Tag: GrimAge

Researchers have discovered key biomarkers that are strongly linked to all-cause mortality and identified four measurements with independent predictive power. Biological versus chronological This paper opens with a discussion of a familiar fact for people interested in living longer: one's biological age is not the same as one's chronological age [1]. Biological age gives a...

A paper in Cell Genomics has described how age-related systemic inflammation (inflammaging) is related to epigenetic aging as measured by four established clocks. Tying together two well-known aspects of aging Chronic InflammationChronic inflammation refers to a persistent, low-grade buzz of immune activity that settles into the body without the drama of an infection or obvious...

In a study that involved pairs of identical twins, Stanford scientists have shown that a healthy vegan diet leads to a decrease in biological age and possibly to other health benefits [1]. Do you really live longer if you eat well? A good diet can do wonders for health, but it is still unclear if...

Researchers have published the results of a study in Aging Cell, finding some evidence that type 2 diabetes causes accelerated aging. Later-generation clocks only What Are Epigenetic ClocksAn epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different kinds...

Researchers publishing in PNAS have found that well-known epigenetic clocks are valuable in predicting health outcomes, including mortality, in human beings. The usefulness of clocks What Are Epigenetic ClocksAn epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different...

In a paper published in Geroscience, researchers have developed a metric of systemic inflammation and used it to estimate mortality, finding that it performs better than epigenetic clocks. Evaluating a danger This paper begins with familiar discussions about inflammaging and epigenetic clocks, tools that use DNA methylation to estimate biological age. These clocks are also...