January 07, 2021
A gene editing technique published in Nature has proven to be effective in a mouse model of Hutchinson–Gilford progeria syndrome (HGPS). A single error causes tremendous damage HGPS is a well-known disease that causes visible aging and early death in children. In progeria, the lamina that protects the genetic information in the nucleus is greatly...
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently affecting around 390 children. Their average life expectancy is around 13 years, but some affected individuals can live to 20 years. Nuclear lamins are fibrous...
December 04, 2019
If humans ever reach an average lifespan of well over 100 years, what is going to happen? Are we going to be bored with such long lives? "Well," says Prof. Brian Kennedy of the National University of Singapore, "If you ask me: 'Do I want to have cancer at 75? Do I want have Alzheimer’s...