February 24, 2025
The Arc Institute, a nonprofit research organization, has published a manuscript on its creation of Evo 2, an AI foundation model that is capable of both understanding and building full genomes of organisms. A new step in understanding biology The authors of this paper, a group of professionals largely from the Arc Institute and well-known...
December 04, 2024
Once confined to the realms of science fiction or relatively crude internet death calculators, AI-driven predictions about longevity are inching closer to reality. Questions about the accuracy and value of these forecasts remain. In recent years, researchers and companies around the globe have been pursuing answers to the ultimate question: How long have we got...
November 08, 2024
Back in 2006, a website called “The Death Clock” appeared on the internet, with a promise to answer one of life’s greatest questions: “When will I die?” Since then, over 60 million people have used the site, which gives a somewhat grim countdown to the day they’ll meet their demise, or does it? Far from...
September 12, 2024
In Aging, researchers from Spain and Luxembourg have described the creation of Single-cell RNA-seq Investigation of Rejuvenation Agents and Longevity (SINGULAR), an atlas for cellular rejuvenation that describes how interventions affect individual cells. Computational biology might light up a better path These researchers begin this paper by describing the problems with current interventions against the...
May 24, 2023
In a recent paper published in International Journal of Medical Sciences, researchers have described how they used artificial intelligence and machine learning tools to find mTOR-inhibiting molecules [1]. mTOR is a common target for lifespan extension interventions The mechanistic target of rapamycin (mTOR) is a well-known molecule in the rejuvenation world. Previous studies have demonstrated...
May 04, 2023
Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm's discoveries to existing compounds. A quest for effective therapeutics What Are Senolytics? Senotherapeutics for Senescent CellsSenolytics work by targeting one of several pro-survival pathways that senescent cells use to evade apoptosis and cling...