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Stealth BioTherapeutics

Organization Description

Stealth BioTherapeutics is a biopharmaceutical company developing therapies to treat mitochondrial dysfunction, mitochondrial diseases, and common diseases of aging.

Their lead investigational product candidate, elamipretide, is a peptide compound that readily penetrates cell membranes, and targets the inner mitochondrial membrane where it binds reversibly to cardiolipin. They claim that elamipretide increases mitochondrial respiration, improves electron transport chain function and ATP production and reduces formation of pathogenic ROS levels.