatty acids. Previous research has found that this...
May 17, 2023
Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia BrainThe brain is perhaps the most important organ in the body. While many organs are critical to our survival, the brain contains the self. It is responsible...