July 19, 2023
Researchers have analyzed the activity of genes in the livers, kidneys, and brains of over a hundred mammals and found genes that are consistently associated with longevity [1]. The search for longevity-associated genes Between the shortest-living and the longest-living mammal, there is a more than 100-fold difference in lifespan. This natural difference may be key...
July 13, 2023
Researchers publishing in npj regenerative medicine have found that destroying senescent cells through a well-known senolytic combination gives older killifish back some of their regenerative abilities. Regeneration, for a while Killifish, like starfish and salamanders, are some of the most well-known regenerators of the animal kingdom, able to even regenerate brain tissue [1]. However, these...
July 07, 2023
Scientists have demonstrated that full-body regeneration in cnidarians, a group of animals that includes the jellyfish and hydra, can be driven by signals from senescent cells [1]. This might be the original purpose of cellular senescence. Why can’t we regrow our arms? There are many examples of amazing regenerative abilities in the animal kingdom, but...
June 09, 2023
Scientists have found a possible explanation for bowhead whales’ exceptional lifespan, and it might be translatable to humans [1]. More cells, less cancer With some exceptions, body size is strongly correlated with longevity across species. While this can be explained evolutionarily (larger species have fewer extrinsic threats, which favors slow reproduction and longer lifespan), it...
May 09, 2023
Dr. Vera Gorbunova is a famous geroscientist who, for the last several years, has worked mostly on uncovering the amazing biological mechanisms that are responsible for the enviable longevity and resilience of long-lived species such as the naked mole rat. We talked about those feats of evolution and how they can be harnessed to...
March 24, 2023
Many species have developed amazing mechanisms to cope with various drivers of aging. We have previously interviewed two prominent experts that study those evolutionary marvels: Steven Austad and Emma Teeling. However, this research is not purely academic anymore. A handful of bold entrepreneurs are trying to go commercial, and one of them is Ashley Zehnder,...