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Tag: Wnt

November 11, 2020
Using a novel 3D lung organoid model, new research published in Cell Stem Cell has shed light on the body's infection response to COVID-19. LungsOur lungs transfer ambient oxygen into the bloodstream while transferring out carbon dioxide. The airflow generated by our lungs also allows for speech as it passes through our vocal cords. Lung...
February 07, 2020
Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn't a particularly good birthday present. (Wow, what'd I get this year? Just what I didn't want: sarcopenia and hearing loss!) Given...
July 16, 2019
Researchers at the University of Helsinki have shown why the regenerative capacity of the cells lining the intestines declines with age and that targeting a particular enzyme can restore the regenerative potential of this tissue. Notum blocks the Wnt pathway During normal function, the cells of the intestinal epithelium, a single cell layer that forms...
May 07, 2019
San Diego-based biotechnology company Samumed has recently announced that it will be moving to phase 3 clinical trials of its drug lorecivivint (SM04690) for the treatment of knee osteoarthritis. What is osteoarthritis? Osteoarthritis is the most common form of arthritis in the knee and a leading cause of adult disability, particularly among older people. This...
March 04, 2019
Researchers from the University of Luxembourg and the German Cancer Research Center have rejuvenated stem cells in the brains of old mice. The rejuvenated stem cells appear to improve regeneration in areas of damaged or diseased brain tissue. A new way to model stem cells A new study that was published in the journal Cell...
August 08, 2018
Today, we were pleased to hear that Samumed, a San Diego-based biotech company working on regenerative medicine, has just raised $438 million towards developing anti-aging therapies. SAN DIEGO – August 6, 2018 – Samumed, LLC, announced today that it has closed its A-6 Round of equity issuance with $438 million, bringing its total equity raised...