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Tag: Insulin

November 25, 2020
Recent research published in Nature Biomedical Engineering has shown a way to dramatically improve the feasibility of transplanting therapeutic cells, particularly pancreatic islet cells, while protecting them from the recipient’s immune response. PancreasThe pancreas primarily functions as an exocrine and endocrine gland. It supports digestion by excreting digestive enzymes into the small intestines to break...
November 24, 2020
Researchers have discovered a chemical pathway that alleviates many harmful consequences of obesity while having little effect on obesity itself [1]. Obesity is bad for your lifespan. This is one of the fundamental truths of longevity science. Obesity drastically increases our susceptibility to cardiovascular diseases, type 2 diabetes, cancer, and other morbidities. It promotes inflammaging,...
March 04, 2020
A team of researchers led by Dr. Jeffrey Millman at Washington University may be a step closer to a potential solution to diabetes, according to the results of a new study in which replacement beta cells were given to mice. What is diabetes? Diabetes is a disease that occurs when blood glucose levels are constantly...
October 12, 2018
Scientists at Lund University, Sweden showed that it is possible to prevent type 2 diabetes in mice by inhibiting a protein known as VDAC1. This inhibitor might be employed in treating this disease in humans [1]. Abstract Type 2 diabetes (T2D) develops after years of prediabetes during which high glucose (glucotoxicity) impairs insulin secretion. We...
August 09, 2018
Somewhat serendipitously, Salk Institute researchers discovered that depleting the microbiomes of mice causes the animals to have lower levels of blood glucose as well as improved insulin sensitivity [1]. Abstract Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects...