Lifespan Research Institute

Tag: Menopause

Menopause
An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality [1]. A controversial therapy One of the first major changes that women undergo as they age is menopause, which usually occurs between 45 and 55 years of age. Menopause not only marks the end of reproduction, the hormonal changes...
Rhesus macaques
In Aging, researchers have published their discovery that three years of caloric restriction in rhesus macaques that are beginning to enter menopause slows their ovarian aging. Closer to people than mice The ovary is one of the first human organs to be seriously affected by aging, with the follicles becoming depleted long before most causes...
Woman with knee osteoarthritis
Recent research has addressed menopause-related molecular processes that impact the high prevalence of knee osteoarthritis in post-menopausal women. Restoration of female sex hormones in a post-menopausal mouse model improved joint health [1]. A centuries-old observation The authors start the article with a quote from the English physician John Haygarth from 1805: the nodosities [irregularities] of...
Elderly woman
In a recent Perspective published in Nature Aging, researchers noted a lack of studies on female-specific physiological factors on aging trajectories. They proposed solutions, including model systems, to address the issue [1]. Most model organisms don't match human sex specificity The use of model organisms, such as worms, fruit flies, and mice, has helped researchers...
Dina Radenkovic
Our interviewee today holds that female reproductive aging, or ovarian aging, is accelerated compared to other organs and that it has a deep impact both on the lives and health of women and on our society as a whole. Nevertheless, ovarian aging continues to be underresearched, with only a handful of companies working in the...