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Tag: Wnt

Disc degeneration
In Aging Cell, researchers have published detailed information on why the antioxidant pyrroloquinoline quinone (PQQ), which is known to be safe in humans, alleviates age-related disc degeneration in mice. A return to antioxidants Oxidative stress was once considered to be the core of aging, a concept that has since been supplanted by more detailed and...
Gray hair
Researchers publishing in Nature have made the surprising discovery that pigmentation cells (melanocytes) can naturally transition back into the stem cell state in a process called dedifferentiation. A kinship with hair follicle cells These researchers begin their study by discussing stem cells and their proliferation. In the common understanding, which appears to be true for...
Swimming mouse
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer's and outlined the genes involved. Niacin: Benefits, Side Effects, and ResearchNiacin is a form of vitamin B3. It was discovered in 1937 by Conrad Elvehjem and originally used to treat pellagra, a disease...
Lungs
Using a novel 3D lung organoid model, new research published in Cell Stem Cell has shed light on the body's infection response to COVID-19. Generating lung tissue in vitro  Lung tissue regeneration is an elusive scientific goal that would have a major implications for treating patients in need of lung transplantation. Relative to other organs,...
Optimism
Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn't a particularly good birthday present. (Wow, what'd I get this year? Just what I didn't want: sarcopenia and hearing loss!) Given...
San Diego-based biotechnology company Samumed has recently announced that it will be moving to phase 3 clinical trials of its drug lorecivivint (SM04690) for the treatment of knee osteoarthritis. What is osteoarthritis? Osteoarthritis is the most common form of arthritis in the knee and a leading cause of adult disability, particularly among older people. This...