Tag: Insulin

A new open-label, randomized, controlled study published in Cell showed that zero-calorie sweeteners are metabolically active and some might impair glycemic response in healthy adults [1]. What does “sugar-free” mean? The human brain is the main consumer of glucose in the body, and glucose availability is paramount for neurons to generate action potentials and release...

A recent study in Clinical and Translational Medicine followed people who went 5 days without eating and found improvements both immediately afterwards and up to 98 days later. Fasting for longevity Fasting is a practice in which an individual abstains from food and calories for a given length of time. There have been many preclinical...

Recent research published in Nature Biomedical Engineering has shown a way to dramatically improve the feasibility of transplanting therapeutic cells, particularly pancreatic islet cells, while protecting them from the recipient’s immune response. What Is the Pancreas and What Does It Do?The pancreas primarily functions as an exocrine and endocrine gland. It supports digestion by excreting...

Researchers have discovered a chemical pathway that alleviates many harmful consequences of obesity while having little effect on obesity itself [1]. Obesity is bad for your lifespan. This is one of the fundamental truths of longevity science. Obesity drastically increases our susceptibility to cardiovascular diseases, type 2 diabetes, cancer, and other morbidities. It promotes inflammaging,...

A team of researchers led by Dr. Jeffrey Millman at Washington University may be a step closer to a potential solution to diabetes, according to the results of a new study in which replacement beta cells were given to mice. What is diabetes? Diabetes is a disease that occurs when blood glucose levels are constantly...

Somewhat serendipitously, Salk Institute researchers discovered that depleting the microbiomes of mice causes the animals to have lower levels of blood glucose as well as improved insulin sensitivity [1]. Abstract Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects...