A Knowledge Hub for Lifestyle and Supplements
Our lifestyles, diet, activity levels, and environment all play a role in determining how long we will remain healthy (healthspan) and how long we live (lifespan). We are building a knowledge hub to help guide you on best practices and the data supporting various diets, lifestyles, and activities, helping you make informed choices about your health and potential longevity.
Many members of this community are enthusiastic about supplements in the hope that they can influence aging in a positive way and help to slow, delay or even reverse it. However, much of the information about supplements is confusing and contradictory, as well as hype and misleading information designed to sell supplements. That said, some supplements may have some genuine value in the fight against aging, so as part of our educational mission, we review supplements and the studies behind them.
Is Coffee Good or Bad for You?
Coffee contains hundreds of biologically active compounds that influence long-term health. Coffee consumption is associated with lower all-cause and cardiovascular (CV) mortality as well as protection from diabetes, […]
What Is Metformin and Why Do People Take It?
Metformin is widely prescribed for type 2 diabetes; it improves glucose metabolism and thereby reduces diabetic complications. How it works is not well-understood, but we know that metformin mostly interacts with […]
How to Lose Weight Fast and Why You Shouldn’t
Maintaining a healthy weight is a sensible strategy for staying healthy and trying to slow down aging. However, a lot of people try to lose weight fast […]
What is Resveratrol, and is it Good for Longevity?
Resveratrol is a naturally occurring polyphenol commonly found in peanuts, grapes, and some berries. Many benefits have been ascribed to it, including enhanced mitochondrial function, protection from obesity and obesity-related […]
Alpha-Lipoic Acid and Its Effects on Metabolism
Alpha lipoic acid (ALA) was first discovered in 1937, when Esmond Snell found that certain bacteria relied on potato juice to reproduce [1]. This became known as a potato growth factor. Its first […]
Dietary Components That Affect Blood Pressure
While some people must take medication to reduce their blood pressure in order to preserve their healthspan and lifespan, it is usually recommended to try diet- and exercise-based approaches first. […]
What Is Chondroitin Sulfate and What Are Its Effects?
Chondroitin sulfate, widely known as chondroitin, has been shown to reduce mortality by a whopping 39% in a cohort of U.S. adults […]
What Is Low-Dose Naltrexone (LDN)?
Naltrexone is an FDA-approved medication for the treatment of opioid addiction and alcohol dependence [1] that was developed in 1961 [2]. Naltrexone blocks the […]
What Is Glucosamine? A Summary of Glucosamine
This popular supplement has been used for decades for joint pain, but its influence on all-cause mortality is far more interesting in the context of healthy longevity. What is glucosamine? […]
What Is Glutathione? A Summary of Glutathione
Glutathione, known as the master antioxidant within cells, is a tripeptide made of glutamine, cysteine, and glycine [1]. Cysteine, the central amino acid in glutathione, contains a carbon atom […]
What Is Quercetin? A Summary of Quercetin
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this […]
Gut Health and Aging: A Summary of Urolithin A
What are urolithins? Urolithins are not found in food; however, their precursor polyphenols are. Polyphenols are abundantly found in many fruits and vegetables. When eaten, some of the polyphenols are directly […]
Reviewing Cold Therapy for Longevity
The health benefits of the cold therapy have long been touted by mankind, including Hippocrates claiming it cured lethargy and Thomas Jefferson bathing his feet in cold water every morning for decades to maintain good […]
What Is Fasting and How Does it Work?
In this review, we explore the practice of fasting and how it differs to caloric restriction. What Is Fasting? […]
- Nicotinamide Adenine Dinucleotide (NAD)
- Niacin (NA)
- Nicotinamide mononucleotide (NMN)
- Nicotinamide riboside (NR)
